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  • Ladds, MJGW, et al. (author)
  • Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
  • 2018
  • In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 9:1, s. 2071-
  • Journal article (peer-reviewed)abstract
    • The original PDF version of this Article listed the authors as “Marcus J.G.W. Ladds,” where it should have read “Marcus J. G. W. Ladds, Ingeborg M. M. van Leeuwen, Catherine J. Drummond et al.#”.Also in the PDF version, it was incorrectly stated that “Correspondence and requests for materials should be addressed to S. Lín.”, instead of the correct “Correspondence and requests for materials should be addressed to S. Laín.”This has been corrected in the PDF version of the Article. The HTML version was correct from the time of publication.
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  • Siefert, Andrew, et al. (author)
  • A global meta-analysis of the relative extent of intraspecific trait variation in plant communities
  • 2015
  • In: Ecology Letters. - : Wiley. - 1461-023X .- 1461-0248. ; 18:12, s. 1406-1419
  • Research review (peer-reviewed)abstract
    • Recent studies have shown that accounting for intraspecific trait variation (ITV) may better address major questions in community ecology. However, a general picture of the relative extent of ITV compared to interspecific trait variation in plant communities is still missing. Here, we conducted a meta-analysis of the relative extent of ITV within and among plant communities worldwide, using a data set encompassing 629 communities (plots) and 36 functional traits. Overall, ITV accounted for 25% of the total trait variation within communities and 32% of the total trait variation among communities on average. The relative extent of ITV tended to be greater for whole-plant (e.g. plant height) vs. organ-level traits and for leaf chemical (e.g. leaf N and P concentration) vs. leaf morphological (e.g. leaf area and thickness) traits. The relative amount of ITV decreased with increasing species richness and spatial extent, but did not vary with plant growth form or climate. These results highlight global patterns in the relative importance of ITV in plant communities, providing practical guidelines for when researchers should include ITV in trait-based community and ecosystem studies.
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  • Stewart, K. D., et al. (author)
  • On Cabbeling and Thermobaricity in the Surface Mixed Layer
  • 2017
  • In: Journal of Physical Oceanography. - 0022-3670 .- 1520-0485. ; 47:7, s. 1775-1787
  • Journal article (peer-reviewed)abstract
    • The surface mixed layer (ML) governs atmosphere-ocean fluxes, and thereby affects Earth's climate. Accurate representation of ML processes in ocean models remains a challenge, however. The O(100) m deep ML exhibits substantial horizontal thermohaline gradients, despite being near-homogenous vertically, making it an ideal location for processes that result from the nonlinearity of the equation of state, such as cabbeling and thermobaricity. Traditional approaches to investigate these processes focus on their roles in interior water-mass transformation and are ill suited to examine their influence on the ML. However, given the climatic significance of the ML, quantifying the extent to which cabbeling and thermobaricity influence the ML density field offers insight into improving ML representations in ocean models. A recent simplified equation of state of seawater allows the local effects of cabbeling and thermobaric processes in the ML to be expressed analytically as functions of the local temperature gradient and ML depth. These simplified expressions are used to estimate the extent to which cabbeling and thermobaricity contribute to local ML density differences. These estimates compare well with values calculated directly using the complete nonlinear equation of state. Cabbeling and thermobaricity predominantly influence the ML density field poleward of 30 degrees. Mixed layer thermobaricity is basin-scale and winter intensified, while ML cabbeling is perennial and localized to intense, zonally coherent regions associated with strong temperature fronts, such as the Antarctic Circumpolar Current and the Kuroshio and Gulf Stream Extensions. For latitudes between 40 degrees and 50 degrees in both hemispheres, the zonally averaged effects of ML cabbeling and ML thermobaricity can contribute on the order of 10% of the local ML density difference.
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