| 1. |
- Feng, Chungang, et al.
(författare)
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A cis-Regulatory Mutation of PDSS2 Causes Silky-Feather in Chickens
- 2014
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Ingår i: PLOS Genetics. - : Public Library of Science (PLoS). - 1553-7390 .- 1553-7404. ; 10:8, s. e1004576-
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Tidskriftsartikel (refereegranskat)abstract
- Silky-feather has been selected and fixed in some breeds due to its unique appearance. This phenotype is caused by a single recessive gene (hookless, h). Here we map the silky-feather locus to chromosome 3 by linkage analysis and subsequently fine-map it to an 18.9 kb interval using the identical by descent (IBD) method. Further analysis reveals that a C to G transversion located upstream of the prenyl (decaprenyl) diphosphate synthase, subunit 2 (PDSS2) gene is causing silky-feather. All silky-feather birds are homozygous for the G allele. The silky-feather mutation significantly decreases the expression of PDSS2 during feather development in vivo. Consistent with the regulatory effect, the C to G transversion is shown to remarkably reduce PDSS2 promoter activity in vitro. We report a new example of feather structure variation associated with a spontaneous mutation and provide new insight into the PDSS2 function.
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| 2. |
- Weinstein, John N., et al.
(författare)
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The cancer genome atlas pan-cancer analysis project
- 2013
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 45:10, s. 1113-1120
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Tidskriftsartikel (refereegranskat)abstract
- The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. © 2013 Nature America, Inc. All rights reserved.
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| 3. |
- Li, Fei, et al.
(författare)
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A quantum search based signal detection for MIMO-OFDM systems
- 2011
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Ingår i: 18th International Conference on Telecommunications, ICT 2011. - : IEEE. - 9781457700248 - 9781457700255 ; , s. 276-281
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Konferensbidrag (refereegranskat)abstract
- Multiple input multiple output-orthogonal frequency division multiplexing (MIMO-OFDM) is considered as candidates for future broadband wireless services. In this paper a novel signal detection scheme based on Grover's quantum search algorithm is proposed for MIMO-OFDM systems. Grover's quantum search algorithm is based on the concept and principles of quantum computing, such as quantum bit, quantum register and quantum parallelism. An analysis is given to the theoretical basis of Grover's algorithm and the performance of Grover's algorithm is evaluated. A novel signal detector based on Grover's algorithm (GD) for MIMO-OFDM system is proposed. The simulation results show that the proposed detector has more powerful properties in bit error rate than MMSE detector and VBLAST-MMSE detector. The performance of the proposed GD detector is close to optimal when the failure probability is 0.001. When the failure probability is 0.00001, the performance of GD detector declines. In this case, our proposed improved Grover's algorithm based detector is still close to the optimal ML detector. The complexity of GD and IGD is O(√N). It's much better than classical ML detector which complexity is O(N).
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| 4. |
- Li, Fei, et al.
(författare)
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Highly efficient oxidation of water by a molecular catalyst immobilized on carbon nanotubes
- 2011
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Ingår i: Angewandte Chemie International Edition. - : Wiley. - 1433-7851 .- 1521-3773. ; 50:51, s. 12276-12279
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Tidskriftsartikel (refereegranskat)abstract
- A successful team: A molecular device based on multiwalled carbon nanotubes functionalized by a mononuclear ruthenium catalyst has been shown to split water electrochemically (see picture; ITO=indium tin oxide). The readily prepared electrode showed excellent electrocatalytic activity for the oxidation of water, a high current density, and a low overpotential, and constitutes one step forward in the design of artificial photosynthetic systems.
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| 5. |
- Jiang, Yi, et al.
(författare)
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Promoting the Activity of Catalysts for the Oxidation of Water with Bridged Dinuclear Ruthenium Complexes
- 2013
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Ingår i: Angewandte Chemie International Edition. - : Wiley. - 1433-7851 .- 1521-3773. ; 52:12, s. 3398-3401
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Tidskriftsartikel (refereegranskat)abstract
- Solar fuels: Dinuclear ruthenium catalysts prepared from two covalently bridged monomeric catalytic units show outstanding activities towards the oxidation of water with high turnover numbers up to 43 000 and turnover frequencies up to 40 s-1 (see picture). Direct comparison of the performance parameters indicates that the dimers are significantly more active as catalysts than the monomers.
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| 6. |
- Li, Fei, et al.
