| 1. |
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| 2. |
- Alfs, D., et al.
(författare)
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Drift chamber calibration and particle identification in the P-349 experiment
- 2019
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Ingår i: MESON 2018 - 15th International Workshop on Meson Physics. - : EDP Sciences.
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Konferensbidrag (refereegranskat)abstract
- The goal of the P-349 experiment is to test whether 3.5 GeV/c antiprotons produced in high-energy proton-proton collisions are polarized in view of the preparation of a polarized antiproton beam. In this article, we present the details of the ongoing analysis focused on the drift chambers calibration and particle identification with DIRC.
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| 3. |
- Alfs, D., et al.
(författare)
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Status of the analysis for the search of polarization in the antiproton production process
- 2016
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Ingår i: MESON 2016 - 14th International Workshop On Meson Production, Properties And Interaction. - : EDP Sciences.
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Konferensbidrag (refereegranskat)abstract
- The P-349 experiment aims to test whether for antiprotons the production process itself can be a source of polarization in view of the preparation of a polarized antiproton beam. In this article we present the details of performed measurements and report on the status of the ongoing analysis.
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| 4. |
- Grzonka, D., et al.
(författare)
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Polarization analysis of <(p)over bar> produced in pA collisions
- 2019
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Ingår i: MESON 2018 - 15th International Workshop on Meson Physics. - : EDP Sciences.
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Konferensbidrag (refereegranskat)abstract
- A quite simple procedure for the generation of a polarized antiproton beam could be worked out if antiprotons are produced with some polarization. In order to investigate this possibility measurements of the polarization of produced antiprotons have been started at a CERN/PS test beam. The polarization will be determined from the asymmetry of the elastic antiproton scattering at a liquid hydrogen target in the CNI region for which the analyzing power is well known. The data are under analysis and an additional measurement is done in 2018. Details on the experiment and the ongoing data analysis will be given.
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| 5. |
- Grzonka, D., et al.
(författare)
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Search for Polarization Effects in the Antiproton Production Process
- 2015
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Ingår i: Acta Physica Polonica B. - 0587-4254 .- 1509-5770. ; 46:1, s. 191-201
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Tidskriftsartikel (refereegranskat)abstract
- For the production of a polarized antiproton beam, various methods have been suggested including the possibility that antiprotons may be produced polarized which will be checked experimentally. The polarization of antiprotons produced under typical conditions for antiproton beam preparation will be measured at the CERN/PS. If the production process creates some polarization, a polarized antiproton beam could be prepared by a rather simple modification of the antiproton beam facility. The detection setup and the expected experimental conditions are described.
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| 6. |
- Grzonka, D., et al.
(författare)
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Search for polarized antiproton production
- 2019
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Ingår i: Hyperfine Interactions. - : Springer Nature. - 0304-3843 .- 1572-9540. ; 240
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Tidskriftsartikel (refereegranskat)abstract
- The production of antiprotons is studied in view of possible polarization effects as basis for a polarized antiproton beam. If antiprotons are produced with some polarization, a quite simple procedure for the generation of a polarized antiproton beam could be worked out. The experiments are performed at the CERN PS test beam T11 where secondary particles with momenta around 3.5 GeV/c are selected. The polarization analysis is performed by measuring the asymmetry of the elastic (p) over barp-scattering in the Coulomb-nuclear interference region. The detection system includes Cherenkov and tracking detectors for the particle identification and the 3d track reconstruction. Details on the detection system and the status of the analysis are given.
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| 7. |
- Alfs, D., et al.
(författare)
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Drift Chamber Calibration And Track Reconstruction In The P349 Antiproton Polarization Experiment
- 2017
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Ingår i: Acta Physica Polonica B. - 0587-4254 .- 1509-5770. ; 48:10, s. 1983-1988
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Tidskriftsartikel (refereegranskat)abstract
- The goal of the P349 experiment is to test whether the antiproton production process can be itself a source of antiproton polarization. In this article, we present the motivation and details of the performed measurement. We report on the status of the analysis focusing mainly on calibration of the drift chambers and 3d track reconstruction.
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| 8. |
- Morales, Hernán E., 1985, et al.
