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Träfflista för sökning "WFRF:(Löfgren B) srt2:(2005-2009)"

Sökning: WFRF:(Löfgren B) > (2005-2009)

  • Resultat 1-9 av 9
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  • Löfgren, Linus, et al. (författare)
  • Low-power humidity sensor for RFID applications
  • 2008
  • Ingår i: 4M2008 Conference, Cardiff, UK.
  • Konferensbidrag (refereegranskat)abstract
    • Wireless sensors incorporated in RFID systems are important in several industrial, consumer and logisticsapplications. By extending RFID tags to sensing applications, the products become smarter. Application areas forthese smart tags include; health care (verification of the environmental conditions during transport or in storage of e.g.diapers, bandages, etc.), food monitoring (food quality during transport, storage and sales) and construction industry(e.g. building material).In this paper, a small, very low power and low cost humidity sensor tailor made for passive RFID applications ispresented. The sensor consists of a glass chip substrate with a sub-micron interdigitated gold electrode structurecovered with a humidity sensitive polyimide layer. The humidity absorbed by the sensing layer is measuredcapacitively. Finite element modeling and analytic calculations were used to determine the design of the interdigitatedelectrodes and the optimal thickness of the polyimide layer. A read-out electronics circuit was designed and used toevaluate the sensor. Sensors were fabricated and calibrations have been made to verify their function. The sensorresponse was close to linear from below 20 to above 90 %RH and its response time was proven to be at least as shortas that of the climate chamber, namely 0.1 %RH/s. The concept can easily be adapted to measure a range of otherparameters such as temperature or the presence of certain substances.
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  • Strindhall, J, et al. (författare)
  • No Immune Risk Profile among individuals who reach 100 years of age: findings from the Swedish NONA immune longitudinal study
  • 2007
  • Ingår i: Exp Gerontol.. ; 42:8, s. 753-761
  • Tidskriftsartikel (refereegranskat)abstract
    • In the present NONA immune longitudinal study, we investigate the previously identified Immune Risk Profile (IRP), defined by an inverted CD4/CD8 ratio and associated with persistent cytomegalovirus infection and increased numbers of CD8+CD28- cells, relative 6-year survival and age in NONA individuals. These subjects have now reached age 92, 96, and for the first time in this study, 100 years at follow-up. A 55 year old middle-aged group was used for comparison. Immunological monitoring included the analysis of numbers of lymphocytes and neutrophils, the T-cell subsets CD3+CD4+, CD3+CD8+, CD8+CD28+, CD8+CD28-, and the CD4/CD8 ratio. Longitudinal data were analysed by multivariate analyses of variance (MANOVA) from four measurement occasions at 2-year inter-intervals. One-way ANOVA was used for cross-sectional comparisons at baseline and the 6-year follow-up. The results confirmed the importance of the IRP as a major predictor of mortality in this population of very old. Moreover, the results suggested that survival to the age of 100 years is associated with selection of individuals with an "inverted" IRP that was stable across time, i.e., maintenance of a high CD4/CD8 ratio and low numbers of CD8+CD28- cells. The results underlines the importance of a longitudinal study design in dissecting immune parameters predictive of survival and show for the first time that centenarian status is associated with avoidance of the IRP over at least the previous 6 years and probably throughout life.
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  • Wikby, A, et al. (författare)
  • An immune risk phenotype, cognitive impairment and survival in very late life: The impact of alosta-tic load in Swedish Octo- and Nongenarian humans
  • 2005
  • Ingår i: Journal Gerontology: Biological Science. ; , s. 556-565
  • Tidskriftsartikel (refereegranskat)abstract
    • In the previous OCTO longitudinal study, we identified an immune risk pheno-type (IRP) of high CD8 and low CD4 numbers and poor proliferative response. We also demonstrated that cognitive impairment constitutes a major predictor of nonsurvival. In the present NONA longitudinal study, we simultaneously exam-ine in a model of allostatic load IRP and compromised cognition in 4-year survival in a population-based sample (n = 138, 86-94 years). Immune system measure-ments consisted of determinations of T-cell subsets, plasma interleukin 6 and cy-tomegalovirus and Epstein-Barr virus serology. Interleukin 2 responsiveness to concanavalin A, using data from the previous OCTO (octogenarians) immune study, hereafter OCTO immune, was also examined. Cognitive status was rated using a battery of neuropsychological tests. Logistic regression indicated that the IRP and cognitive impairment together predicted 58% of observed deaths. IRP was associated with late differentiated CD8+CD28-CD27- cells (p < .001), de-creased interleukin 2 responsiveness (p < .05) and persistent viral infection (p < .01). Cognitive impairment was associated with increased plasma interleukin 6 (p < .001). IRP individuals with cognitive impairment were all deceased at the fol-low-up, indicating an allostatic overload.
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