| 1. |
- Bolinius, Dämien J., et al.
(författare)
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Evaluating the consumption of chemical products and articles as proxies for diffuse emissions to the environment
- 2018
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Ingår i: Environmental Science. - : Royal Society of Chemistry (RSC). - 2050-7887 .- 2050-7895. ; 20:10, s. 1427-1440
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Tidskriftsartikel (refereegranskat)abstract
- In this study we have evaluated the use of consumption of manufactured products (chemical products and articles) in the EU as proxies for diffuse emissions of chemicals to the environment. The content of chemical products is relatively well known. However, the content of articles (products defined by their shape rather than their composition) is less known and currently has to be estimated from chemicals that are known to occur in a small set of materials, such as plastics, that are part of the articles. Using trade and production data from Eurostat in combination with product composition data from a database on chemical content in materials (the Commodity Guide), we were able to calculate trends in the apparent consumption and in-use stocks for 768 chemicals in the EU for the period 2003-2016. The results showed that changes in the apparent consumption of these chemicals over time are smaller than in the consumption of corresponding products in which the chemicals are present. In general, our results suggest that little change in chemical consumption has occurred over the timespan studied, partly due to the financial crisis in 2008 which led to a sudden drop in the consumption, and partly due to the fact that each of the chemicals studied is present in a wide variety of products. Estimated in-use stocks of chemicals show an increasing trend over time, indicating that the mass of chemicals in articles in the EU, that could potentially be released to the environment, is increasing. The quantitative results from this study are associated with large uncertainties due to limitations of the available data. These limitations are highlighted in this study and further underline the current lack of transparency on chemicals in articles. Recommendations on how to address these limitations are also discussed.
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| 2. |
- Ek, Anna, et al.
(författare)
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A randomized controlled trial for overweight and obesity in preschoolers : the More and Less Europe study – an intervention within the STOP project
- 2019
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Ingår i: BMC Public Health. - : Springer Science and Business Media LLC. - 1471-2458. ; 19
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Childhood overweight and obesity is a serious public health issue with an increase being observed in preschool-aged children. Treating childhood obesity is difficult and few countries use standardized treatments. Therefore, there is a need to find effective approaches that are feasible for both health care providers and families. Thus, the overall aim of this study is to assess the acceptance and effectiveness of a parent support program (the More and Less, ML) for the management of overweight and obesity followed by a mobile health (mHealth) program (the MINISTOP application) in a socially diverse population of families.METHODS/DESIGN: A two-arm, parallel design randomized controlled trial in 300 2-to 6-year-old children with overweight and obesity from Romania, Spain and Sweden (n = 100 from each). Following baseline assessments children are randomized into the intervention or control group in a 1:1 ratio. The intervention, the ML program, consists of 10-weekly group sessions which focus on evidence-based parenting practices, followed by the previously validated MINISTOP application for 6-months to support healthy eating and physical activity behaviors. The primary outcome is change in body mass index (BMI) z-score after 9-months and secondary outcomes include: waist circumference, eating behavior (Child Eating Behavior Questionnaire), parenting behavior (Comprehensive Feeding Practices Questionnaire), physical activity (ActiGraph wGT3x-BT), dietary patterns (based on metabolic markers from urine and 24 h dietary recalls), epigenetic and gut hormones (fasting blood samples), and the overall acceptance of the overweight and obesity management in young children (semi-structured interviews). Outcomes are measured at baseline and after: 10-weeks (only BMI z-score, waist circumference), 9-months (all outcomes), 15- and 21-months (all outcomes except physical activity, dietary patterns, epigenetics and gut hormones) post-baseline.DISCUSSION: This study will evaluate a parent support program for weight management in young children in three European countries. To boost the effect of the ML program the families will be supported by an app for 6-months. If the program is found to be effective, it has the potential to be implemented into routine care to reduce overweight and obesity in young children and the app could prove to be a viable option for sustained effects of the care provided.
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| 3. |
- Enkirch, Theresa, et al.
(författare)
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Hepatitis A outbreak linked to imported frozen strawberries by sequencing, Sweden and Austria, June to September 2018
- 2018
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Ingår i: Eurosurveillance. - : European Centre for Disease Prevention and Control. - 1025-496X .- 1560-7917. ; 23:41
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Tidskriftsartikel (refereegranskat)abstract
- Between June-September 2018, 20 hepatitis A cases were notified in six counties in Sweden. Combined epidemiological and microbiological investigations identified imported frozen strawberries produced in Poland as the source of the outbreak. Sequence analysis confirmed the outbreak strain IB in the strawberries with 100 % identity and the respective batch was withdrawn. Sharing the sequence information internationally led to the identification of 14 additional cases in Austria, linked to strawberries from the same producer.
