| 1. |
- Araújo, Mauricio G, et al.
(författare)
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Modeling of the buccal and lingual bone walls of fresh extraction sites following implant installation.
- 2006
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Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 17:6, s. 606-14
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To determine whether the reduction of the alveolar ridge that occurs following tooth extraction and implant placement is influenced by the size of the hard tissue walls of the socket. MATERIAL AND METHODS: Six beagle dogs were used. The third premolar and first molar in both quadrants of the mandible were used. Mucoperiostal flaps were elevated and the distal roots were removed. Implants were installed in the fresh extraction socket in one side of the mandible. The flaps were replaced to allow a semi-submerged healing. The procedure was repeated in the contra later side of the mandible after 2 months. The animals were sacrificed 1 month after the final implant installation. The mandibles were dissected, and each implant site was removed and processed for ground sectioning. RESULTS: Marked hard tissue alterations occurred during healing following tooth extraction and implant installation in the socket. The marginal gap that was present between the implant and the walls of the socket at implantation disappeared as a result of bone fill and resorption of the bone crest. The modeling in the marginal defect region was accompanied by marked attenuation of the dimensions of both the delicate buccal and the wider lingual bone wall. Bone loss at molar sites was more pronounced than at the premolar locations. CONCLUSION: Implant placement failed to preserve the hard tissue dimension of the ridge following tooth extraction. The buccal as well as the lingual bone walls were resorbed. At the buccal aspect, this resulted in some marginal loss of osseointegration.
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| 2. |
- Araújo, Mauricio G, 1966, et al.
(författare)
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Ridge alterations following implant placement in fresh extraction sockets: an experimental study in the dog.
- 2005
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Ingår i: Journal of clinical periodontology. - 0303-6979. ; 32:6, s. 645-52
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To study dimensional alterations of the alveolar ridge that occurred following implant placement in fresh extraction sockets. MATERIAL AND METHODS: Five beagle dogs were included in the study. In both quadrants of the mandible, incisions were made in the crevice region of the third and fourth pre-molars. Buccal and minute lingual full-thickness flaps were elevated. The mesial root of the four pre-molars root was filled and the teeth were hemi-sected. Following flap elevation in (3)P(3) and (4)P(4) regions, the distal roots were removed. In the right jaw quadrants, implants with a sand blasted and acid etched (SLA) surface were placed in the fresh extraction sockets, while in the left jaws the corresponding sockets were left for spontaneous healing. The mesial roots were retained as surgical control teeth. After 3 months, the animals were examined clinically, sacrificed and tissue blocks containing the implant sites, the adjacent tooth sites (mesial root) and the edentulous socket sites were dissected, prepared for ground sectioning and examined in the microscope. RESULTS: At implant sites, the level of bone-to-implant contact (BC) was located 2.6+/-0.4 mm (buccal aspect) and 0.2+/-0.5 mm (lingual aspect) apical of the SLA level. At the edentulous sites, the mean vertical distance (V) between the marginal termination of the buccal and lingual bone walls was 2.2+/-0.9 mm. At the surgically treated tooth sites, the mean amount of attachment loss was 0.5+/-0.5 mm (buccal) and 0.2+/-0.3 mm (lingual). CONCLUSIONS: Marked dimensional alterations had occurred in the edentulous ridge after 3 months of healing following the extraction of the distal root of mandibular pre-molars. The placement of an implant in the fresh extraction site obviously failed to prevent the re-modelling that occurred in the walls of the socket. The resulting height of the buccal and lingual walls at 3 months was similar at implants and edentulous sites and vertical bone loss was more pronounced at the buccal than at the lingual aspect of the ridge. It is suggested that the resorption of the socket walls that occurs following tooth removal must be considered in conjunction with implant placement in fresh extraction sockets.
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| 3. |
- Araújo, Mauricio G, 1966, et al.
(författare)
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The influence of Bio-Oss collagen on healing of an extraction socket: An experimental study in the dog.
- 2008
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Ingår i: The International Journal of Periodontics & Restorative Dentistry. - 0198-7569. ; 28:2, s. 123-135
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Tidskriftsartikel (refereegranskat)abstract
- Background: Different approaches were advocated to preserve or improve the dimension and contour of the ridge following tooth extraction. In some of studies socket grafting apparently had a successful outcome while in other reports the benefits of such therapy were more questionable. Aim: The objective of the present experiment was to evaluate the effect on hard tissue modeling and remodeling of the placement of a xenograft in the fresh extraction socket in dogs. Material and Methods: Five mongrel dogs were used. Two mandibular premolars (4P4) were hemi-sected. The distal roots were carefully removed. In one socket, a graft consisting of Bio-Oss® Collage was placed while the contra-lateral site was left without grafting. After 3 months of healing, the dogs were euthanized and biopsies sampled. From each experimental site, 4 ground sections – 2 from the mesial root and 2 from the healed socket – were prepared, stained and examined in the microscope. Results: The placement of Bio-Oss® Collagen in the fresh extraction socket failed to inhibit the processes of modeling and remodeling that took place in the socket walls following tooth extraction. The biomaterial, however, apparently promoted de novo hard tissue formation, in particular in the cortical region of the extraction site. Hereby, the dimension of the hard tissue was maintained and the profile of the ridge was better preserved. Conclusion: The placement of a biomaterial in an extraction socket may promote bone modeling and at least temporarily compensate for marginal ridge contraction.
