| 1. |
- Berglund, Per, et al.
(författare)
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Linking Education and Research : A Roadmap for Higher Education Institutions at the Dawn of the Knowledge Society
- 2019
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Ingår i: Linking education and research. - Basel, Switzerland : MDPI. ; , s. 11-33
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- In an era characterized by a move towards a “knowledge society”, universities are central in fostering “knowledgeability”, that is the reflexive understanding of knowledge in knowledge societies. The objective of “knowledgeability” can be met through creating a stronger link between education and research. Furthermore, overall student performance, for example in critical thinking and problem solving, can be improved if research-related activities are incorporated into the curriculum.The aim of this paper is to use international examples to discuss the research- education nexus from four different perspectives, namely context, policy, implementation and quality, with case studies from higher education institutions in Singapore and Sweden.We suggest that different integrative technologies can be used to enhance the links, but it will be essential to consider the inputs of training, service and support in using new technology. Interestingly, the act of evaluating the link between education and research will increase awareness of this linkage by stakeholders involved in both education and research. In turn the link can be strengthened, contributing to increased quality in both education and research.
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| 2. |
- Broche, Ludovic, et al.
(författare)
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Dynamic Mechanical Interactions Between Neighboring Airspaces Determine Cyclic Opening and Closure in Injured Lung
- 2017
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Ingår i: Critical Care Medicine. - 0090-3493 .- 1530-0293. ; 45:4, s. 687-694
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Positive pressure ventilation exposes the lung to mechanical stresses that can exacerbate injury. The exact mechanism of this pathologic process remains elusive. The goal of this study was to describe recruitment/derecruitment at acinar length scales over short-time frames and test the hypothesis that mechanical interdependence between neighboring lung units determines the spatial and temporal distributions of recruitment/derecruitment, using a computational model. Design: Experimental animal study. Setting: International synchrotron radiation laboratory. Subjects: Four anesthetized rabbits, ventilated in pressure controlled mode. Interventions: The lung was consecutively imaged at - 1.5-minute intervals using phase-contrast synchrotron imaging, at positive end expiratory pressures of 12, 9, 6, 3, and 0 cm H2O before and after lavage and mechanical ventilation induced injury. The extent and spatial distribution of recruitment/derecruitment was analyzed by subtracting subsequent images. In a realistic lung structure, we implemented a mechanistic model in which each unit has individual pressures and speeds of opening and closing. Derecruited and recruited lung fractions (F-derecruaed, F-recruited) were computed based on the comparison of the aerated volumes at successive time points. Measurements and Main Results: Alternative recruitment/derecruitment occurred in neighboring alveoli over short-time scales in all tested positive end-expiratory pressure levels and despite stable pressure controlled mode. The computational model reproduced this behavior only when parenchymal interdependence between neighboring acini was accounted for. Simulations closely mimicked the experimental magnitude of F-derecruited and F-recruited when mechanical interdependence was included, while its exclusion gave F-recruited values of zero at positive end -expiratory pressure greater than or equal to 3 cm H2O. Conclusions: These findings give further insight into the microscopic behavior of the injured lung and provide a means of testing protective-ventilation strategies to prevent recruitment/derecruitment and subsequent lung damage.
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| 3. |
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| 4. |
- Broche, Ludovic, et al.
(författare)
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Individual Airway Closure Characterized In Vivo by Phase-Contrast CT Imaging in Injured Rabbit Lung
- 2019
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Ingår i: Critical Care Medicine. - : LIPPINCOTT WILLIAMS & WILKINS. - 0090-3493 .- 1530-0293. ; 47:9, s. E774-E781
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Airway closure is involved in adverse effects of mechanical ventilation under both general anesthesia and in acute respiratory distress syndrome patients. However, direct evidence and characterization of individual airway closure is lacking. Here, we studied the same individual peripheral airways in intact lungs of anesthetized and mechanically ventilated rabbits, at baseline and following lung injury, using high-resolution synchrotron phase-contrast CT.Design: Laboratory animal investigation.Setting: European synchrotron radiation facility.Subjects: Six New-Zealand White rabbits.Interventions: The animals were anesthetized, paralyzed, and mechanically ventilated in pressure-controlled mode (tidal volume, 6 mL/kg; respiratory rate, 40; Fio(2), 0.6; inspiratory:expiratory, 1:2; and positive end-expiratory pressure, 3 cm H2O) at baseline. Imaging was performed with a 47.5 x 47.5 x 47.5 mu m voxel size, at positive end-expiratory pressure 12, 9, 6, 3, and 0 cm H2O. The imaging sequence was repeated after lung injury induced by whole-lung lavage and injurious ventilation in four rabbits. Cross-sections of the same individual airways were measured.Measurements and Main Results: The airways were measured at baseline (n = 48; radius, 1.7 to 0.21 mm) and after injury (n = 32). Closure was observed at 0 cm H2O in three of 48 airways (6.3%; radius, 0.350.08 mm at positive end-expiratory pressure 12) at baseline and five of 32 (15.6%; radius, 0.28 +/- 0.09 mm) airways after injury. Cross-section was significantly reduced at 3 and 0 cm H2O, after injury, with a significant relation between the relative change in cross-section and airway radius at 12 cm H2O in injured, but not in normal lung (R = 0.60; p < 0.001).Conclusions: Airway collapsibility increases in the injured lung with a significant dependence on airway caliber. We identify "compliant collapse" as the main mechanism of airway closure in initially patent airways, which can occur at more than one site in individual airways.
