| 1. |
- Bejerholm, Ulrika, et al.
(författare)
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Rasch Analysis of the Profiles of Occupational Engagement in people with Severe mental illness (POES) instrument
- 2015
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Ingår i: Health and Quality of Life Outcomes. - : Springer Science and Business Media LLC. - 1477-7525. ; 13
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Tidskriftsartikel (refereegranskat)abstract
- Purpose: The Profiles of Occupational Engagement in people with Severe mental illness (POES) instrument was developed to study time use profiles of occupations and measure the extent they are characterized by engagement. However, the dimensional factors are not known. The aim of the present study was to establish the internal construct validity of the POES using the Rasch measurement model. Methods: A sample of 192 outpatients in Sweden was administered the POES and data were subjected to Rasch analysis. Results: The POES showed good fit to the Rasch model after accommodation for local dependency. The nine items had high reliability as measured by person separation index, and no threshold disordering was present. Differential item functioning analysis showed no significant differences across groups of age, sex, diagnosis, or country of origin. Conclusion: The POES is a unidimensional scale that represents a continuum of occupational engagement. The transformed POES sum score can be used on an interval scale to measure status and changes in occupational engagement in mental health practice and research.
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| 2. |
- Bärring, Maja, 1988, et al.
(författare)
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5G Enabled Manufacturing Evaluation for Data-Driven Decision-Making
- 2018
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Ingår i: Procedia CIRP. - : Elsevier BV. - 2212-8271. ; 27, s. 266-271
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Konferensbidrag (refereegranskat)abstract
- Manufacturing industries are experiencing a technical paradigm shift that will change how they run their operations. Equipment and personnel generate an ever-increasing amount of data, and connectivity enables to utilize data to a larger extent. Connecting a machine is not a technical obstacle anymore, but with all available data, the challenge is to understand the requirements of data to support efficient decision-making. This paper will address the requirements of data by domain experts, in the context of more real-time data available. A focus group interview was performed, assessing the key factors of big data; volume, velocity, and variety of data.
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| 3. |
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| 4. |
- Llona-Minguez, Sabin, et al.
(författare)
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Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1
- 2017
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Ingår i: Journal of Medicinal Chemistry. - : American Chemical Society (ACS). - 0022-2623 .- 1520-4804. ; 60:5, s. 2148-2154
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Tidskriftsartikel (refereegranskat)abstract
- The dCTP pyrophosphatase 1 (dCTPase) is involved in the regulation of the cellular dNTP pool and has been linked to cancer progression. Here we report on the discovery of a series of 3,6-disubstituted triazolothiadiazoles as potent dCTPase inhibitors. Compounds 16 and 18 display good correlation between enzymatic inhibition and target engagement, together with efficacy in a cellular synergy model, deeming them as a promising starting point for hit -to-lead development.
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| 5. |
- Lundgren, Camilla, 1989, et al.
(författare)
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Challenges Building a Data Value Chain to Enable Data-Driven Decisions: A Predictive Maintenance Case in 5G-Enabled Manufacturing
- 2018
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Ingår i: Procedia Manufacturing. - : Elsevier BV. - 2351-9789. ; 17, s. 411-418
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Konferensbidrag (refereegranskat)abstract
- Improvements in data storage and processing technologies have led many managers to change how they make decisions, relying less on intuition and more on data. This trend is especially notable for the manufacturing industry where Big Data applications, i.e. data analytics, are mentioned as an important enabler of value creation with the event of the fourth industrial revolution. Designing and building the entire data value chain that enables Big Data applications in manufacturing requires new knowledge about digital technologies combined with already established knowledge about the specific manufacturing processes. This paper focuses on the convergence of these different knowledge spaces applied to a specific case of implementing a Big Data application for predictive maintenance. Every step of building the data value chain from data acquisition to system feedback is presented and discussed in terms of the major challenges that were observed during the project. Results show that, just as the literature suggests, the knowledge gaps between different domains is a key component to manage for succeeding when building Big Data applications in the context of future manufacturing and maintenance.
