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Träfflista för sökning "WFRF:(Knutsson K.) srt2:(2015-2019)"

Sökning: WFRF:(Knutsson K.) > (2015-2019)

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1.
  • 2017
  • swepub:Mat__t
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2.
  • Aad, G, et al. (författare)
  • 2015
  • swepub:Mat__t
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3.
  • Askaner, K., et al. (författare)
  • Differentiation between glioblastomas and brain metastases and regarding their primary site of malignancy using dynamic susceptibility contrast MRI at 3T
  • 2019
  • Ingår i: Journal of Neuroradiology. - : Elsevier BV. - 0150-9861. ; 46:6, s. 367-372
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Differentiation between glioblastoma and brain metastasis may be challenging in conventional contrast-enhanced MRI. Purpose: To investigate if perfusion-weighted MRI is able to differentiate glioblastoma from metastasis and, as a second aim was to see if it was possible in the latter group, to predict the primary site of neoplasm. Material and methods: Hundred and fourteen patients with newly discovered tumor lesion (76 metastases and 38 glioblastomas) underwent conventional contrast-enhanced MRI including dynamic susceptibility contrast perfusion sequence. The calculated relative cerebral blood volumes were analyzed in the solid tumor area, peritumoral area, area adjacent to peritumoral area, and normal appearing white matter in contralateral semioval center. The Student t-test was used to detect statistically significant differences in relative cerebral blood volume between glioblastomas and metastases in the aforementioned areas. Furthermore, the metastasis group was divided in four sub groups (lung-, breast-, melanoma-, and gastrointestinal origin) and using one-way ANOVA test. P-values < 0.05 were considered significant. Results: Relative cerebral blood volume (rCBV) in the peritumoral edema was significantly higher in glioblastomas than in metastases (mean 3.2 ± 1.4 and mean 0.9 ± 0.7), respectively, (P < 0.0001). No significant differences in the solid tumor area or the area adjacent to edema were found, (P = 0.28 and 0.21 respectively). There were no significant differences among metastases in the four groups. Conclusion: It is possible to differentiate glioblastomas from metastases by measuring the CBV in the peritumoral edema. It is not possible to differentiate between brain metastases from different primaries (lung-, breast-, melanoma or gastrointestinal) using CBV-measurements in the solid tumor area, peritumoral edema or area adjacent to edema.
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4.
  • Madsen, I. E. H., et al. (författare)
  • Job strain as a risk factor for clinical depression : systematic review and meta-analysis with additional individual participant data
  • 2017
  • Ingår i: Psychological Medicine. - : Cambridge University Press. - 0033-2917 .- 1469-8978. ; 47:8, s. 1342-1356
  • Forskningsöversikt (refereegranskat)abstract
    • Background. Adverse psychosocial working environments characterized by job strain (the combination of high demands and low control at work) are associated with an increased risk of depressive symptoms among employees, but evidence on clinically diagnosed depression is scarce. We examined job strain as a risk factor for clinical depression. Method. We identified published cohort studies from a systematic literature search in PubMed and PsycNET and obtained 14 cohort studies with unpublished individual-level data from the Individual-Participant-Data Meta-analysis in Working Populations (IPD-Work) Consortium. Summary estimates of the association were obtained using random-effects models. Individual-level data analyses were based on a pre-published study protocol. Results. We included six published studies with a total of 27 461 individuals and 914 incident cases of clinical depression. From unpublished datasets we included 120 221 individuals and 982 first episodes of hospital-treated clinical depression. Job strain was associated with an increased risk of clinical depression in both published [relative risk (RR) = 1.77, 95% confidence interval (CI) 1.47-2.13] and unpublished datasets (RR = 1.27, 95% CI 1.04-1.55). Further individual participant analyses showed a similar association across sociodemographic subgroups and after excluding individuals with baseline somatic disease. The association was unchanged when excluding individuals with baseline depressive symptoms (RR = 1.25, 95% CI 0.94-1.65), but attenuated on adjustment for a continuous depressive symptoms score (RR = 1.03, 95% CI 0.81-1.32). Conclusions. Job strain may precipitate clinical depression among employees. Future intervention studies should test whether job strain is a modifiable risk factor for depression.
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5.
