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- Abarenkov, Kessy, et al.
(författare)
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The UNITE database for molecular identification and taxonomic communication of fungi and other eukaryotes: sequences, taxa and classifications reconsidered
- 2024
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Ingår i: Nucleic Acids Research. - 0305-1048 .- 1362-4962. ; 52:D1, s. D791-D797
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Tidskriftsartikel (refereegranskat)abstract
- UNITE (https://unite.ut.ee) is a web-based database and sequence management environment for molecular identification of eukaryotes. It targets the nuclear ribosomal internal transcribed spacer (ITS) region and offers nearly 10 million such sequences for reference. These are clustered into similar to 2.4M species hypotheses (SHs), each assigned a unique digital object identifier (DOI) to promote unambiguous referencing across studies. UNITE users have contributed over 600 000 third-party sequence annotations, which are shared with a range of databases and other community resources. Recent improvements facilitate the detection of cross-kingdom biological associations and the integration of undescribed groups of organisms into everyday biological pursuits. Serving as a digital twin for eukaryotic biodiversity and communities worldwide, the latest release of UNITE offers improved avenues for biodiversity discovery, precise taxonomic communication and integration of biological knowledge across platforms. Graphical Abstract
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| 2. |
- Borrelli, Pablo, et al.
(författare)
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Artificial intelligence-based detection of lymph node metastases by PET/CT predicts prostate cancer-specific survival
- 2021
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Ingår i: Clinical Physiology and Functional Imaging. - : Wiley. - 1475-0961 .- 1475-097X. ; 41:1, s. 62-67
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Tidskriftsartikel (refereegranskat)abstract
- Introduction Lymph node metastases are a key prognostic factor in prostate cancer (PCa), but detecting lymph node lesions from PET/CT images is a subjective process resulting in inter-reader variability. Artificial intelligence (AI)-based methods can provide an objective image analysis. We aimed at developing and validating an AI-based tool for detection of lymph node lesions. Methods A group of 399 patients with biopsy-proven PCa who had undergone(18)F-choline PET/CT for staging prior to treatment were used to train (n = 319) and test (n = 80) the AI-based tool. The tool consisted of convolutional neural networks using complete PET/CT scans as inputs. In the test set, the AI-based lymph node detections were compared to those of two independent readers. The association with PCa-specific survival was investigated. Results The AI-based tool detected more lymph node lesions than Reader B (98 vs. 87/117;p = .045) using Reader A as reference. AI-based tool and Reader A showed similar performance (90 vs. 87/111;p = .63) using Reader B as reference. The number of lymph node lesions detected by the AI-based tool, PSA, and curative treatment was significantly associated with PCa-specific survival. Conclusion This study shows the feasibility of using an AI-based tool for automated and objective interpretation of PET/CT images that can provide assessments of lymph node lesions comparable with that of experienced readers and prognostic information in PCa patients.
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| 3. |
- Larsson, Allan, 1938-
(författare)
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Climate Transition in Cities : A Swedish Governance Model to Accelerate the Rate of Transition
- 2023
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Rapport (populärvet., debatt m.m.)abstract
- This report has been commissioned by Vinnova within the framework of the Viable Citiesprogramme.The report has two main aims:Firstly, to provide a policy-relevant overview of two new elements for sustainable urbandevelopment: new forms of governance for leading, managing and executing urbanplanning projects, and new forms for supporting innovations in the form of systemsaltering missions rather than a variety of small projects.Secondly, it also aims to help evolve these experiences and lessons learned, with anemphasis on new forms of governance for climate transition in cities and municipalities.The report has been prepared alongside a team of scientists, experts and practitioners.Professor Emeritus Örjan Svane, KTH Royal Institute of Technology, has contributedresearch perspectives on new forms of governance for climate transition. During theprocess, Vinnova and Viable Cities have arranged seminars on the financing of ClimateInvestment Plans, and on digitalization. The report has been sent for referral to the23 municipalities who signed Climate City Contract 2030, and to six government agencies:Formas, Vinnova (the Swedish Agency for Innovation Systems), the Swedish EnergyAgency, the Swedish Agency for Economic and Regional Growth, the Swedish TransportAdministration and the Swedish Environmental Protection Agency. Maria Tengvard, ViableCities, is the editor.
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| 4. |
- Larsson, Allan, 1938-
(författare)
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Klimatomställning av städer : En svensk governance-modell för att öka takten i omställningen
- 2023
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Rapport (populärvet., debatt m.m.)abstract
- Denna rapport har utarbetats på uppdrag av Vinnova inom ramen för programmetViable Cities. Den har två syften.Den ska ge en policyrelevant översikt över två nya element för hållbarstadsutveckling, dels nya former av governance för att leda, styra och genomförastadsbyggnadsprojekt, dels nya former för att stödja innovationer i form avsystemförändrande missioner i stället för många små projekt.Den ska dessutom bidra till att vidareutveckla dessa erfarenheter och lärdomar medinriktning på nya former för governance för klimatomställning i städer och kommuner.Rapporten har arbetats fram med hjälp av ett team av forskare, experter och praktiker.Professor emeritus Örjan Svane, KTH, har bidragit med forskarperspektiv på nya formerav governance för klimatomställning. Han har dessutom skrivit bilaga 1. Jörgen Lööf harbidragit till bilaga 2. Bilaga 3, 4 och 5 har skrivits av Viable Cities team (Olga Kordas, LenaHolmberg, Åsa Minoz m.fl.) med bidrag av Julio Lumbreras, Madrids Tekniska Universitet(UPM). Bilaga 6 har skrivits av Fedra Vanhuyse, Viable Cities och Stockholm EnvironmentInstitute. Vinnova och Viable Cities har under processen ordnat seminarier om finansieringkopplat till klimatinvesteringsplaner samt om digitalisering. Rapporten har sänts påremiss till de 23 kommuner som har undertecknat Klimatkontrakt 2030 samt till sexstatliga myndigheter: Formas, Vinnova, Energimyndigheten, Tillväxtverket, Trafikverketoch Naturvårdsverket.
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