| 1. |
- Chapnick, J. V., et al.
(författare)
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Techniques for multimodality image registration
- 1993
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Ingår i: Bioengineering, Proceedings of the Northeast Conference. - 0780309251 ; , s. 221-222
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Konferensbidrag (refereegranskat)abstract
- The authors describe the development of techniques used for cross-modality correlation of medical images. To accomplish this goal, software routines were developed which automate and standardize the comparison of images within and between three-dimensional tomographic imaging modalities. Data from phantoms and clinical studies reflect the success of this technique.
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| 2. |
- Noz, Marilyn E., et al.
(författare)
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Graphical interface for medical image processing
- 1993
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Ingår i: Journal of medical systems. - 0148-5598 .- 1573-689X. ; 17:1, s. 1-16
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Tidskriftsartikel (refereegranskat)abstract
- We have developed a graphical interface which allows users of varying levels of computer experience and proficiency to manipulate medical image-processing data with "point-and-click" ease. The power which had formerly been associated with protocols and shell scripts has been combined with the flexibility and "user-friendliness" of buttons and dialog boxes.
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| 3. |
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| 4. |
- Birnbaum, Bernard A., et al.
(författare)
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Hepatic hemangiomas: diagnosis with fusion of MR, CT, and Tc-99m-labeled red blood cell SPECT images
- 1991
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Ingår i: Radiology. - : Radiological Society of North America. - 0033-8419 .- 1527-1315. ; 181:2, s. 469-474
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Tidskriftsartikel (refereegranskat)abstract
- A method of image analysis was developed for correlation of hemangiomas detected at computed tomography {(CT)} and/or magnetic resonance {(MR)} imaging with increased blood pool activity evident at single photon emission {CT} {(SPECT)} performed after labeling of red blood cells with technetium-99m. Image analysis was performed in 20 patients with 35 known hepatic hemangiomas. After section thickness and pixel sizes of the different studies were matched, intrinsic landmarks were chosen to identify anatomically corresponding locations. Regions of interest {(ROIs)} drawn on the {CT} and/or {MR} images were translated, rotated, and reprojected to match the areas of interest on the corresponding {SPECT} images by means of a two-dimensional polynomial-based warping algorithm. Analysis of {ROIs} on 30 {SPECT-MR} and 20 {SPECT-CT} pairs of registered images provided absolute confirmation that 34 suspected hemangiomas identified on {SPECT} images correlated exactly with lesions seen on {CT} and/or {MR} images. Accuracy of fusion was within an average of 1.5 pixels +/- 0.8 (+/- 1 standard deviation). The technique enabled diagnostic confirmation of hemangiomas as small as 1.0 cm and proved useful for evaluating lesions located adjacent to intrahepatic vessels.
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| 8. |
- Noz, Marilyn E., et al.
(författare)
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An integrated approach to biodistribution radiation absorbed dose estimates
- 1993
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Ingår i: European Journal of Nuclear Medicine. - 0340-6997 .- 1432-105X. ; 20:2, s. 165-169
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Tidskriftsartikel (refereegranskat)abstract
- An integrated approach to existing methods of extracting biodistribution data, pharmacokinetics and radiation absorbed dose estimates from serial scintigraphic images is described. This approach employs a single computer-generated user interface to reformat planar scans into a standard file type, align conjugate (anterior and posterior) images, draw regions of interest {(ROIs)} over selected organs and lesions and generate count data for anterior and posterior views and calculated geometric means. Using standard correction methods, the fraction injected activity is obtained for all {ROIs} and total body. This methodology has been applied to the analysis of {indium-III-labelled} breast-cancer-directed antibodies and technetium-90m-labelled {CEA-specific} antibody fragments in non-small-cell lung cancer. It is anticipated that this approach will be useful for evaluating the dosimetry of other radiolabelled monoclonal antibodies, as well as other radiopharmaceuticals.}
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