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- Dunham, I, et al.
(författare)
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The DNA sequence of human chromosome 22
- 1999
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 402:6761, s. 489-495
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Tidskriftsartikel (refereegranskat)
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- Lai, S.J., et al.
(författare)
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A simulation model of adaptive protocols in distributed computing systems with mobile hosts
- 1995
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Ingår i: Proceedings of the 28th Annual Simulation Symposium. - Los Alamitos, Calif : IEEE Communications Society. - 0818670916 ; , s. 220-227
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Konferensbidrag (refereegranskat)abstract
- Simulation is a scientific method which is largely dominated by computers and has allowed the testing and assessment of many models before actual implementation. The paper proposes an approach to construction of a simulation that models the behaviour of an adaptive queuing protocol (AQP). AQP was developed for database applications on mobile computers in a distributed multidatabase environment but can also be used in many other areas including distributed operating systems. By constructing the simulation model it is possible to both prove that it can be implemented, and at the same time study its expected behaviour in a mobile computing environment. The results of the simulation are analysed and discussed
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- Marincola, F.C., et al.
(författare)
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Recognition and characterization of binding modes of Δ- and Λ-[Ru(phen)3]2+ and Δ- and Λ-[Ru(phen)2DPPZ]2+ by the 23Na NMR Relaxation and Binding Free Energy Parameters
- 1998
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Ingår i: Chemical Physics. - 0301-0104. ; 236:1-3, s. 301-308
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Tidskriftsartikel (refereegranskat)abstract
- Na-23 NMR relaxation rates were measured in Na-DNA aqueous solutions in the presence of Delta- or Lambda-enantiomer of [Ru(phen)(3)](2+) and [Ru(phen)(2)DPPZ](2+). From the analysis of the spin-lattice and spin-spin relaxation rates evidence is given that a decrease of the quadrupolar coupling constant for the slow motions occurs, due to the structural and dynamical modifications of DNA induced by the binding of the ruthenium complexes. Furthermore a linear dependence between the changes of the broad component, R-2bB, and the relative polyelectrolyte contributions to the binding free energy, Delta G(pe)/Delta G, was found. In particular for the intercalators Delta- and Lambda-[Ru(phen)(2)DPPZ](2+), a direct dependence on Delta G(pe)/Delta G was observed, as already found for ethidium, propidium and dq2pyp; while [Ru(phen)(3)](2+) complexes and the pure electrostatic Mg2+ showed an inverse dependence. These results have been discussed in terms of the polyelectrolyte interactions responsible for the R-2bB changes.
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