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- Engelson, Vadim, 1965-, et al.
(författare)
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A design, simulation and visualization environment for object-oriented mechanical and multi-domain models in Modelica
- 1999
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Ingår i: 1999 IEEE International Conference on Information Visualization, Proceedings. - 0769502105 ; , s. 188-193
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Konferensbidrag (refereegranskat)abstract
- The complexity of mechanical and multi-domain simulation models is rapidly increasing. Therefore new methods and standards are needed for model design. A new language, Modelica, has been proposed by an international design committee as a standard, object oriented, equation based language suitable for description of the dynamics of systems containing mechanical, electrical, chemical and other types of components. However, it is complicated to describe the system models in textual form, whereas CAD systems are convenient tools for this purpose. We have designed an environment that supports the translation from CAD models to standard Modelica notation. This notation is then used for simulation and visualization. Assembly information is extracted from the CAD models, from which a Modelica model is generated. By solving equations expressed in Modelica, the system is simulated. A 3D visualization tool based on OpenGL visualizes expected and actual model behavior, as well as additional parameters. The environment has been applied for robot and flight simulation
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- Erkfeldt, Sara U, 1974, et al.
(författare)
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Sulphur poisoning and regeneration of NOx trap catalyst for direct injected gasoline engines
- 1999
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Ingår i: Society of Automotive Engineers Technical Paper Series. - 400 Commonwealth Drive, Warrendale, PA, United States : SAE International. ; 1999:SP-1476, s. 51-62
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Tidskriftsartikel (refereegranskat)abstract
- Sulphur poisoning and regeneration of NOx trap catalysts have been studied in synthetic exhausts and in an engine bench. Sulphur gradually poisoned the NO x storage sites in the axial direction of the NO x trap. During sulphur regenerations, hydrogen was found to be more efficient than carbon monoxide in removing the sulphur from the trap. The sulphur regeneration became more efficient the richer the environment (λ
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- Furmark, Tomas, et al.
(författare)
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The amygdala and individual differences in human fear conditioning
- 1997
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Ingår i: NEUROREPORT. - : LIPPINCOTT WILLIAMS & WILKINS. - 0959-4965. ; 8:18, s. 3957-3960
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Tidskriftsartikel (refereegranskat)abstract
- WHILE animal research on fear conditioning suggests crucial involvement of the amygdala, this has not been corroborated in humans when using subtractive neuroimaging methodology. Correlation analyses might be more able to reveal relations between individ
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- Gestblom, C, et al.
(författare)
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The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas
- 1999
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Ingår i: Laboratory Investigation. - 1530-0307 .- 0023-6837. ; 79, s. 67-
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Tidskriftsartikel (refereegranskat)abstract
- Neuroblastoma is derived from the sympathetic nervous system and might arise as a result of impaired differentiation, retaining the neuroblastic tumor cells in the cell cycle. Thus, to understand the genesis of neuroblastoma, the study of mechanisms and genes regulating normal sympathetic development is of potential interest. The basic helix-loop-helix transcription factors human achaete-scute homolog-1 (HASH-1) and deciduum, heart, autonomic nervous system, and neural crest derivatives (dHAND) are expressed in the sympathetic nervous system of embryonic mice and chicken, with undetectable postnatal expression. By in situ hybridization technique, we show that dHAND was expressed by human sympathetic neuronal and extra-adrenal chromaffin cells throughout embryonic and fetal life, and was initially expressed in immature chromaffin cells of the adrenal gland. With overt chromaffin differentiation, dHAND was down-regulated. HASH-1, in contrast, was expressed in human sympathetic cells only at the earliest embryonic ages examined (Week 6.5 to 7). All examined neuroblastoma specimens (25/25) and all cell lines (5/5) had detectable dHAND mRNA levels. HASH-1 expression in tumor specimens was more restricted, although all cell lines (5/5) were HASH-1-positive. These results show that neuroblastoma tumors have retained embryonic features, suggesting that many neuroblastomas are blocked at an early stage of normal development when HASH-1 and dHAND are expressed. dHAND also appears to be a reliable and potentially useful clinical diagnostic marker for neuroblastoma, because expression was not dependent on tumor or differentiation stages and other pediatric tumors were dHAND-negative.
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