(författare)
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A novel neural network optimized by quantum genetic algorithm for signal detection in MIMO-OFDM systems
- 2011
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Ingår i: Computational Intelligence in Control and Automation (CICA). - : IEEE. - 9781424499038 - 9781424499021 ; , s. 170-177
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Konferensbidrag (refereegranskat)abstract
- Neural networks can easily fall into a local extremum and have slow convergence rate. Quantum Genetic Algorithm (QGA) has features of small population size and fast convergence. Based on the investigation of QGA, we propose a novel neural network model, Radial Basis Function (RBF) networks optimized by Quantum Genetic Algorithm (QGA-RBF model). Then we investigate the performance of the proposed QGA-RBF on solving MIMO-OFDM signal detection problem. A novel signal detector based on QGA-RBF for MIMO-OFDM system is also proposed. The simulation results show that the proposed detector has more powerful properties in bit error rate than QGA based detector, RBF based detector and MMSE algorithm based detector, namely a 4-6 dB gain in performance can be achieved. The performance of the proposed detector is closer to optimal, compared with the other detectors.
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| 7. |
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| 8. |
- Li, Fei, et al.
(författare)
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Cognitive radio spectrum sharing using improved Quantum Genetic Algorithm
- 2011
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Ingår i: 2011 International Conference on Wireless Communications and Signal Processing, WCSP 2011. - : IEEE. - 9781457710100 - 9781457710094
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Konferensbidrag (refereegranskat)abstract
- A key challenge in cognitive radios (CR) network is how to adaptively and efficiently allocate transmission powers and spectrum among CR users according to the surrounding environment. In this paper, we propose a novel spectrum sharing based on our improved Quantum Genetic Algorithm (QGA) in a non-cooperative game for CR network. We improved the original QGA by quantum crossover operator, in order to overcome the shortcoming of the original QGA easily falling into a local extremum when used to optimize the continuous functions with many extrema. We used our improved QGA as a competitive strategy and conducted several simulations in two-user system and multi-user system. From simulation results, it is evident that the proposed improved QGA based spectrum sharing scheme has better convergence rate and higher sum capacity than GA based scheme even in multi-user CR system, namely up to 2bit/s/Hz increase in capacity. The simulation results also show that the population size of QGA affect sum capacity of cognitive radio system. The results demonstrated the effectiveness and the applicability of QGA in spectrum sharing in multi-user cognitive radio system.
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| 9. |
- Li, Fei, et al.
(författare)
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Improved quantum genetic algorithm for competitive spectrum sharing in cognitive radios
- 2012
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Ingår i: 2011 International Conference in Electrics, Communication and Automatic Control Proceedings. - New York, NY : Springer. - 9781441988485 - 9781441988492 ; , s. 1203-1209
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Konferensbidrag (refereegranskat)abstract
- This chapter investigates a kind of whole new approach to spectrum sharing in cognitive radio (CR) system, quantum-inspired approach. First, we improved Quantum Genetic Algorithm (QGA) by adding quantum crossover operator to overcome the shortcomings of the original QGA, easily falling into a local extremum when used to optimize the continuous functions with many extrema. We then propose a novel spectrum sharing scheme in noncooperative game for CR system based on our improved QGA. We use QGA as competitive strategies and provide simulation results that confirm the proposed schemes have better convergence rate and higher sum capacity than genetic algorithm (GA)-based scheme, namely at most 1 bit/s/Hz increase in capacity. The results demonstrate the effectiveness and the applicability of QGA in spectrum sharing in CR system.
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| 10. |
- Li, Fei, et al.
(författare)
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Innovation pedagogy and improving quality in higher education in web-based environments
- 2011
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Ingår i: 2011 IEEE 3rd International Conference on Communication Software and Networks. - : IEEE. - 9781612844855 - 9781612844862 ; , s. 215-218
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Konferensbidrag (refereegranskat)abstract
- Innovation is one of the main objectives for the higher education to meet the global challenges and to deliver the high levels of sustainable, knowledge-based growth. It is crucial to promote innovative pedagogy and improve quality. Based on the study of teaching programmes, pedagogies, web-based course management system and quality assurance system in engineering education at Umeå University, an innovative technology, Outcome-Based Approach, used in teaching at Umeå University is presented in this paper. The pedagogical experimentation taken by faculty teaching signal and system is described. Where the approach is successful is highlighted. The process of periodic review and revision of curricula is illustrated. The systematic quality work at Umeå University is described. Finally, some inspirations are drawn.
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