| 1. |
- Andersson, Eva, et al.
(författare)
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Improved Physical Capacity in a Project with Guided Physical Activity for Persons with Depression or Anxiety.
- 2010
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Konferensbidrag (refereegranskat)abstract
- Background: Higher physical capacity is correlated with increased health. Knowledge in this area regarding psychiatric diseases is sparse. Purpose: The aim was to study aerobic and several strength capacities in a physical activity project for persons with depression or anxiety. Methods: Eighty-four persons (56 women and 28 men) with depression or anxiety were recruited from psychiatric out-patient clinics in Stockholm. Their mean age and BMI was 46 (21-80) years and 26 (17-41) kg/m2, respectively. 50% were sick-listed. 50% had BMI>25. Aerobic and strength tests were chosen by each subgroup´s project leaders. Directed physical activity was given, in groups 10-15, 1 hour twice/week during 8-12 weeks. Results: Significant changes (p<0.05, of all n=84) between pre- and post tests were seen in submaximal cycle test (11% enhanced values, n=56) and distance of 6 minutes walk test (16%, n=15) as well as in strength tests for the back for the back (i.e. time in static horizontal belly-back, 40%, n=44), abdominal and hip flexors (i.e. number of hip flexion sit-ups, 45%, n=38), leg (i.e. standing with 90O in hips and knees, 48%, n=56) and arm with shoulder muscles (i.e. number of raising weights alternately with the arms, 46%, n=32). Hand grip tests, BMI or blood pressure values did not change significantly. Conclusions: Directed 8-12 weeks physical activity programs can improve physical fitness in individuals with depression or anxiety.
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| 2. |
- Andersson, Henrik, et al.
(författare)
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Benefit measures for noise abatement : calculations for road and rail traffic noise
- 2013
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Ingår i: European Transport Research Review. - : Springer Science and Business Media LLC. - 1867-0717 .- 1866-8887. ; 5:3, s. 135-148
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Tidskriftsartikel (refereegranskat)abstract
- PurposeThe aim of this study is to estimate monetary abatement values for road and rail traffic noise that can be used for policy purposes. However, a main objective is to critically discuss the assumptions necessary to convert the monetary values elicited in willingness to pay (WTP) studies to values than can be use for policy purposes.MethodsWe employ the hedonic regression technique on Swedish data to elicit individuals' preferences for noise abatement. Our elicited values are then converted to policy values and critically examined based on findings from a literature review.ResultsWe show that WTP for road and rail not only differs in levels but also that the relationship between the noise level and the marginal value differs between the two sources. We also show that a health cost component added to the WTP estimate, based on the assumption of uninformed property buyers, will be small but not negligible and that also modest differences in the assumption of the discount rates will have a significant effect on the estimated values.ConclusionsThe main implications from this study are: (i) WTP for road and railway noise abatement differs not only on absolute but also marginal levels, (ii) Even small differences in the chosen discount rate, which is necessary to convert WTP values from a hedonic price study to policy values, have large effects on the policy values, and (iii) We show how to add a health cost component to the WTP estimates in order for the monetary estimates to reflect the total social cost. However, we argue that the motivation for doing so is weak and that more research is needed on this issue.
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| 3. |
- Andersson, Henrik, et al.
(författare)
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Property Prices and Exposure to Multiple Noise Sources : Hedonic Regression with Road and Railway Noise
- 2010
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Ingår i: Environmental and Resource Economics. - : Springer Science and Business Media LLC. - 0924-6460 .- 1573-1502. ; 45:1, s. 73-89
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Tidskriftsartikel (refereegranskat)abstract
- This study examines the effect of road and railway noise on property prices. It uses the hedonic regression technique on a Swedish data set that contains information about both road and railway noise for each property, and finds that road noise has a larger negative impact on the property prices than railway noise. This is in line with the evidence from the acoustical literature which has shown that individuals are more disturbed by road than railway noise, but contradicts recent results from a hedonic study on data of the United Kingdom.
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| 4. |
- Eklund, Lina, et al.