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| 6. |
- Kianian, Babak, et al.
(författare)
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The Adoption of Additive Manufacturing Technology in Sweden
- 2015
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Ingår i: 3D Printing and Additive Manufacturing. - : Mary Ann Liebert. - 2329-7662 .- 2329-7670. ; 2:4, s. 152-158
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Tidskriftsartikel (refereegranskat)abstract
- This article analyzes the adoption of additive manufacturing (AM) technologies in Sweden. The data set consists of a recent and representative sample of Swedish AM users (companies, universities, and research institutes). The authors investigate two questions. First, what are the current applications of AM in Sweden (e.g., rapid prototyping [RP], production)? Second, what are the factors that can explain the variation in AM adoption among the users? Using a regression analysis technique, the main findings are as follows. (i) There is a variation among users' choice of AM application, and the majority of users are expanding their AM applications beyond RP. (ii) There are two factors that positively affect the decision of firms to expand classical RP and incorporate production and management as well. These two factors are using multiple AM technologies (as opposed to single fused deposition modeling technology) being small companies. The authors discuss the implication of these results.
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| 7. |
- Kianian, Babak, et al.
(författare)
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The Adoption of Additive Manufacturing Technology in Sweden
- 2016
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Ingår i: 13th Global Conference on Sustainable Manufacturing - Decoupling Growth from Resource Use 2015. - : Elsevier BV. - 2212-8271. - 9781510820722 ; 40, s. 7-12, s. 7-12
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Konferensbidrag (refereegranskat)abstract
- This paper analyzes the adoption of Additive Manufacturing (AM) technologies in Sweden. The dataset consists of a recent and representative sample of Swedish AM users (companies, universities, and research institutes). The authors investigate two questions. Firstly, what are the current applications of AM in Sweden (e.g. Rapid Prototyping (RP), production)? Secondly, what are the factors that can explain the variation in AM adoption among the users? Using a regression analysis technique, the main findings are as follows. (i) There is a variation among users' choice of AM application, and the majority of users are expanding their AM applications beyond RP. (ii) There are two factors that positively affect the decision of firms to expand classical RP and also incorporate production and management. These two factors are using multiple AM technologies (as opposed to single Fused Deposition Modeling technology) and being small companies. The authors discuss the implication of these results.
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| 8. |
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| 9. |
- Kianian, Babak, 1985-, et al.
(författare)
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The Role of Additive Manufacturing Technology in job creation : an exploratory case study of suppliers of Additive Manufacturing in Sweden
- 2015
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Ingår i: Procedia CIRP. - : Elsevier. ; , s. 93-98
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Konferensbidrag (refereegranskat)abstract
- his paper investigates how Additive Manufacturing (AM) technologies, as a process innovation, may contribute to a job creation. Further, the various mechanisms in which AM may contribute to an increase in job creation as well as the types of jobs are analyzed. The analysis also goes beyond AM technologies and incorporates other non-technological factors which foster job creation, i.e. higher wages in BRIC countries, lower quality in BRIC countries, and a rising demand for western-made products. The analysis is based on a case study and the data collected was through interviews with three prominent actors within the AM technologies field in Sweden: technology developers, leading suppliers and users. The main findings indicate that AM (i) contributes to job creation in both the manufacturing sector and in the service sector, (ii) does not bring back mass production jobs from emerging economies such as BRIC, (iii) contributes to job creation in product development stages (e.g. rapid prototyping), and (iv) contributes to job creation in production stages of low-volume batches mainly of complex products. The findings also suggest there are barriers for full exploitation of AM in several areas, including education systems.
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