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- Lee, Tzu-Lun, et al.
(författare)
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Prolongation in Mandari
- 2004
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Ingår i: Proceedings of Interspeech (ICSLP) 2004. ; , s. 2181-2184
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Konferensbidrag (refereegranskat)abstract
- This paper presents a corpus-based study on prolongations inspontaneous Mandarin. Prolongations are mainly produced forhesitation, but also for emphasizing a discourse focus and signalling an explicit feedback. 786 prolongation occurrences are investigated in terms of the position, the part of speech andthe segment and tone types. Prolongations are often found in word-final, phrase-final and utterance-medial positions. It is more likely to prolong in function words than in content words.However, in the case of monosyllabic words prolongations are more frequently found in function words, but in the remaining cases prolongations are more likely to be found in content words. Prolongations in transitive verbs, adverbs, nouns andparticles show particularly high rates, while prolongations inintransitive verbs and aspectual adverbs are really rare. Especially, there is no prolonged adjective. Consonants arerarely prolonged in Mandarin and no particular effect is found for lexical tones.
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| 2. |
- Lee, YA, et al.
(författare)
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Genomewide scan in german families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13
- 2000
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Ingår i: American Journal of Human Genetics. - : Elsevier. - 0002-9297 .- 1537-6605. ; 67:4, s. 1020-1024
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Tidskriftsartikel (refereegranskat)abstract
- Psoriasis is a common chronic inflammatory skin disease with a strong genetic component. Few psoriasis-susceptibility loci have been reported, and only two have been confirmed in independent data sets. This article reports results of a genomewide scan that was performed, using 370 microsatellite markers, for psoriasis-susceptibility loci in 32 German extended families, comprising 162 affected and 195 unaffected individuals. Nonparametric linkage analysis of all families provided strong evidence for a novel psoriasis-susceptibility locus on chromosome 19p (Zlr=3.50; P=.0002). Parametric analysis revealed a heterogeneity LOD score of 4.06, corresponding to a genomewide significance level of.037, under the assumption of a recessive model with high disease-allele frequency and 66% as the proportion of linked families. This study confirms linkage of psoriasis to the HLA region on chromosome 6p and suggests additional regions on chromosomes 8q and 21q for further investigations.
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