| 1. |
- Aizpurua, Javier, et al.
(författare)
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Light scattering in gold nanorings
- 2004
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Ingår i: Journal of Quantitative Spectroscopy & Radiative Transfer. ; 89, s. 11-16
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Tidskriftsartikel (refereegranskat)
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| 2. |
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| 3. |
- Eliasson, Charlotte, 1973, et al.
(författare)
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Multivariate evaluation of doxorubicin surface-enhanced Raman spectra.
- 2001
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Ingår i: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. - 1386-1425. ; 57:9, s. 1907-15
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Tidskriftsartikel (refereegranskat)abstract
- Multivariate evaluation of surface-enhanced Raman spectra of doxorubicin in plasma was performed. In a principal component analysis (PCA) all spectral features were modelled into three principal components. The major variation of the data was shown to be the variation of doxorubicin Raman signal together with the doxorubicin fluorescence, whereas the variation due to plasma was of minor importance. It was also shown that the surface-enhanced Raman scattering (SERS) measurements were independent on such factors as measurement occasion and silver colloids. The presented results show that with some improvements, quantification of doxorubicin directly in plasma could be possible.
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| 4. |
- Lorén, Anders, 1974, et al.
(författare)
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Feasibility of quantitative determination of doxorubicin with surface-enhanced Raman spectroscopy
- 2001
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Ingår i: Journal of Raman Spectroscopy. - : Wiley. - 0377-0486 .- 1097-4555. ; 32:11, s. 971-974
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Tidskriftsartikel (refereegranskat)abstract
- Surface-enhanced Raman spectroscopy (SERS) was performed using excitation at 488 nm in a blood plasma-doxorubicin-silver colloid system. With a blood plasma content of 1%, a partial least-squares calibration of the doxorubicin was made in the 10-750 nM range. Predictions for a test set generated a root mean square error of prediction of 70 nM. The use of SERS and chemometrics in complex systems made it possible to use the highly informative Raman signals even at low concentrations without the need for sample pretreatment such as extraction. Copyright © 2001 John Wiley & Sons, Ltd.
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| 6. |
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| 7. |
- Prikulis, Juris, 1973, et al.
(författare)
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Optical spectroscopy of single trapped metal nanoparticles in solution
- 2004
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Ingår i: Nano letters (Print). - : American Chemical Society (ACS). - 1530-6984 .- 1530-6992. ; 4:1, s. 115-118
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Tidskriftsartikel (refereegranskat)abstract
- We present a simple method for the optical manipulation and spectroscopy of colloidal silver nanoparticles in aqueous solution using optical tweezers combined with dark-field microscopy. Because of their localized plasmon resonances, single trapped metal nanoparticles can be used as efficient near-field optical probes, with potential applicability in surface-enhanced spectroscopy, near-field microscopy, and biochemical sensing schemes. As a proof of principle, we study the near-field optical interaction between a trapped and an immobilized Ag nanoparticle.
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| 8. |
- Ramser, Kerstin, et al.
(författare)
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Resonance Raman spectroscopy of optically trapped functional erythrocytes
- 2004
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Ingår i: Journal of Biomedical Optics. - : SPIE-Intl Soc Optical Eng. - 1083-3668 .- 1560-2281. ; 9:3, s. 593-600
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Tidskriftsartikel (refereegranskat)abstract
- We introduce a novel setup combining a micro-Raman spectrometer with external optical tweezers, suitable for resonance Raman studies of single functional trapped cells. The system differs from earlier setups in that two separate laser beams used for trapping and Raman excitation are combined in a double-microscope configuration. This has the advantage that the wavelength and power of the trapping and probe beam can be adjusted individually to optimize the functionality of the setup and to enable the recording of resonance Raman profiles from a single trapped cell. Trapping is achieved by tightly focusing infrared (IR) diode laser radiation (830 nm) through an inverted oil-immersion objective, and resonance Raman scattering is excited by the lines of an argon:krypton ion laser. The functionality of the system is demonstrated by measurements of trapped single functional erythrocytes using different excitation lines (488.0, 514.5, and 568.2 nm) in resonance with the heme moiety and by studying spectral evolution during illumination. We found that great care has to be taken in order to avoid photodamage caused by the visible Raman excitation, whereas the IR trapping irradiation does not seem to harm the cells or alter the hemoglobin Raman spectra. Stronger photodamage is induced by Raman excitation using 488.0- and 514.5-nm irradiation, compared with excitation with the 568.2-nm line.
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