(författare)
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Concordant divergence of mitogenomes and a mitonuclear gene cluster in bird lineages inhabiting different climates
- 2018
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Ingår i: Nature Ecology & Evolution. - : Springer Science and Business Media LLC. - 2397-334X. ; 2:8, s. 1258-1267
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Tidskriftsartikel (refereegranskat)abstract
- Metabolic processes in eukaryotic cells depend on interactions between mitochondrial and nuclear gene products (mitonuclear interactions). These interactions could have a direct role in population divergence. Here, we study mitonuclear co-evolution in a widespread bird that experienced population divergence followed by bidirectional mitochondrial introgression into different nuclear backgrounds. Using >60,000 single nucleotide polymorphisms, we quantify patterns of nuclear genetic differentiation between populations that occupy areas with different climates and harbour deeply divergent mitochondrial lineages despite ongoing nuclear gene flow. We find that strong genetic differentiation and sequence divergence in a region of similar to 15.4 mega-bases on chromosome 1A mirror the geographic pattern of mitochondrial DNA divergence. This result is seen in two different transects representing populations with different nuclear backgrounds. The chromosome 1A region is enriched for genes performing mitochondrial functions (N-mt genes). Molecular signatures of selective sweeps in this region alongside those in the mitochondrial genome suggest a history of adaptive mitonuclear co-introgression. Moreover, evidence for large linkage disequilibrium blocks in this genomic region suggests that low recombination could facilitate functional interactions between co-evolved nuclear alleles. Our results are consistent with mitonuclear co-evolution as an important mechanism for population divergence and local adaptation.
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| 9. |
- Pourkheirandish, M., et al.
(författare)
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Evolution of the Grain Dispersal System in Barley
- 2015
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Ingår i: Cell. - : Elsevier BV. - 0092-8674. ; 162:3, s. 527-539
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Tidskriftsartikel (refereegranskat)abstract
- About 12,000 years ago in the Near East, humans began the transition from hunter-gathering to agriculture-based societies. Barley was a founder crop in this process, and the most important steps in its domestication were mutations in two adjacent, dominant, and complementary genes, through which grains were retained on the inflorescence at maturity, enabling effective harvesting. Independent recessive mutations in each of these genes caused cell wall thickening in a highly specific grain "disarticulation zone," converting the brittle floral axis (the rachis) of the wild-type into a tough, non-brittle form that promoted grain retention. By tracing the evolutionary history of allelic variation in both genes, we conclude that spatially and temporally independent selections of germplasm with a non-brittle rachis were made during the domestication of barley by farmers in the southern and northern regions of the Levant, actions that made a major contribution to the emergence of early agrarian societies.
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| 10. |
- Bose, R, et al.
(författare)
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Tet3 mediates stable glucocorticoid-induced alterations in DNA methylation and Dnmt3a/Dkk1 expression in neural progenitors
- 2015
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Ingår i: Cell death & disease. - : Springer Science and Business Media LLC. - 2041-4889. ; 6, s. e1793-
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Tidskriftsartikel (refereegranskat)abstract
- Developmental exposure to excess glucocorticoids (GCs) has harmful neurodevelopmental effects, which include persistent alterations in the differentiation potential of embryonic neural stem cells (NSCs). The mechanisms, however, are largely unknown. Here, we investigated the effects of dexamethasone (Dex, a synthetic GC analog) by MeDIP-like genome-wide analysis of differentially methylated DNA regions (DMRs) in NSCs isolated from embryonic rat cortices. We found that Dex-induced genome-wide DNA hypomethylation in the NSCs in vitro. Similarly, in utero exposure to Dex resulted in global DNA hypomethylation in the cerebral cortex of 3-day-old mouse pups. Dex-exposed NSCs displayed stable changes in the expression of the DNA methyltransferase Dnmt3a, and Dkk1, an essential factor for neuronal differentiation. These alterations were dependent on Tet3 upregulation. In conclusion, we propose that GCs elicit strong and persistent effects on DNA methylation in NSCs with Tet3 playing an essential role in the regulation of Dnmt3a and Dkk1. Noteworthy is the occurrence of similar changes in Dnmt3a and Dkk1 gene expression after exposure to excess GC in vivo.
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