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| 4. |
- Araújo, Mauricio G, et al.
(författare)
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Tissue modeling following implant placement in fresh extraction sockets.
- 2006
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Ingår i: Clinical oral implants research. - : Wiley. - 0905-7161 .- 1600-0501. ; 17:6, s. 615-24
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To study whether osseointegration once established following implant placement in a fresh extraction socket may be lost as a result of tissue modeling. MATERIAL AND METHODS: Seven beagle dogs were used. The third and fourth premolars in both quadrants of the mandible were used as experimental teeth. Buccal and lingual full-thickness flaps were elevated and distal roots were removed. Implants were installed in the fresh extraction socket. Semi-submerged healing of the implant sites was allowed. In five dogs, the experimental procedure was first performed in the right side of the mandible and 2 months later in the left mandible. These five animals were sacrificed 1 month after the final implant installation. In two dogs, the premolar sites on both sides of the mandible were treated in one surgical session and biopsies were obtained immediately after implant placement. All biopsies were processed for ground sectioning and stained. RESULTS: The void that existed between the implant and the socket walls at surgery was filled at 4 weeks with woven bone that made contact with the SLA surface. In this interval, (i) the buccal and lingual bone walls underwent marked surface resorption and (ii) the height of the thin buccal hard tissue wall was reduced. The process of healing continued, and the buccal bone crest shifted further in the apical direction. After 12 weeks, the buccal crest was located>2 mm apical of the marginal border of the SLA surface. CONCLUSION: The bone-to-implant contact that was established during the early phase of socket healing following implant installation was in part lost when the buccal bone wall underwent continued resorption.
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| 5. |
- Bogren, Anna, 1963, et al.
(författare)
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A three-year prospective study of adult subjects with gingivitis. I: clinical periodontal parameters.
- 2007
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Ingår i: Journal of clinical periodontology. - 0303-6979. ; 34:1, s. 1-6
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Tidskriftsartikel (refereegranskat)abstract
- AIM: The objective of this study was to monitor prospectively clinical parameters in subjects without signs of destructive periodontal disease who were involved in a primary prevention programme, and to determine the changes that occurred between yearly examinations over a 3-year period. MATERIAL AND METHODS: One hundred and twenty-six subjects aged at least 20 years with a maximum of two tooth sites with probing pocket depth (PPD)>4 mm and no proximal sites with clinical attachment loss participated in the study. Primary prevention was provided at baseline of the study and then every 6 months. Plaque, bleeding on probing (BoP) and PPD were scored at baseline, 1, 2 and 3 years. RESULTS: There were no significant changes in the plaque score over the 3 years. After year 1, the BoP score was significantly improved with 5.6%, while no further improvement in BoP was found at years 2 and 3. The mean PPD decreased from 2.3 to 2.1 mm over the 3 years (p<0.05). CONCLUSION: Although some individuals exhibiting minor signs of periodontal pathology may have benefited from the primary prevention, the overall clinical improvement was limited for such subjects in the present 3-year study.
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| 6. |
- Lindhe, Jan, 1935, et al.
(författare)
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The Mucosa at Teeth and Implants
- 2008
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Ingår i: Clinical Periodontology and Implant Dentistry. - Oxford : Blackwell Munksgaard. - 9781405160995 ; , s. 69-85
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 7. |
- Wennström, Jan, 1947, et al.
(författare)
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Implant-supported single-tooth restorations: a 5-year prospective study.
- 2005
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Ingår i: Journal of clinical periodontology. - 0303-6979. ; 32:6, s. 567-74
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Comparatively few studies are available reporting at least 5 years of follow-up data of implant-supported single-tooth replacements. OBJECTIVE: To evaluate prospectively the 5-year outcome of implant-supported single-tooth prosthetic restorations. MATERIAL AND METHODS: Forty subjects (mean age 41 years), 23 males and 17 females, who required single-tooth prosthetic replacement for a missing tooth were recruited. A total of 45 self-tapping implants (Astra Tech ST-implants)--40 in the maxilla and five in the mandible--were installed in a two-stage procedure. Abutment connection was performed 3-6 months after implant installation. Clinical and radiographic examinations were performed at the completion of the prosthetic treatment and once a year during a 5-year follow-up period. The analysis of peri-implant bone level alteration was performed on subject and implant levels and by the use of analysis of variance and binary logistic regression. RESULTS: Three patients were lost during the 5 years of follow-up. One implant was lost after 2.5 years in function and another four implants could not be accounted for at the 5-year follow-up examination. The overall failure rate at 5 years was 2.6% (subject level) and 2.3% (implant level). The mean loss of marginal bone at the implants during the first year in function was 0.06 mm (SD 0.67) on the subject level and 0.02 mm (0.65) on the implant level. During the subsequent 4 years the annual change in peri-implant bone level amounted to -0.02 mm (0.22) on both subject and implant levels. Thus, the mean total bone level change over the 5-year interval was -0.14 mm (1.04) on subject level and -0.11 mm (1.00) on the implant level of analysis (p>0.05). The frequency of implants with a 5-year bone loss of > or =1 mm was 13%. Approximately 50% of the implants demonstrated no bone loss. CONCLUSION: The present clinical trial on single-tooth replacements with the Astra Tech implant system demonstrated that the bone loss during the first year of function as well as annually thereafter was small.
