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| 2. |
- Breimer, Michael, 1951, et al.
(author)
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Selected ion monitoring of glycospingolipid mixtures. Identification of several blood group type glycolipids in the small intestine of an individual rabbit.
- 1979
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In: Biomedical mass spectrometry. - : Wiley. - 0306-042X .- 1096-9888. ; 6:6, s. 231-41
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Journal article (peer-reviewed)abstract
- A novel application of selected ion monitoring was used for a mixture of non-acid glycosphingolipids of one rabbit small intestine. Earlier studies of permethylated and permethylated-reduced (LiAIH4) derivatives of model compounds have revealed a specificity and abundance of saccharide ions (terminal monosaccharide(s), disaccharide, trisaccharide, etc., and all sugars plus fatty acid) and of ceramide fragments that permit a conclusive detection of separate glycolipid species in a mixture. The sample (50-200 micrograms) was evaporated slowly (1-5 degrees C min-1 from 150-350 degrees C) from the direct inlet probe of an MS 902 mass spectrometer (electron ionization). Mass spectra with fragments up to about m/z 200 were collected on-line by a computer system. A successive partial separation was obtained for glycolipids with from one up to seven sugars. The structures of eight different compounds were identified. They all had 16:0, 22:0 and 24:0 2-hydroxy fatty acids and 18:0 trihydroxy base (phytosphingosine) as major ceramide components. The dominating complex glycolipid was a hexaglycosylceramide with a blood group B type of sequence. A blood group A type sequence was found in a second hexaglycosylceramide. In support of this, the native mixture showed blood group A and B activity. An intense peak, m/z 182, collected from methylated derivatives were evidence for a dominating type 2 carbohydrate chain of the core tetrasaccharide.
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| 6. |
- Karlsson, H.G., et al.
(author)
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An electronic delay circuit for biomedical simulations.
- 1971
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In: Medical & Biological Engineering & Computing. - 0140-0118. ; 9:6, s. 721-724
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Journal article (peer-reviewed)abstract
- In many control problems, e.g. in biology, time delays of the order of seconds or more play an important role. The present device is intended for simulations of such problems. Its accuracy (0·1 per cent) is of the same magnitude as that for most analogue computer components. It has been used in preliminary experiments (Fig. 5) to study biological rhythms. However, many differential equations with time delay, including those with more complicated weighting functions than that in Fig. 5, can be successfully studied using this method.
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| 7. |
- Komi, P V, et al.
(author)
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Skeletal muscle fibres and muscle enzyme activities in monozygous and dizygous twins of both sexes.
- 1977
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In: Acta Physiologica Scandinavica. - 0001-6772 .- 1365-201X. ; 100:4, s. 385-92
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Journal article (peer-reviewed)abstract
- Significance of the genetic component in determining the interindividual variation observed in skeletal muscle fibre composition and enzyme activities was investigated in 31 pairs of male and female monozygous (MZ) and dizygous (DZ) twins, whose ages ranged in all but one pair (11 years) from 15 to 24 years. Percent distribution of slow twitch muscle fibres and activities of Ca2+ and Ng2+ stimulated ATPases, creatine phosphokinase, myokinase, phosphorylase, lactate dehydrogenase (LDH) and distribution of its isozyme LDH-1 were all analyzed in biopsy samples taken from the vastus lateralis muscle. The data disclosed that in contrast to DZ twins the MZ twins of both sexes had an essentially identical muscle fibre composition. Calculation of the heritability estimate for this parameter gave the values of 99.5% and 92.8%, respectively for males and females. In contrast to the fibre composition presence of a significant genetic component was not observed in any of the enzyme activities studied. It was concluded that there is a predominant genetic influence on the skeletal muscle fibre composition in man, and thus also on the potential capacity of the muscles to perform work.
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| 8. |
- Thorstensson, Alf, et al.
(author)
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Effect of strength training on EMG of human skeletal muscle.
- 1976
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In: Acta Physiologica Scandinavica. - 0001-6772 .- 1365-201X. ; 98:2, s. 232-6
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Journal article (peer-reviewed)abstract
- The effects of an 8 weeks period of systematic progressive strength training on the EMG activity of the leg extensor muscles (vastus lateralis and rectus femoris) were investigated in 8 healthy male subjects (22-31 yrs). After training there were indications (n.s.) of a decline in integrated EMG (IEMG) during maximal isometric knee extension as well as in the IEMG vs isometric force relationship. The averaged motor unit potential (AMUP) did not demonstrate any significant changes due to the strength training regimen. In conformity with earlier findings no or only minor alterations were observed in anthropometrics, muscle enzyme activities and fibre composition. The fibre area ratio indicated a specific effect of the training stimuli on the fast twitch muscle fibres. Thus, EMG-analyses, as employed in the present study, did not provide any conclusive additional explanation as to the mechanisms behind the well established gains in muscle strength performance induced by the applied strength training program.
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| 9. |
- Watanabe, A, et al.
(author)
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Gunnar Fant 60 years
- 1979
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In: TMH-QPSR. ; 20:2, s. 1-45
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Journal article (peer-reviewed)
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