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| 6. |
- Lundgren, Dan
(författare)
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Leadership, psychosocial work environment, and satisfaction with elder care among care recipients : Analysing their associations and the structural differences between nursing homes and home care
- 2018
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- BackgroundMunicipal elder care has become increasingly multifaceted, and the quest for quality is a continuing discussion in Swedish elder care. In recent decades, municipalities have prioritized older adults with severe needs. There is also a trend of more elderly individuals receiving care in their own homes. The number of persons 80 years and older will increase by approximately 75 percent between 2015 and 2035. During the same period, the numbers of nursing assistants are likely to decrease. Furthermore, health and social care services have the highest rates of sick leave in Sweden, and the psychosocial work environment plays an important role in reducing sick leave. Perceived support from an organization, leaders and colleagues has been shown to have a positive effect on nursing assistants’ perceptions of the psychosocial work environment in elder care settings. Leadership characteristics or attributes and behaviours have been associated with a healthy work environment. Thus, knowledge regarding the associations between leadership, the psychosocial work environment, and recipient satisfaction in elder care is insufficient.AimsThe overall aim of this thesis was to explore and describe the associations between leadership, the psychosocial work environment, and recipient satisfaction in municipal elder care, the changes over time in psychosocial work environment, and the difference between nursing homes and home care.Design and methodsThis thesis is based on four cross-sectional studies (I-IV) and one study based on repeated cross-sectional analyses (V). Data from three different surveys were used: the Developmental Leadership Questionnaire (DLQ), the Questionnaire for Psychological and Social Factors at Work (QPS), and a recipient satisfaction survey (based on a National Board of Health and Welfare recipient satisfaction survey). Study I analyses first-line managers’ assessments of their leadership and nursing assistants’ assessments of their first-line managers. Study II analyses the associations between leadership and the psychosocial work environment, study III the associations between psychosocial work environment and recipient satisfaction, and study IV encompasses all three levels, leadership and the psychosocial work environment, and recipient satisfaction. Study V describes changes in the psychosocial work environment between 2007 and 2015.Results There are structural differences between nursing homes and home care in the assessments of leadership, the psychosocial work environment, and satisfaction among older people. Linear trends for the period 2007-2015 demonstrate a decline in control at work in both nursing homes and home care and positive trends for stimulus from the work itself. The results also show that nursing assistants in nursing homes rate their psychosocial work environment higher than nursing assistants in home care. Older adults receiving home care report higher satisfaction than those receiving care in nursing homes. In contrast, nursing assistants in home care rate their first-line managers’ leadership and their perceived psychosocial work environment lower than those working in nursing homes. Process-related factors, for example, the association between leadership and the psychosocial work environment, showed that interpersonal factors, such as support from superiors, empowering leadership, human resource primacy, and direct leadership, may impact nursing assistants’ psychosocial work environment in both nursing homes and home care. A better psychosocial work environment among nursing assistants was associated with higher satisfaction among recipients of elder care, except for the recipient satisfaction item staff knowledge, which had negative associations with the psychosocial work environment.Conclusions and implications for practiceTo influence nursing assistants’ performance, to increase recipient satisfaction and to increase quality in eldercare in the long term, appropriate leadership and a healthy psychosocial work environment are necessary. To make the most out of the available resources and to meet future challenges (among others) in elder care require organizational attention so that leadership and psychosocial work environments continue to develop in both nursing homes and home care. Therefore, structural differences in elder care must be considered to create a better psychosocial work environment for nursing assistants and, in turn, to create higher care satisfaction for those who are receiving elder care in two different social contexts.
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| 7. |
- Lundgren, Dan, et al.
(författare)
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The Impact of Leadership and Psychosocial Work Environment on Recipient Satisfaction in Nursing Homes and Home Care
- 2019
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Ingår i: Gerontology and geriatric medicine. - : SAGE Publications. - 2333-7214. ; 5, s. 1-9
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Tidskriftsartikel (refereegranskat)abstract
- This study examines the association between nursing assistants' assessment of leadership, their psychosocial work environment, and satisfaction among older people receiving care in nursing homes and home care. Cross-sectional surveys were conducted with nursing assistants (n = 1,132) and people receiving care (n = 1,535) in 45 nursing homes and 21 home care units. Direct leadership was associated with the psychosocial work environment in nursing homes and home care. Furthermore, better leadership was related to higher satisfaction among nursing assistants and older people in nursing homes. Thus, indirect leadership had no effect on recipients' satisfaction in either nursing homes or home care. The path analysis showed an indirect effect between leadership factors and recipient satisfaction. The findings suggest that the psychosocial work environment of nursing assistants and recipient satisfaction in nursing homes can be increased by improving leadership.
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| 8. |
- Nettelbladt, Ulrika, et al.
(författare)
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Barn med språkliga svårigheter
- 2017. - 1
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Ingår i: Barnneurologi. - 9789144078885 ; , s. 615-617
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Bokkapitel (refereegranskat)
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| 9. |
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| 10. |
- Åkerman, Magnus, 1978, et al.
(författare)
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Technical Interoperability for Machine Connectivity on the Shop Floor
- 2018
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Ingår i: Technologies. - : MDPI AG. - 2227-7080. ; 6:3
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents a generic technical solution that can increase Industry 4.0 maturity by collecting data from sensors and control systems on the shop floor. Within the research project “5G-Enabled Manufacturing”, an LTE (Long-Term Evolution) network with 5G technologies was deployed on the shop floor to enable fast and scalable connectivity. This network was used to connect a grinding machine to a remote private cloud where data was stored and streamed to a data analytics center. This enabled visibility and transparency of the production data, which is the basis for Industry 4.0 and smart manufacturing. The solution is described with a focus on high-level communication technologies above wireless communication standards. These technologies are discussed regarding technical interoperability, focusing on the system layout, communication standards, and open systems. From the discussion, it can be derived that generic solutions such as this are possible, but manufacturing end-users must expand and further internalize knowledge of future information and communication technologies to reduce their dependency on equipment and technology providers.
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