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- Baranzahi, Amir, et al.
(author)
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Response of metal-oxide-silicon carbide sensors to simulated and real exhaust gases
- 1997
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In: Sensors and actuators. B, Chemical. - : Elsevier. - 0925-4005 .- 1873-3077. ; 43:1-3, s. 52-59
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Journal article (peer-reviewed)abstract
- Field effect devices based on catalytic metal-oxide-silicon carbide (MOSiC) structures can be used as high temperature gas sensors. The devices are sensitive to hydrocarbons and hydrogen and can be operated up to at least 900 degrees C, which make them suitable for several combustion applications, Simulated and real exhaust gases from a car engine have been studied at sensor temperatures from 200 to 650 degrees C, and it was round that the sensor signal is high for excess hydrocarbon and low for excess oxygen. The response time is less than 100 ms and only a small degradation of the devices was observed after several days of operation. The devices also react to changes of the gas composition In the fuel-rich and fuel-lean region. The devices show an interesting temperature dependence in the fuel rich region.
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| 5. |
- Hansson, Kenny, 1972-, et al.
(author)
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Surface plasmon resonance (SPR) analysis of coagulation in whole blood with application in prothrombin time assay
- 1999
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In: Biosensors & bioelectronics. - 0956-5663 .- 1873-4235. ; 14:8-9, s. 671-682
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Journal article (peer-reviewed)abstract
- It is previously shown that surface plasmon resonance (SPR) can be used to study blood plasma coagulation. This work explores the use of this technique for the analysis of tissue factor induced coagulation, i.e. prothrombin time (PT) analysis, of whole blood and plasma. The reference method was nephelometry. The prothrombin time analysis by SPR was performed by mixing two volumes of blood/plasma, one volume of thromboplastin, and one volume of CaCl2 solution directly on a sensor surface. The measurements show good agreement between nephelometry and SPR plasma analysis and also between SPR plasma and whole blood analysis. The effect of anticoagulant treatment on the clotting times was significant both quantitatively and qualitatively. The impact on the SPR signal of different physiological events in the coagulation process is discussed, and tentative interpretations of the sensorgram features are given. The major advantage of the SPR method compared to nephelometry is the possibility to perform analysis on whole blood instead of plasma. In conclusion, SPR is a promising method for whole blood coagulation analysis.
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| 6. |
- Holmqvist, P, et al.
(author)
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Apoptosis and Bcl-2 expression in relation to age, tumor characteristics and prognosis in breast cancer
- 1999
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In: International Journal of Biological Markers. - 0393-6155 .- 1724-6008. ; 14:2, s. 84-91
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Journal article (peer-reviewed)abstract
- The extent of apoptosis and the expression of Bcl-2 was investigated in tumor samples from 165 women who underwent surgery for primary breast carcinoma between 1989 and 1990 in South-East Sweden. Apoptosis was assessed by a DNA fragmentation assay for flow cytometry. Bcl-2 protein expression was analyzed with immunocytochemistry. Bcl-2 immunoreactivity correlated with estrogen receptor (ER) and progesterone receptor (PgR) positivity and was inversely correlated with p53 accumulation. Apoptosis increased with patient age and a high degree of apoptosis was negatively associated with Bcl-2 immunostaining. Apoptosis showed no significant correlation with any of the other variables studied, including prognosis. The group with Bcl-2-positive tumors tended to have a lower risk of distant recurrence than others, but the association of Bcl-2 with recurrence was different in groups divided by ER and PgR status. Whereas Bcl-2 positivity indicated a low recurrence rate among PgR-negative patients, in the PgR-positive group, those with Bcl-2-positive tumors showed a non significantly higher recurrence rate than Bcl-2-negative cases. In the PgR-positive group, Bcl-2-positive tumors also appeared more frequently to be lymph node positive and DNA aneuploid. The results suggest that hormone receptor status is of importance for the prognostic role of Bcl-2. Likewise, patient age merits consideration when apoptosis is studied in human cancer.
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| 7. |
- Karlsteen, M., et al.
(author)
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Electrical properties of inhomogeneous SiC MIS structures
- 1995
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In: Journal of Electronic Materials. - : Springer. - 0361-5235 .- 1543-186X. ; 24:7, s. 853-861
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Journal article (peer-reviewed)abstract
- Current-voltage characteristics of metal contacts on 6H-SiC with a thin (5-20 Angstrom) oxide layer have been measured in the temperature range 300 to 1000K. The contacts were investigated in both H-2 and O-2-atmospheres. As the SiC surface was nonideal due to pin holes and other defects generated during the growth process, it was necessary to treat the Schottky contacts as inhomogeneous contacts. The inhomogeneity explains the nonideal current-voltage behavior of the contacts such as ideality factors much larger than unity and voltage dependent ideality factors. It was found that some metals gave Schottky contacts in the entire temperature range, while other metals were ohmic at higher temperatures. Several different contact metals were investigated: Al, Ti, TaSix, and Pd were found to be ohmic at high temperatures, while Pt, Pt+Cr, Ni, Cr and another TaSix contact were found to behave like Schottky contacts in the entire temperature range. This is a preliminary investigation of the electrical characteristics of different metals that could be useful for high temperature gas sensor purposes.
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