| 1. |
- Aad, G., et al.
(författare)
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- 2015
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Tidskriftsartikel (refereegranskat)
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| 2. |
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| 3. |
- Murmann, Patrick, et al.
(författare)
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Reconciling the What, When and How of Privacy Notifications in mHealth
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- The increasing number of mobile health (mhealth) devices deployed worldwide poses challenges to the privacy of their users, especially in terms of transparency. Privacy notifications constitute a conceptual means to facilitate transparency by providing users with situational awareness pertaining to the processing of their personal data. We present the results of two online surveys with cohorts consisting of English-speaking (n = 154) and German-speaking (n = 150) users of mhealth devices, conducted to elicit viable determinants of notification settings. We found quantitative evidence for the usefulness of privacy notifications, and for concordant predictors in terms of when and how users prefer to be notified about what kind of scenario. We conclude by providing tangible design guidelines for usable Transparency-Enhancing Tools (TETs) that harness privacy notifications to facilitate transparency, and that help users make informed decisions and take action in response.
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| 6. |
- Sayan, Ş., et al.
(författare)
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Hydrogenation of naphthalene and methylnaphthalene: modeling and spectroscopy
- 2002
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Ingår i: Journal of Molecular Catalysis A. - 1381-1169 .- 1873-314X. ; 185:1-2, s. 211-222
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Tidskriftsartikel (refereegranskat)abstract
- In situ infrared spectra of 1-methylnaphthalene (1-MeNapht) hydrogenation, over sulfided NiMo/Al2O3-TiO2 catalysts, were compared with theoretically derived properties of methylnaphthalene and its bicyclic products: MeDilin, MeTetralin, MeOctalin and MeDecalin, and with conversion data from literature. Comparisons were also made between the un-substituted and methyl-substituted two-rings, and between the 1- and 5-methyl isomers of 1,4-dihydronaphthalene (dilin) and 1,2,3,4-tetrahydronaphthalene (tetralin). IR spectra of MeNapht adsorption, on the sulfided catalyst, were matched with data for adsorption on the catalyst without sulfidation and the empty support. Surface bound MeNapht is observed below 250 °C on all catalysts. MeNapht adsorption suppresses OH groups non-discriminatory on the empty support and the metal loaded catalyst. We relate the results to previous data on the interaction between the supported metal sulfides and titanium modified aluminas. Calculated total energies, and experimentally derived heats of formation, pointed at decahydronaphthalene (decalin) as the dominant product of naphthalene hydrogenation, with tetralin as an abundant intermediate, and dilin and 1,2,3,4,5,6,7,8-octahydronaphthalene (octalin) as short lived transient stages. The spectroscopic modeling showed that the orbital fingerprints of the five bicyclic compounds were not distinctly different, nor more than marginally modified by methyl substitution or isomerization. The only significant difference came at the highest occupied orbital, where a high naphthalene density of states (DoS) overlapped with the valence bands of metal or metal sulfide catalysts. The vibrational bands for naphthalene, dilin, tetralin and octalin were well separated. Octalin and decalin, alone, have similar vibrational spectra. Upheaval of ring degeneracy for methyl-substituted two-ring structures broadened all infrared bands in a characteristic way.
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| 7. |
- Adamina, Michel, et al.
(författare)
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ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment
- 2024
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Ingår i: Journal of Crohn's & Colitis. - : OXFORD UNIV PRESS. - 1873-9946 .- 1876-4479.
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Tidskriftsartikel (refereegranskat)abstract
- This article is the second in a series of two publications on the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's disease. The first article covers medical management; the present article addresses surgical management, including preoperative aspects and drug management before surgery. It also provides technical advice for a variety of common clinical situations. Both articles together represent the evidence-based recommendations of the ECCO for Crohn's disease and an update of prior ECCO Guidelines.
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| 8. |
- Courseaux, A, et al.
(författare)
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Definition of the minimal MEN 1 candidate area based on a 5-Mb integrated map proximal to 11q13 : The european consortium on men1
- 1996
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Ingår i: Genomics. - : Elsevier BV. - 0888-7543 .- 1089-8646. ; 37:3, s. 345-353
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Tidskriftsartikel (refereegranskat)abstract
- Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder with a high penetrance characterized by tumors of the parathyroid glands, the endocrine pancreas, and the anterior pituitary. The MEN1 gene, a putative tumor suppressor gene, has been mapped to a 3- to 8-cM region in chromosome 11q13 but it remains elusive as yet. We have combined the efforts and resources from four laboratories to form the European Consortium on MEN1 with the aims of establishing the genetic and the physical maps of 11q13 and of further narrowing the MEN1 region. A 5-Mb integrated map of the region was established by fluorescence in situ hybridization on both metaphase chromosomes and DNA fibers, by hybridization to DNA from somatic cell hybrids containing various parts of human chromosome 11, by long-range restriction mapping, and by characterization of YACs and cosmids. Polymorphic markers were positioned and ordered by physical mapping and genetic linkage in 86 MEN1 families with 452 affected individuals. Two critical recombinants identified in two affected cases placed the MEN1 gene in an approximately 2-Mb region around PYGM, flanked by D11S1883 and D11S449.
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