(författare)
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Time to play : the rationalization of leisure time
- 2012
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Ingår i: Proceedings of the 2012 iConference. - New York : Association for Computing Machinery (ACM). - 9781450307826 ; , s. 145-151
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Konferensbidrag (refereegranskat)abstract
- This study explores how rationalization logic and rationalization processes influence digital gaming by looking at how players value and manage the time they spend on games. The study is framed in a discussion of leisure time, critical theories of computation and rationalization theory. Qualitative interview data is used in an inductive and phenomenology inspired approach. The results show two frames of understanding of gaming. First, games are perceived as media products and playing as a waste of time. Secondly, digital gaming is a hobby, a social activity highly valued within the framework of a rational time economy. We conclude that even though we are seeing a rationalization of leisure time in gaming, that rationalization process must be understood in the context of individualization within the new network society. This means that players are involved in a 'rational individualization' process where their management of leisure time and gaming activities are part of an ongoing identity project.
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| 5. |
- Eliasson, Jonas, et al.
(författare)
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The unexpected “yes!” : Explanatory factors behind the positive attitudes to congestion charges in Stockholm
- 2011
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Ingår i: Transport Policy. - : Elsevier BV. - 0967-070X .- 1879-310X. ; 18:4, s. 636-647
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Tidskriftsartikel (refereegranskat)abstract
- Several authors have argued that acceptability for road pricing is likely to increase with familiarity. The experiences in Stockholm, where a trial period with congestion charges changed the public opinion from negative to positive, support this hypothesis. Analysing acceptability and attitudes in Stockholm allows us to study a situation where the population is in fact familiar with congestion charges, and explore what the decisive factors for acceptability are in such a situation. By analysing a survey collected after the referendum and the subsequent reintroduction of the charges, we analyse the prerequisites to achieve acceptability given that the public is familiar with congestion charges.As expected, low car dependence and good transit supply are associated with high acceptability. But the two most important factors turn out to be beliefs about the charges' effectiveness, and general environmental attitudes. The importance of beliefs and perceptions of the effects of the charges underscores the importance of both careful system design and careful evaluation and results communication. The strong connection between environmental concerns and positive attitudes to congestion charges underscores the importance of considering and "marketing" the charges' environmental effects. In Stockholm, the politicians' decision to "re-label" the congestion charges to "environmental charges" and emphasising their positive effects on air quality may very well have had a positive impact on acceptability.
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| 6. |
- Escott-Price, Valentina, et al.
(författare)
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Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease
- 2014
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 9:6, s. e94661-
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Tidskriftsartikel (refereegranskat)abstract
- Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an alternative gene-wide analytical approach which tests for patterns of association within genes, in the powerful genome-wide association dataset of the International Genomics of Alzheimer's Project Consortium, comprising over 7 m genotypes from 25,580 Alzheimer's cases and 48,466 controls. Principal Findings: In addition to earlier reported genes, we detected genome-wide significant loci on chromosomes 8 (TP53INP1, p = 1.4x10(-6)) and 14 (IGHV1-67 p = 7.9x10(-8)) which indexed novel susceptibility loci. Significance: The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimer's disease.
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| 7. |
- Ferencz, Beata, et al.
(författare)
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The Benefits of Staying Active in Old Age : Physical Activity Counteracts the Negative Influence of PICALM, BIN1, and CLU Risk Alleles on Episodic Memory Functioning
- 2014
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Ingår i: Psychology and Aging. - : American Psychological Association (APA). - 0882-7974 .- 1939-1498. ; 29:2, s. 440-449
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Tidskriftsartikel (refereegranskat)abstract
- PICALM, BIN1, CLU, and APOE are top candidate genes for Alzheimer's disease, and they influence episodic memory performance in old age. Physical activity, however, has been shown to protect against age-related decline and counteract genetic influences on cognition. The aims of this study were to assess whether (a) a genetic risk constellation of PICALM, BIN1, and CLU polymorphisms influences cognitive performance in old age; and (b) if physical activity moderates this effect. Data from the SNAC-K population-based study were used, including 2,480 individuals (age range = 60 to 100 years) free of dementia at baseline and at 3- to 6-year follow-ups. Tasks assessing episodic memory, perceptual speed, knowledge, and verbal fluency were administered. Physical activity was measured using self-reports. Individuals who had engaged in frequent health-or fitness-enhancing activities within the past year were compared with those who were inactive. Genetic risk scores were computed based on an integration of risk alleles for PICALM (rs3851179 G allele, rs541458 T allele), BIN1 (rs744373 G allele), and CLU (rs11136000 T allele). High genetic risk was associated with reduced episodic memory performance, controlling for age, education, vascular risk factors, chronic diseases, activities of daily living, and APOE gene status. Critically, physical activity attenuated the effects of genetic risk on episodic memory. Our findings suggest that participants with high genetic risk who maintain a physically active lifestyle show selective benefits in episodic memory performance.
