| 1. |
- Aad, G., et al.
(författare)
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- 2012
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Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; :12
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Katsiotis, Christos S., et al.
(författare)
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Processability of mesoporous materials in fused deposition modeling for drug delivery of a model thermolabile drug
- 2023
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Ingår i: International Journal of Pharmaceutics. - : Elsevier. - 2590-1567. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- The incorporation of drug-loaded mesoporous materials in dosage forms prepared with fused deposition modeling (FDM) has shown the potential to solve challenges relating to additive manufacturing techniques, such as the stability of poorly-soluble drugs in the amorphous state. However, the addition of these non-melting mesoporous materials significantly affects the mechanical properties of the filament used in FDM, which in turn affects the printability of the feedstock material. Therefore, in this study a full-factorial experimental design was utilized to investigate different processing parameters of the hot melt extrusion process, their effect on various mechanical properties and the potential correlation with the filaments' printability. The thermolabile, poorly-soluble drug ibuprofen was utilized as a model drug to assess the potential of two mesoporous materials, Mesoporous Magnesium Carbonate (MMC) and a silica-based material (MCM-41), to thermally protect the loaded drug. Factorial and principal components analysis displayed a correlation between non-printable MCM-41 filaments and their mechanical properties where printable filaments had a maximum stress >7.5 MPa and a Young's modulus >83 MPa. For MMC samples there was no clear correlation, which was in large part attributed to the filaments' inconsistencies and imperfections. Finally, both mesoporous materials displayed a thermal protective feature, as the decomposition due to the thermal degradation of a significant portion of the thermolabile drug was shifted to higher temperatures post-loading. This highlights the potential capability of such a system to be implemented for thermosensitive drugs in FDM applications.
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| 3. |
- Abbott, Benjamin W., et al.
(författare)
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Biomass offsets little or none of permafrost carbon release from soils, streams, and wildfire : an expert assessment
- 2016
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Ingår i: Environmental Research Letters. - : IOP Publishing. - 1748-9326. ; 11:3
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Tidskriftsartikel (refereegranskat)abstract
- As the permafrost region warms, its large organic carbon pool will be increasingly vulnerable to decomposition, combustion, and hydrologic export. Models predict that some portion of this release will be offset by increased production of Arctic and boreal biomass; however, the lack of robust estimates of net carbon balance increases the risk of further overshooting international emissions targets. Precise empirical or model-based assessments of the critical factors driving carbon balance are unlikely in the near future, so to address this gap, we present estimates from 98 permafrost-region experts of the response of biomass, wildfire, and hydrologic carbon flux to climate change. Results suggest that contrary to model projections, total permafrost-region biomass could decrease due to water stress and disturbance, factors that are not adequately incorporated in current models. Assessments indicate that end-of-the-century organic carbon release from Arctic rivers and collapsing coastlines could increase by 75% while carbon loss via burning could increase four-fold. Experts identified water balance, shifts in vegetation community, and permafrost degradation as the key sources of uncertainty in predicting future system response. In combination with previous findings, results suggest the permafrost region will become a carbon source to the atmosphere by 2100 regardless of warming scenario but that 65%-85% of permafrost carbon release can still be avoided if human emissions are actively reduced.
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| 6. |
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| 7. |
- Frenning, Göran, et al.
(författare)
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Dielectric and Li transport properties of electron conducting and non-conducting sputtered amorphous Ta2O5 films
- 2001
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Ingår i: Electrochimica Acta. - 0013-4686 .- 1873-3859. ; 46:13-14, s. 2041-2046
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Tidskriftsartikel (refereegranskat)abstract
- Two types of sputtered thin film amorphous tantalum oxide (Ta2O5) were studied: one electron conducting Ta2O5 (ec-Ta2O5) and the other non-conducting Ta2O5 (nc-Ta2O5). The as-deposited films were characterized by impedance spectroscopy (IS) and isothermal transient ionic current (ITIC) measurements. From IS, the dc conductivity 2×10−14 S/cm was obtained for the ec-Ta2O5 film at an applied ac potential of 50 mV whereas a value ≤1×10−17 S/cm was obtained for the nc-Ta2O5 film. Li conducting properties were studied using the galvanostatic intermittent titration technique and ITIC measurements on the intercalated samples. Despite the very dissimilar dc conductivities of the as-deposited films, the two Ta2O5 samples showed surprisingly similar Li ion conducting properties for small Li/Ta2O5 ratios. The Li ion mobility was in the range 1.1×10−9–3.0×10−9 cm2/V s for both films. However, the Li storage behaviour as well as the chemical diffusion coefficient differed. For the nc-Ta2O5 film a plateau was observed in the equilibrium potential vs. composition curve for Li/Ta2O5 ratios between 7×10−5 and 2×10−3. This plateau was likely to have been caused by attractive interactions between the intercalated ions, possibly large enough to cause phase separation. The attractive interactions were shown to suppress the chemical diffusion coefficient in this composition range.
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| 8. |
- HENRIKSSON, JAN
(författare)
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Biologiskt värdefulla träd i Fide/Öja och Bäl/Vallstena 2007-2009
- 2009
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Denna rapport presenterar resultatet från en omfattande inventering av träd på Gotland 2007 till 2009. Den är en del av Länsstyrelsen i Gotlands läns arbete med det nationella åtgärdsprogrammet för Särskilt skyddsvärda träd i kulturlandskapet. Två värdetrakter för ädellövskog, Bäl/Vallstena och Fide/Öja, har kartlagts. Sammanlagt har 18 817 träd klassats som biologiskt värdefulla, 10 360 i Bäl/Vallstena och 8 457 i Fide/Öja.
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