| 1. |
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
- Magnusson, M, et al.
(författare)
-
Reduction of the time constant in the VOR as a protective mechanism in acute vestibular lesions
- 1989
-
Ingår i: Acta Oto-Laryngologica, Supplement. - 0365-5237. ; 468, s. 32-329
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Fourteen patients with vestibular neuritis were examined at onset of symptoms and after one year. Postrotatory time constant and gain in the vestibulo-ocular reflex (VOR) were measured after rotation with a velocity step of 150 deg/s. There was no significant difference in gain towards the healthy side at onset of the disease compared to recordings after one year. The time constant towards the healthy side was significantly shorter at onset compared to measurements after one year. The results reflect the loss of unilateral vestibular function on the velocity storage mechanism, both in the acute situation and after compensation. The findings indicate that reduction of the time constant in the VOR is not only due to unilaterally vestibular impairment but it is also an effect of the generally reduced activity in the vestibular system after a lesion and may act as protective mechanism in acute vertigo.
|
|
| 5. |
|
|
| 6. |
- Schalén, L, et al.
(författare)
-
Effects of intravenous diazepam and thiopental on the vestibulo-ocular reflex in man
- 1989
-
Ingår i: Acta Oto-Laryngologica. - : Informa UK Limited. - 1651-2251 .- 0001-6489. ; 108:S468, s. 9-165
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The effects of i.v. injection of diazepam 0.3 mg/kg and thiopental 6.0 mg/kg on vestibulo-ocular reflex (VOR) were studied in 9 healthy volunteers. One hour after injection of both diazepam and thiopental VOR gain was reduced and time constant shortened. Four hours after intravenous injection of diazepam the VOR gain was still significantly reduced and had not yet returned to control 8 h after injection. Although both drugs were detected in blood still 8 h after the injection, there were no longer significant effects on VOR. Moreover, individual values of VOR gain and time constant did not correlate with the blood concentrations of the drugs. Decrease of VOR gain and shortening of time constant after i.v. given diazepam and thiopental in man are interpreted as resulting from both specific effects on VOR and non-specific reduction of alertness.
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
|
|
