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| 2. |
- Görtz, Stefan, et al.
(författare)
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Standard Unstructured Grid Solutions for Cranked Arrow Wing Aerodynamics Project International F-16XL
- 2009
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Ingår i: Journal of Aircraft. - : American Institute of Aeronautics and Astronautics (AIAA). - 0021-8669 .- 1533-3868. ; 46:2, s. 385-408
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Tidskriftsartikel (refereegranskat)abstract
- Steady and unsteady viscous flow simulations of a full-scale, semispan, and full-span model of the F-16XL-1 aircraft are performed with three different computational fluid dynamics codes using a common unstructured grid. Six different flight conditions are considered. They represent Reynolds and Mach number combinations at subsonic speeds, with and without sideslip. The steady computations of the flow at these flight conditions are made with several Reynolds-averaged Navier-Stokes turbulence models of different complexity. Detached-eddy simulation, delayed detached-eddy simulation, and an algebraic hybrid Reynolds-averaged Navier-Stokes/large-eddy simulation model are used to quantify unsteady effects at the same flight conditions. The computed results are compared with flight-test data in the form of surface pressures, skin friction, and boundary-layer velocity profiles. The focus of the comparison is on turbulence modeling effects and effects of unsteadiness. The overall agreement with flight data is good, with no clear trend as to which physical modeling approach is superior for this class of flow. The Reynolds-averaged Navier-Stokes turbulence models perform well in predicting the flow in an average sense. However, some of the flow conditions involve locally unsteady flow over the aircraft, which are held responsible for the scatter between the different turbulence modeling approaches. The detached-eddy simulations are able to quantify the unsteady effects, although they are not consistently better than the Reynolds-averaged Navier-Stokes turbulence models in predicting the flow in an average sense in these flow regions. Detached-eddy simulation fails to predict boundary-layer profiles consistently over a range of flow regimes, with delayed detached-eddy simulation and hybrid Reynolds-averaged Navier-Stokes/large-eddy simulation models offering a remedy to recover some of the predictive capabilities of the underlying Reynolds-averaged Navier-Stokes turbulence model. Nonetheless, the confidence in the predictive capabilities of the computational fluid dynamics codes with regard to complex vortical flowfields around high-performance aircraft of this planform increased significantly during this study.
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| 3. |
- Birney, Ewan, et al.
(författare)
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Prepublication data sharing
- 2009
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 461:7261, s. 168-170
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Tidskriftsartikel (refereegranskat)abstract
- Rapid release of prepublication data has served the field of genomics well. Attendees at a workshop in Toronto recommend extending the practice to other biological data sets.
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| 4. |
- Koyi, Hemin A., et al.
(författare)
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The mechanical relationship between strike-slip faults and salt diapirs in the Zagros fold-thrust belt
- 2008
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Ingår i: Journal of the Geological Society. - 0016-7649 .- 2041-479X. ; 165, s. 1031-1044
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Tidskriftsartikel (refereegranskat)abstract
- Analogue models are used to study the mechanical relationship between basement strike-slip faults and salt diapirs. Displacement along a strike-slip fault in 1 g models resulted in extension along pre-existing jogs and the formation of oblique extensional faults, where reactive diapirs were triggered in some models. In the centrifuge models prescribed cuts, simulating pre-existing structures, were reactivated during simple shear deformation of the models, resulting in formation of pull-apart basins, which were intruded by diapirs. The models show that because of the low ratio of salt to overburden thickness in the Zagros (0.15-0.35). It is unlikely that diapirs have formed solely, if at all as a result of movement along basement strike-slip faults. Two mechanisms are suggested. First, pre-kinematic thin overburden and continuous movement along a releasing bend in the cover units may have triggered some of the diapirs in the Zagros, which were later downbuilt to their current geometry by additional sedimentation. Second, movement along the strike-slip faults (e.g. the Kazerun and Mangarak faults) induced oblique movement along NW-SE Zagros structures (folds or thrusts) resulting in the formation of pull-part basins where diapirs were eventually intruded. Fault plane solution of shallow earthquakes supports the second scenario, which is also in agreement with previous interpretations that some of the salt diapirs associated with basement faults are younger than Zagros shortening and young southwestwards.
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| 5. |
- Poole, Kate, et al.
(författare)
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Molecular-scale topographic cues induce the orientation and directional movement of fibroblasts on two-dimensional collagen surfaces
- 2005
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Ingår i: Journal of Molecular Biology. - : Elsevier BV. - 0022-2836 .- 1089-8638. ; 349:2, s. 380-386
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Tidskriftsartikel (refereegranskat)abstract
- Collagen fibres within the extracellular matrix lend tensile strength to tissues and form a functional scaffold for cells. Cells can move directionally along the axis of fibrous structures, in a process important in wound healing and cell migration. The precise nature of the structural cues within the collagen fibrils that can direct cell movement are not known. We have investigated the structural features of collagen that are required for directional motility of mouse dermal fibroblasts, by analysing cell movement on two-dimensional collagen surfaces. The surfaces were prepared with aligned fibrils of collagen type I, oriented in a predefined direction. These collagen-coated surfaces were generated with or without the characteristic 67 nm D-periodic banding. Quantitative analysis of cell morphodynamics showed a strong correlation of cell elongation and motional directionality with the orientation of D-periodic collagen microfibrils. Neither directed motility, nor cell body alignment, was observed on aligned collagen lacking D-periodicity, or on D-periodic collagen in the presence of peptide containing an RGD motif. The directional motility of fibroblast cells on aligned collagen type I fibrils cannot be attributed to contact guidance, but requires additional structural information. This allows us to postulate a physiological function for the 67 nm periodicity.
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