| 1. |
- Garza, D, et al.
(författare)
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Use of a virtual human performance laboratory to improve integration of mathematics and biology in sports science curricula in Sweden and the United States.
- 2007
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Ingår i: Studies in Health Technology and Informatics.. ; 2007. Vol. 125, s. 140-142
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Tidskriftsartikel (refereegranskat)abstract
- New fields such as bioengineering are exploring the role of the physical sciences in traditional biological approaches to problems, with exciting results in device innovation, medicine, and research biology. The integration of mathematics, biomechanics, and material sciences into the undergraduate biology curriculum will better prepare students for these opportunities and enhance cooperation among faculty and students at the university level. We propose the study of sports science as the basis for introduction of this interdisciplinary program. This novel integrated approach will require a virtual human performance laboratory dual-hosted in Sweden and the United States. We have designed a course model that involves cooperative learning between students at Göteborg University and Stanford University, utilizes new technologies, encourages development of original research and will rely on frequent self-assessment and reflective learning. We will compare outcomes between this course and a more traditional didactic format as well as assess the effectiveness of multiple web-hosted virtual environments. We anticipate the grant will result in a network of original faculty and student research in exercise science and pedagogy as well as provide the opportunity for implementation of the model in more advance training levels and K-12 programs.
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| 2. |
- Garza, D, et al.
(författare)
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Use of a Virtual Human Performance Laboratory to Improve Integration of Mathematics and Biology in Sports Science Curricula in Sweden and the United States
- 2007
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Ingår i: Medicine Meets Virtual Reality 15 - in vivo, in vitro, in silico: Designing the Next in Medicine. Int. Conf., Long Beach Calif., US, 2007. - 9781586037130 ; 15
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- We are designing a course to be taught simultaneously at Göteborg University and Stanford University. We will present two approaches to creating a virtual environment in sport science experiments that are central to the course. The first virtual environment allows students at any location to utilize Marratech web-hosting software to conduct real-time experiments in venues as sophisticated as Lundberg Laboratories in Göteborg and the Stanford Human Performance Laboratory. We have conducted two trials to validate the feasibility of this design, which accommodates simple technologies such as a laptop and consumer devices at the participant site. The second virtual environment is a computer-generated biomechanics laboratory that will allow students to conduct experiments of their own design. Both Göteborg and Stanford will collect motion capture and force plate data on Olympic-caliber and professional athletes. Students will manipulate this data to conduct novel biomechanical investigations under the direction of a set of learning models under development.
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| 3. |
- Kölbel, Tilo, et al.
(författare)
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Extensive acute deep vein thrombosis of the iliocaval segment: midterm results of thrombolysis and stent placement.
- 2007
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Ingår i: Journal of Vascular and Interventional Radiology. - : Elsevier BV. - 1051-0443. ; 18:2, s. 243-250
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To evaluate patency and clinical outcome in patients treated with catheter-directed thrombolysis and stent placement for acute extensive thrombosis affecting the iliocaval segment. MATERIALS AND METHODS: During a 10-year period (1994-2005), 37 patients with 44 limbs (26 female, median age 31 years) with acute extensive venous thrombosis affecting the iliocaval segment were treated with catheter-directed thrombolysis. Angioplasty and stent placement was performed in 36 limbs (82%) for underlying stenosis or residual thrombosis. A prospectively registered database was analyzed in combination with a telephone interview about clinical symptoms. RESULTS: Technical success was achieved in all 44 limbs and clinical success in 42 of 44 (96%) limbs. Primary patency after a median imaging follow-up interval of 16 months was 34 of 44 (77%) limbs, assisted primary patency was 38 of 44 (86%) limbs, and secondary patency was 39 of 44 (89%) limbs. Thirty of 44 (68%) limbs were asymptomatic after a median clinical follow-up of 27 months, eight (18%) limbs were moderately improved, two (5%) limbs were unchanged, two (5%) limbs were moderately worse, and two (5%) limbs had no clinical follow-up. Complications occurred in six (16%) patients, three (8%) of which were major complications. No patient developed symptomatic pulmonary embolism. CONCLUSIONS: Catheter-directed thrombolysis and stent placement is a safe and effective treatment for acute iliocaval thrombosis. Clinical midterm results are encouraging. Thrombolyzed and stented segments remain patent in the vast majority of patients after 16 months. Primary and aggressive stent placement in the iliocaval vein segments can prevent rethrombosis and ensure patency.
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| 4. |
- Lindh, Jacob, 1971, et al.
(författare)
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Blended learning through global network and interdisciplinary live distance experiments at human performance laboratories.