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| 8. |
- Haraldsson, Mattias, et al.
(författare)
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Marginalkostnadsskattningar för buss och lätt lastbil : buller, trafiksäkerhet och vägslitage
- 2012
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Syftet med denna rapport är att beräkna marginalkostnader för buller, trafiksäkerhet och vägslitage för bussar och lätta lastbilar. Bullerkostnaderna beräknas med modellen Nord 2000 tillsammans med kalkylvärden från ASEK 5. Marginalkostnaden för trafiksäkerhet beräknas utifrån olycksstatistik i STRADA, en fördelning av trafikarbete mellan landsbygd och tätort samt kalkylvärden från ASEK 5. Marginalkostnaden för vägslitage beräknas genom att justera de värden för genomsnittliga tunga fordon som finns i ASEK 5. Justeringen görs utifrån antalet standardaxlar. För bussar beräknas antalet standardaxlar med hjälp av statistik från fordonsregistret, medan antalet standardaxlar hos lätta lastbilar beräknas utifrån fordonstypens maximala totalvikt. Marginalkostnaden för buller har differentierats på vägar med olika ÅDT och omgivning med olika tät befolkning.
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| 9. |
- Haraldsson, Mattias, et al.
(författare)
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Samhällsekonomisk analys av rundvirkestransporter med 90-tonslastbilar : delprojekt inom Sammodalitetsprojektet
- 2012
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Syftet med denna rapport är att göra en samhällsekonomisk analys som visar hur de kostnader som rundvirkestransporter med lastbil ger upphov till, skulle påverkas om fordonens totalvikt tilläts öka från 60 till 90 ton och samtidigt få en tillåten maxlängd på 30 meter. Analysen görs på två sätt. Först redovisas genomsnittliga kostnader per fordonskilometer för olika fordonsstorlekar. Dessutom görs en kalkyl, som utgår från scenarier om hur mycket trafikarbetet skulle påverkas om större fordon tilläts. För att analysera hur transporterna av rundvirke genomförs i olika scenarier används den svenska godstransportmodellen Samgods. Flödesberäkningar från denna används därefter tillsammans med uppgifter från Nationella vägdatabasen (NVDB) för att beräkna samhällsekonomiska kostnader. Dessa beräkningar tar hänsyn till vägtyp och andra lokala förutsättningar och fångar därmed upp den variation i samhällsekonomiska kostnader som finns. Beräkningarna sammanfattas med den totala kostnaden för att transportera rundvirke med lastbil i Sverige under ett år. Enligt simuleringarna minskar trafikarbetet med 21 procent om 60-tonsfordon ersätts med 90-tonsfordon, om man inte tar hänsyn till brorestriktionerna. Detta ger en total samhällsekonomisk kostnadssänkning med 4 procent eller 163 miljoner kronor årligen. Då ska man dock komma ihåg att kostnaden för bärighetsåtgärder på broar, vilket är en förutsättning för att scenariot ska kunna realiseras, inte är inkluderade i analysen. Om vissa broar är spärrade för trafik med 90-tonsfordon är det inte generellt lönsamt att ersätta 60-tonsfordon, eftersom den samhällsekonomiska kostnaden då ökar med 15 procent. Redan idag är det dock möjligt att använda 90-tonsfordon på ett antal stråk som är viktiga för rundvirkestransporter.
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| 10. |
- Jern, Patrick, et al.
(författare)
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Are single nucleotide polymorphisms in the oxytocin and vasopressin 1A/1B receptor genes likely candidates for variation in ejaculatory function?
- 2012
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Ingår i: Bju International. - 1464-4096. ; 110:11C
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES To investigate associations between single nucleotide polymorphisms (SNPs) linked to the oxytocin, To investigate these associations in a large, population-based sample. PATIENTS AND METHODS In all, 1517 male twins and non-twin brothers of twins aged 18-45 years (mean = 26.43; SD = 4.87) A Bayesian linear mixed-effects model, which appropriately controls for between subjects dependence, We corrected for multiple testing using a linkage disequilibrium correlation measure. RESULTS We found a heterozygote effect on one SNP in the oxytocin receptor gene (rs75775), so that individuals Several SNPs in the arginine vasopressin receptor genes had rare or very rare genotypes. This study CONCLUSIONS Our results regarding the oxytocin receptor polymorphisms support previous studies that indicate a Oxytocin receptor genes are, for example, unlikely suitable targets for pharmacogenetic intervention Rare variants in arginine vasopressin receptor genes may have significant effects on premature
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