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| 8. |
- Wennström, Jan, 1947, et al.
(författare)
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Periodontal Surgery: Access Therapy
- 2008
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Ingår i: Clinical Periodontology and Implant Dentistry. - Oxford : Blackwell Munksgaard. - 9781405160995 ; , s. 783-822
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 9. |
- Araújo, M, et al.
(författare)
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Effect of a xenograft on early bone formation in extraction sockets: an experimental study in dog.
- 2009
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Ingår i: Clinical oral implants research. - : Wiley. - 1600-0501 .- 0905-7161. ; 20:1, s. 1-6
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Tidskriftsartikel (refereegranskat)abstract
- AIM: The aim of this study was to study the effect on early bone formation resulting from the placement of a xenograft in the fresh extraction socket in dogs. MATERIAL AND METHODS: Five beagle dogs were used. The distal roots of the third and fourth mandibular premolars were removed. In one quadrant, a graft consisting of Bio-Oss Collagen was placed in the fresh extraction wound, while the corresponding premolar sites in the contra-lateral jaw quadrant were left non-grafted. After 2 weeks of healing, the dogs were perfused with a fixative, the mandibles removed, the experimental sites dissected, demineralized, sectioned in the mesio-distal plane and stained in hematoxyline-eosine. RESULTS: The central portion of the non-grafted sockets was occupied by a provisional matrix comprised of densely packed connective tissue fibers and mesenchymal cells. Apical and lateral to the provisional matrix, newly formed woven bone was found to occupy most of the sockets. In the apical part of the grafted sockets, no particles of the xenograft could be observed but newly formed bone was present in this portion of the experimental site. In addition, limited numbers of woven bone trabeculae occurred along the lateral socket walls. The central and marginal segments of the grafted sockets, however, were occupied by a non-mineralized connective tissue that enclosed Bio-Oss particles that frequently were coated by multinucleated cells. CONCLUSIONS: The placement of Bio-Oss Collagen in the fresh extraction wound obviously delayed socket healing. Thus, after 2 weeks of tissue repair, only minute amounts of newly formed bone occurred in the apical and lateral borders of the grafted sockets, while large amounts of woven bone had formed in most parts of the non-grafted sites.
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| 10. |
- Araújo, Mauricio G, 1966, et al.
(författare)
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Dimensional ridge alterations following tooth extraction. An experimental study in the dog.
- 2005
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Ingår i: Journal of clinical periodontology. - 0303-6979. ; 32:2, s. 212-8
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To study dimensional alterations of the alveolar ridge that occurred following tooth extraction as well as processes of bone modelling and remodelling associated with such change. MATERIAL AND METHODS: Twelve mongrel dogs were included in the study. In both quadrants of the mandible incisions were made in the crevice region of the 3rd and 4th premolars. Minute buccal and lingual full thickness flaps were elevated. The four premolars were hemi-sected. The distal roots were removed. The extraction sites were covered with the mobilized gingival tissue. The extractions of the roots and the sacrifice of the dogs were staggered in such a manner that all dogs contributed with sockets representing 1, 2, 4 and 8 weeks of healing. The animals were sacrificed and tissue blocks containing the extraction socket were dissected, decalcified in EDTA, embedded in paraffin and cut in the buccal-lingual plane. The sections were stained in haematoxyline-eosine and examined in the microscope. RESULTS: It was demonstrated that marked dimensional alterations occurred during the first 8 weeks following the extraction of mandibular premolars. Thus, in this interval there was a marked osteoclastic activity resulting in resorption of the crestal region of both the buccal and the lingual bone wall. The reduction of the height of the walls was more pronounced at the buccal than at the lingual aspect of the extraction socket. The height reduction was accompanied by a "horizontal" bone loss that was caused by osteoclasts present in lacunae on the surface of both the buccal and the lingual bone wall. CONCLUSIONS: The resorption of the buccal/lingual walls of the extraction site occurred in two overlapping phases. During phase 1, the bundle bone was resorbed and replaced with woven bone. Since the crest of the buccal bone wall was comprised solely of bundle this modelling resulted in substantial vertical reduction of the buccal crest. Phase 2 included resorption that occurred from the outer surfaces of both bone walls. The reason for this additional bone loss is presently not understood.
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