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- Klinthäll, Martin, 1967-
(författare)
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Kartläggning av invandrarföretagande i Norrköping och Linköping
- 2008
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Denna rapport har sammanställts mot bakgrund av att Norrköpings och Linköpings kommuner har uttryckt ett behov av en kartläggning av invandrarföretagandet i regionen. Kartläggningen är tänkt att tjäna som underlag för kommunerna i deras arbete för främjande av invandrares företagande i regionen, men även fungera som ett diskussionsmaterial för vidare forskning kring invandrarföretagandets lokala och regionala struktur. Uppdraget för rapporten är att dels kartlägga vilken typ av företag som drivs av invandrare och personer med utländsk bakgrund i kommunerna och dels att beskriva företagarnas bakgrundskarakteristika. Kartläggningen gäller uppgifter från det senaste år för vilket data finns tillgängliga, vilket i skrivande stund innebär år 2004.
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- Aad, G., et al.
(författare)
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- 2014
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Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; :11
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Tidskriftsartikel (refereegranskat)
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- Pan, Xiong-Fei, et al.
(författare)
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Circulating fatty acids and risk of gestational diabetes mellitus : prospective analyses in China
- 2021
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Ingår i: European Journal of Endocrinology. - : Bioscientifica. - 0804-4643 .- 1479-683X. ; 185:1, s. 87-97
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Tidskriftsartikel (refereegranskat)abstract
- Objective: We aimed to examine prospective associations between circulating fatty acids in early pregnancy and incident gestational diabetes mellitus (GDM) among Chinese pregnant women.Methods: Analyses were based on two prospective nested case-control studies conducted in western China (336 GDM cases and 672 matched controls) and central China (305 cases and 305 matched controls). Fasting plasma fatty acids in early pregnancy (gestational age at enrollment: 10.4 weeks(s.d., 2.0)) and 13.2 weeks (1.0), respectively) were determined by gas chromatography-mass spectrometry, and GDM was diagnosed based on the International Association of Diabetes in Pregnancy Study Groups criteria during 24-28 weeks of gestation. Multiple metabolic biomarkers (HOMA-IR (homeostatic model assessment for insulin resistance), HbA1c, c-peptide, high-sensitivity C-reactive protein, adiponectin, leptin, and blood lipids) were additionally measured among 672 non-GDM controls at enrollment.Results: Higher levels of saturated fatty acids (SFAs) 14:0 (pooled odds ratio, 1.41 for each 1-s.d. increase; 95% CI: 1.25, 1.59) and 16:0 (1.19; 1.05, 1.35) were associated with higher odds of GDM. Higher levels of n-6 polyunsaturated fatty acid (PUFA) 18:2n-6 were strongly associated with lower odds of GDM (0.69; 0.60, 0.80). In non-GDM pregnant women, higher SFAs 14:0 and 16:0 but lower n-6 PUFA 18:2n-6 were generally correlated with unfavorable metabolic profiles.Conclusions: We documented adverse associations of 14:0 and 16:0 but a protective association of 18:2n-6 with GDM among Chinese pregnant women. Our findings highlight the distinct roles of specific fatty acids in the onset of GDM.
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- Bouskova, Alzbeta, et al.
(författare)
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Improvement of separation and dewatering of activated sludge by using enhanced biological removal process over chemical phosphorus precipitation
- 2006
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Ingår i: Journal of Residuals Science and Technology. - 1544-8053. ; 3:3, s. 145-151
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Tidskriftsartikel (refereegranskat)abstract
- Samples from several WWTPs in Sweden, operating either with chemical precipitation of phosphorus, biological phosphorus removal or combination of the two, were analysed for separation and dewatering properties. The main parameters of interest were capillary suction time (CST), extracellular polymeric substances (EPS), metal ions concentration, filterability and compressibility of the sludge. Enhanced biological phosphorus removal (EBPR)-sludge is composed of compact flocs, while the chemical sludge contains higher colloids concentration in the liquid phase and retain water within the floc structure by stronger physical forces. These two phenomena reflected in the poorer filterability as well as compressibility of the chemical sludge in comparison to the sludge originating from biological phosphorus removal processes.
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| 10. |
- Mendelson, Michael M., et al.
(författare)
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Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease : A Mendelian Randomization Approach
- 2017
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Ingår i: PLoS Medicine. - : PUBLIC LIBRARY SCIENCE. - 1549-1277 .- 1549-1676. ; 14:1
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Tidskriftsartikel (refereegranskat)abstract
- Background The link between DNA methylation, obesity, and adiposity-related diseases in the general population remains uncertain. Methods and Findings We conducted an association study of body mass index (BMI) and differential methylation for over 400,000 CpGs assayed by microarray in whole-blood-derived DNA from 3,743 participants in the Framingham Heart Study and the Lothian Birth Cohorts, with independent replication in three external cohorts of 4,055 participants. We examined variations in whole blood gene expression and conducted Mendelian randomization analyses to investigate the functional and clinical relevance of the findings. We identified novel and previously reported BMI-related differential methylation at 83 CpGs that replicated across cohorts; BMI-related differential methylation was associated with concurrent changes in the expression of genes in lipid metabolism pathways. Genetic instrumental variable analysis of alterations in methylation at one of the 83 replicated CpGs, cg11024682 (intronic to sterol regulatory element binding transcription factor 1 [SREBF1]), demonstrated links to BMI, adiposity-related traits, and coronary artery disease. Independent genetic instruments for expression of SREBF1 supported the findings linking methylation to adiposity and cardiometabolic disease. Methylation at a substantial proportion (16 of 83) of the identified loci was found to be secondary to differences in BMI. However, the cross-sectional nature of the data limits definitive causal determination. Conclusions We present robust associations of BMI with differential DNA methylation at numerous loci in blood cells. BMI-related DNA methylation and gene expression provide mechanistic insights into the relationship between DNA methylation, obesity, and adiposity-related diseases.
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