  • Zamora, Juan Carlos, et al. (författare)
  • Considerations and consequences of allowing DNA sequence data as types of fungal taxa
  • 2018
  • Ingår i: IMA Fungus. - : INT MYCOLOGICAL ASSOC. - 2210-6340 .- 2210-6359. ; 9:1, s. 167-185
  • Tidskriftsartikel (refereegranskat)abstract
    • Nomenclatural type definitions are one of the most important concepts in biological nomenclature. Being physical objects that can be re-studied by other researchers, types permanently link taxonomy (an artificial agreement to classify biological diversity) with nomenclature (an artificial agreement to name biological diversity). Two proposals to amend the International Code of Nomenclature for algae, fungi, and plants (ICN), allowing DNA sequences alone (of any region and extent) to serve as types of taxon names for voucherless fungi (mainly putative taxa from environmental DNA sequences), have been submitted to be voted on at the 11th International Mycological Congress (Puerto Rico, July 2018). We consider various genetic processes affecting the distribution of alleles among taxa and find that alleles may not consistently and uniquely represent the species within which they are contained. Should the proposals be accepted, the meaning of nomenclatural types would change in a fundamental way from physical objects as sources of data to the data themselves. Such changes are conducive to irreproducible science, the potential typification on artefactual data, and massive creation of names with low information content, ultimately causing nomenclatural instability and unnecessary work for future researchers that would stall future explorations of fungal diversity. We conclude that the acceptance of DNA sequences alone as types of names of taxa, under the terms used in the current proposals, is unnecessary and would not solve the problem of naming putative taxa known only from DNA sequences in a scientifically defensible way. As an alternative, we highlight the use of formulas for naming putative taxa (candidate taxa) that do not require any modification of the ICN.
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6.
  • Adamo, Nasrat, et al. (författare)
  • Badush Dam : Controversy and Future Possibilities
  • 2018
  • Ingår i: Journal of Earth Sciences and Geotechnical Engineering. - UK : Scientific Press International Limited. - 1792-9040 .- 1792-9660. ; 8:2, s. 17-33
  • Tidskriftsartikel (refereegranskat)abstract
    • Badush Dam is believed to be the first dam in the world which is designed to protect from the flood wave which could result from the collapse of another dam; in this case Mosul Dam.  Badush Dam construction was started in 1988 but it was stopped two years later due to unexpected reasons. From that time on many attempts were made to resume construction without success. Its value was stressed in a multitude of studies and technical reports amid conflict of opinions on how to do this.  The original design of the dam as a protection dam was intended to have a large part of the reservoir empty to accommodate the volume of the expected flood wave for only a few months during which time it’s content are released in a controlled and safe way to the downstream. The lower part of Badush Dam which has a limited height continues before and after this event to act as a low head power generation facility. Among the later studies on the dam, there were suggestions to introduce changes to the design of the unfinished dam which covered the foundation treatment and also asked for constructing a diaphragm in the dam. A long controversy is still going on with many possibilities but with no hope to reach a final solution soon. Any rational solution must consider both Badush Dam and Mosul Dam together as the safety issue involves both of them. This paper may be seen in six paragraphs. The first three describe in brief the history, the outline design and foundation treatment of the dam, therefore, setting the background to follow the conflicting views over its purpose and future which is discussed in the following two paragraphs. The final paragraph is devoted to discussion and our conclusions.
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7.
  • Adamo, Nasrat, et al. (författare)
  • Climate Change : Consequences on Iraq’s Environment
  • 2018
  • Ingår i: Journal of Earth Sciences and Geotechnical Engineering. - London : Scientific Press International Limited. - 1792-9040 .- 1792-9660. ; 8:3, s. 43-58
  • Tidskriftsartikel (refereegranskat)abstract
    • Iraq as a country is now suffering from Climate Change Impacts in similar or even worse ways than many other countries of the world. The manifestations of these climate changes are being felt in global warming, changes to weather driving elements and sea level rise. Increasing temperatures, declining precipitation rates and changed distribution patterns together with increasing evaporation are causing water stress in Iraq. However, they trigger other changes in a sort of chain reaction; such as droughts, desertification and sand storms. Iraq is not even safe from the consequences of sea level rise where the southern part of the Tigris- Euphrates delta is threatened by inundation and Iraq’s ports and sea coast line are endangered by such projected rise. So far the agricultural sector in Iraq has been hit very badly by the reduced water availability for arable lands; whether rain fed lands as in the northern part, or irrigated lands using the declining discharges of the Tigris and Euphrates Rivers as in the southern and middle parts. These discharges have already been additionally strained by the unfair sharing practiced by Turkey from which most of the two rivers’ water resources originate. The present negative climate change trends seem to be continuing in the future as it is obvious from all projections and studies being performed so far. Loss of cultivable land to desertification, recurrent droughts and sand storms and declining agriculture are the pattern of change in Iraq’s already fragile environment; and this will result inevitably in much more distress for the population in the future and will lead to social unrest. These will add to the great pressures facing all future governments unless the government takes protective planning and solutions.