- 2009
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Ingår i: Learning in the Synergy of Multiple Disciplines, 4th European Conference on Technology Enhanced Learning, EC-TEL 2009, Nice, France, September 29 - October 2, 2009.. - : Springer. - 9783642046353 ; 5794 Springer 2009
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Tidskriftsartikel (refereegranskat)abstract
- Under a previous grant (2005-2008) we designed an interdisciplinary inquiry-based laboratory course in sports kinesiology, taught simultaneously over the Internet for undergraduate students at the University of Gothenburg and at Stanford University. Student groups developed their own research questions, conducted online distance experiments, processed their unique data with support from an interdisciplinary global network of expert consultants, and presented original scientific results. We will demonstrate one virtual experiment that is central to the course to conference attendees and present a unique set of interactive learning tools for the scientific process. This student-conducted experiment was first tested in a laboratory in Stockholm in 2007, and broadcasted live to three universities, with experts and students actively taking part via Polycom and Marratech. Real-time communication was possible in all directions through a moderator in Stockholm. Our course model seems to improve student learning outcomes while advancing the field of sports science.
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| 5. |
- Lindh, Jonas, et al.
(författare)
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Cryptogenic polyneuropathy : Clinical and neurophysiological findings
- 2005
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Ingår i: Journal of the peripheral nervous system. - : Wiley. - 1085-9489 .- 1529-8027. ; 10:1, s. 31-37
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of this study was to describe the clinical and neurophysiological features of cryptogenic polyneuropathy in 168 patients in the neurological departments at three Swedish hospitals. The medical records of all patients aged 40-79 years with the diagnosis of cryptogenic polyneuropathy from 1993 to 2000 were analysed. One hundred and fourteen patients (68%) were men. The mean age at first symptom was 61 years and at diagnosis it was 64 years. Distal numbness (n=115, 68%) was the most common symptom, but some patients complained of pain, pedal paresthesiae, and impairment of balance. The most common clinical findings were decreased or lost proprioception or sense of vibration (n=135, 80%) and loss of ankle jerks (n=131, 78%). Neurography in 139 patients showed mixed sensorimotor polyneuropathy of axonal or mixed axonal and demyelinating type in 97 (70%). Cryptogenic polyneuropathy is a slowly progressive sensorimotor nerve lesion of mainly axonal type. Men are more often affected than women. Most patients have a minor or moderate severe polyneuropathy.
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| 6. |
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| 7. |
- Lindh, Magnus, 1960, et al.
(författare)
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Monitoring treatment response by the hepatitis C virus core antigen assay.
- 2005
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Ingår i: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. - : Springer Science and Business Media LLC. - 0934-9723. ; 24:3, s. 230-2
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Forskningsöversikt (refereegranskat)
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| 8. |
- Lindh, Magnus, 1960, et al.
(författare)
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Response prediction and treatment tailoring for chronic hepatitis C virus genotype 1 infection
- 2007
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Ingår i: J Clin Microbiol. - 0095-1137. ; 45:8, s. 2439-45
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Tidskriftsartikel (refereegranskat)abstract
- We monitored early viral response during the treatment of hepatitis C virus (HCV) infection with the aim of identifying predictors of treatment outcome. We studied 53 patients with genotype 1 infection who received 180 microg/week pegylated interferon alfa-2a and 1,000 or 1,200 mg/day ribavirin depending on body weight and serially assessed HCV RNA in serum, using the Cobas TaqMan assay. Thirty-one patients (58%) achieved sustained viral response (SVR). SVR was obtained in 100% (10/10) of patients with pretreatment viremia concentrations below 400,000 IU/ml, in 100% (14/14) of patients with more than 1.5 log reduction of HCV RNA after 4 days of treatment, and in 95% (22/23) of patients with a rate of decline in viremia higher than 0.70 log units/week during the second phase. Non-SVR was seen in all patients with a second-phase decline rate lower than 0.35 log units/week. Patients with slopes between 0.50 and 0.80 log units/week achieved SVR (4/4) unless the treatment dose was modified (3/3). We conclude that the second-phase slope appears to be an accurate and useful predictor of treatment response. On the basis of these findings, we propose a model of tailored treatment which takes into account the second-phase slope and the amount of HCV RNA after 21 days of treatment.
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| 9. |
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| 10. |
- Svensk, Ann-Christine, et al.
(författare)
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Art therapy improves experienced quality of life among women undergoing treatment for breast cancer : A randomized controlled study
- 2009
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Ingår i: European Journal of Cancer Care. - : John Wiley & Sons Inc.. - 0961-5423 .- 1365-2354. ; 18:1, s. 69-77
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Tidskriftsartikel (refereegranskat)abstract
- Women with breast cancer are naturally exposed to strain related to diagnosis and treatment, and this influences their experienced quality of life (QoL). The present paper reports the effect, with regard to QoL aspects, of an art therapy intervention among 41 women undergoing radiotherapy treatment for breast cancer. The women were randomized to an intervention group with individual art therapy sessions for 1 h/week (n = 20), or to a control group (n = 21). The WHOQOL-BREF and EORTC Quality of Life Questionnaire-BR23, were used for QoL assessment, and administrated on three measurement occasions, before the start of radiotherapy and 2 and 6 months later. The results indicate an overall improvement in QoL aspects among women in the intervention group. A significant increase in total health, total QoL, physical health and psychological health was observed in the art therapy group. A significant positive difference within the art therapy group was also seen, concerning future perspectives, body image and systemic therapy side effects. The present study provides strong support for the use of art therapy to improve QoL for women undergoing radiotherapy treatment for breast cancer.
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