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| 4. |
- Felton, Adam, et al.
(författare)
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The biodiversity contribution of wood plantations: Contrasting the bird communities of Sweden's protected and production oak forests
- 2016
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Ingår i: Forest Ecology and Management. - : Elsevier BV. - 0378-1127 .- 1872-7042. ; 365, s. 51-60
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Tidskriftsartikel (refereegranskat)abstract
- The oak-dominated woodlands and forests of northern Europe have experienced dramatic declines due to agriculture, urbanization, and conifer-dominated production forestry. These losses have had a substantial negative impact on biodiversity due to the large number of forest species which depend on oak and the environments oak-dominated forests provide. Production oak stands may serve as a means of supplementing or complementing the habitat provided by the limited remaining natural oak remnants in this region. Here we evaluate the extent to which oak plantations in temperate southern Sweden provide habitat and resources for bird communities, by surveying and contrasting the bird species composition and diversity found in mature and young production oak stands (5 and 8 replicates respectively) and protected oak-dominated remnant forests (5 replicates). The mature production stands possessed a bird community partially overlapping in bird species composition, and comparable in species richness (34 species) to that found within protected oak forests (39 species). Furthermore, the production oak forests surveyed hosted threatened or near threatened bird species, including black woodpecker (Dryocopus martius), goldcrest (Regulus regulus), starling (Sturnus vulgaris), and yellowhammer (Emberiza citrinella). Though production oak forests cannot replace the habitat provided by protected oak forests, these stands do appear to provide conditions consistent with the habitat and resource requirements of a diverse cross-section of bird species in this region, including species of substantial conservation concern. Production oak forests thus have the capacity to make a positive contribution to biodiversity conservation, as well as providing a diverse range of goods and services to society. (C) 2016 Elsevier B.V. All rights reserved.
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| 5. |
- Löf, Emma, et al.
(författare)
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Herd and environmental determinants of reproductive performance in Swedish dairy herds, 2001-2009
- 2019
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Ingår i: Spatial and Spatio-temporal Epidemiology. - : Elsevier BV. - 1877-5845 .- 1877-5853. ; 31
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Tidskriftsartikel (refereegranskat)abstract
- This was a retrospective cohort study of Swedish dairy herds. Summary measures of production and reproductive performance, details of soil, moss mineral concentrations, and temperature and rainfall measurements at each herd location were available for the period September 2001 to August 2009. A Bayesian mixed-effects regression model including spatial and non-spatial heterogeneity terms was developed to quantify associations between hypothesised explanatory variables and mean herd breeding interval, defined as the difference between mean calving to last service interval and mean calving to first service interval for each fiscal year.Mean herd breeding intervals were shorter in herds with greater than 80% Swedish Red Cattle, herds with lower mean age at first calving, herds comprised of older cows and in larger herds. None of the soil composition or moss mineral concentration estimates were associated with mean herd breeding interval and the effect of temperature and rainfall on mean herd breeding interval was small. We conclude that environmental conditions (soil composition, moss mineral concentrations, environmental temperature and rainfall) had relatively minor effects on dairy herd reproductive performance in Sweden between 2001 and 2009. (C) 2019 Published by Elsevier Ltd.
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| 6. |
- Löf, Liza, et al.
(författare)
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Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout
- 2016
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 6
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Tidskriftsartikel (refereegranskat)abstract
- Flow cytometry is a powerful method for quantitative and qualitative analysis of individual cells. However, flow cytometric analysis of extracellular vesicles (EVs), and the proteins present on their surfaces has been hampered by the small size of the EVs - in particular for the smallest EVs, which can be as little as 40 nm in diameter, the limited number of antigens present, and their low refractive index. We addressed these limitations for detection and characterization of EV by flow cytometry through the use of multiplex and multicolor in situ proximity ligation assays (in situ PLA), allowing each detected EV to be easily recorded over background noise using a conventional flow cytometer. By targeting sets of proteins on the surface that are specific for distinct classes of EVs, the method allows for selective recognition of populations of EVs in samples containing more than one type of EVs. The method presented herein opens up for analyses of EVs using flow cytometry for their characterization and quantification.
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