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8.
  • Adamo, Nasrat, et al. (författare)
  • Comparative Study of Mosul and Haditha Dams in Iraq : Different Construction Materials Contribute to Different designs
  • 2018
  • Ingår i: Journal of Earth Sciences and Geotechnical Engineering. - UK : Scientific Press International Limited. - 1792-9040 .- 1792-9660. ; 8:2, s. 71-89
  • Tidskriftsartikel (refereegranskat)abstract
    • Mosul and Haditha Dams are built on relatively weak foundations. Both of these foundations suffer from extensive karsts which had demanded intensive foundation treatment works among other design precautions. The karst forms; however, are of different origins, activities, nature and shapes. The foundation treatment in both dams was done mainly by constructing deep grout curtains along with other secondary grouting works. Reducing uplift pressure under the dam and cutting down on seepage losses were the major considerations in these works. An additional important requirement in Mosul Dam was to reduce the permeability of the rock formation in the foundations to such a low limit that it can stop the dissolution of gypsum beds present there. This objective; unfortunately, failed due to the lithological composition of this foundation and the presence of many brecciated gypsum beds, which could not be treated successfully. This had resulted in a comprehensive grouting maintenance program which continuous up to date with the everlasting danger of dam failure. On the other hand, in Haditha dam no such complication occurs as the dam had its foundations mainly in limestone. Proper investigation and good planning and performance of the grouting works in this dam contributed highly to its success. Selecting the deep grout curtain as anti-seepage measure in Mosul Dam was not a very wise decision and constructing a positive cutoff in the form of diaphragm wall could have been the proper choice. Good and deep understanding of all geological data can contribute to the success of a dam design or, otherwise it may lead to unsafe one.
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9.
  • Adamo, Nasrat, et al. (författare)
  • Comparative Study of Mosul and Haditha Dams, Iraq : Foundation Treatments in the Two Dams
  • 2018
  • Ingår i: Journal of Earth Sciences and Geotechnical Engineering. - UK : Scientific Press International Limited. - 1792-9040 .- 1792-9660. ; 8:2, s. 53-70
  • Tidskriftsartikel (refereegranskat)abstract
    • Mosul and Haditha Dams are built on relatively weak foundations. Both of these foundations suffer from extensive karsts which had demanded intensive foundation treatment works among other design precautions. The karst forms; however, are of different origins, activities, nature and shapes. The foundation treatment in both dams was done mainly by constructing deep grout curtains along with other secondary grouting works. Reducing uplift pressure under the dam and cutting down on seepage losses were the major considerations in these works. An additional important requirement in Mosul Dam was to reduce the permeability of the rock formation in the foundations to such a low limit that it can stop the dissolution of gypsum beds present there. This objective; unfortunately, failed due to the lithological composition of this foundation and the presence of many brecciated gypsum beds, which could not be treated successfully. This had resulted in a comprehensive grouting maintenance program which continuous up to date with the everlasting danger of dam failure. On the other hand, in Haditha dam no such complication occurs as the dam had its foundations mainly in limestone. Proper investigation and good planning and performance of the grouting works in this dam contributed highly to its success. Selecting the deep grout curtain as anti-seepage measure in Mosul Dam was not a very wise decision and constructing a positive cutoff in the form of diaphragm wall could have been the proper choice. Good and deep understanding of all geological data can contribute to the success of a dam design or, otherwise it may lead to unsafe one.
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10.
  • Al-Ansari, Nadhir, et al. (författare)
  • Water Quality within the Tigris and Euphrates Catchments
  • 2018
  • Ingår i: Journal of Earth Sciences and Geotechnical Engineering. - UK : Scientific Press International Limited. - 1792-9040 .- 1792-9660. ; 8:3, s. 95-121
  • Tidskriftsartikel (refereegranskat)abstract
    • Euphrates and Tigris Rivers are the longest two rivers in southwest Asia. The Basins of these rivers cover an area of 917 103 km2 which is occupied by about 46 million inhabitants. Four countries (Turkey, Iran, Iraq and Syria) share the basin area of the Tigris River and the other four (Turkey, Syria, Iraq and Saudi Arabia) share the catchment area of the Euphrates River. The flow of the two rivers is decreasing with time due to construction of dams in the upstream part of the basins and climate change. This has impacted the water quality of the two rivers. Iraq is highly affected followed by Syria. The salinity of Tigris Rivers has become alarming downstream Baghdad while the Euphrates water quality deteriorates before entering the Iraqi border. To overcome water quality deterioration, international, regional and national cooperation is required to reach prudent planning for water resources management of the two basins.
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