SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(McCarthy R. J.) srt2:(2020-2024)"

Sökning: WFRF:(McCarthy R. J.) > (2020-2024)

  • Resultat 1-10 av 95
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Kanai, M, et al. (författare)
  • 2023
  • swepub:Mat__t
  •  
2.
  • Niemi, MEK, et al. (författare)
  • 2021
  • swepub:Mat__t
  •  
3.
  • Glasbey, JC, et al. (författare)
  • 2021
  • swepub:Mat__t
  •  
4.
  •  
5.
  •  
6.
  •  
7.
  •  
8.
  • Ramdas, S., et al. (författare)
  • A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
  • 2022
  • Ingår i: American Journal of Human Genetics. - : Elsevier BV. - 0002-9297 .- 1537-6605. ; 109:8, s. 1366-1387
  • Tidskriftsartikel (refereegranskat)abstract
    • A major challenge of genome-wide association studies (GWASs) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ancestries with a wide array of functional genomic datasets to discover regulatory mechanisms underlying lipid associations. We first prioritize lipid-associated genes with expression quantitative trait locus (eQTL) colocalizations and then add chromatin interaction data to narrow the search for functional genes. Polygenic enrichment analysis across 697 annotations from a host of tissues and cell types confirms the central role of the liver in lipid levels and highlights the selective enrichment of adipose-specific chromatin marks in high-density lipoprotein cholesterol and triglycerides. Overlapping transcription factor (TF) binding sites with lipid-associated loci identifies TFs relevant in lipid biology. In addition, we present an integrative framework to prioritize causal variants at GWAS loci, producing a comprehensive list of candidate causal genes and variants with multiple layers of functional evidence. We highlight two of the prioritized genes, CREBRF and RRBP1, which show convergent evidence across functional datasets supporting their roles in lipid biology.
  •  
9.
  •  
10.
  • Buchanan, E. M., et al. (författare)
  • The Psychological Science Accelerator's COVID-19 rapid-response dataset
  • 2023
  • Ingår i: Scientific Data. - : Springer Science and Business Media LLC. - 2052-4463. ; 10:1
  • Tidskriftsartikel (refereegranskat)abstract
    • In response to the COVID-19 pandemic, the Psychological Science Accelerator coordinated three large-scale psychological studies to examine the effects of loss-gain framing, cognitive reappraisals, and autonomy framing manipulations on behavioral intentions and affective measures. The data collected (April to October 2020) included specific measures for each experimental study, a general questionnaire examining health prevention behaviors and COVID-19 experience, geographical and cultural context characterization, and demographic information for each participant. Each participant started the study with the same general questions and then was randomized to complete either one longer experiment or two shorter experiments. Data were provided by 73,223 participants with varying completion rates. Participants completed the survey from 111 geopolitical regions in 44 unique languages/dialects. The anonymized dataset described here is provided in both raw and processed formats to facilitate re-use and further analyses. The dataset offers secondary analytic opportunities to explore coping, framing, and self-determination across a diverse, global sample obtained at the onset of the COVID-19 pandemic, which can be merged with other time-sampled or geographic data.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 95
Typ av publikation
tidskriftsartikel (83)
forskningsöversikt (6)
annan publikation (2)
konferensbidrag (1)
Typ av innehåll
refereegranskat (80)
övrigt vetenskapligt/konstnärligt (12)
Författare/redaktör
McCarthy, Mark I (17)
Mahajan, Anubha (14)
Franks, Paul W. (13)
Walker, M (11)
Kaprio, J (10)
Mahajan, A. (10)
visa fler...
Landén, Mikael, 1966 (10)
Pedersen, Oluf (10)
Laakso, M. (10)
Loos, RJF (9)
Lind, Lars (9)
Laakso, Markku (9)
Hansen, Torben (9)
McCarthy, MI (9)
Esko, T (9)
Erdmann, J. (8)
McCarthy, R. (8)
Langenberg, C. (8)
Groop, Leif (8)
Franke, A (8)
Patel, A (8)
Bauer, M (8)
Palotie, A (8)
Campbell, A (8)
Hattersley, Andrew T (8)
Kurbasic, A. (8)
Wilson, JF (8)
Hottenga, JJ (7)
Clark, M. (7)
Okada, Y. (7)
Kim, YJ (7)
Chen, Z. (7)
Yang, J. (7)
Ishii, T. (7)
McCarthy, M. (7)
Tuomi, T. (7)
King, D. (7)
Hoffmann, P (7)
Gudnason, V (7)
Hashimoto, R (7)
Sattar, N. (7)
Timpson, NJ (7)
Marz, W. (7)
Snieder, H. (7)
Campbell, H (7)
Vieta, E (7)
Vinuela, Ana (7)
Hansen, T. (7)
Walker, Mark (7)
Palmer, CNA (7)
visa färre...
Lärosäte
Karolinska Institutet (55)
Lunds universitet (29)
Göteborgs universitet (27)
Uppsala universitet (16)
Kungliga Tekniska Högskolan (12)
Umeå universitet (9)
visa fler...
Stockholms universitet (8)
Chalmers tekniska högskola (5)
Örebro universitet (3)
Linköpings universitet (3)
Handelshögskolan i Stockholm (2)
Högskolan Väst (1)
Karlstads universitet (1)
Högskolan Dalarna (1)
Sveriges Lantbruksuniversitet (1)
Sophiahemmet Högskola (1)
visa färre...
Språk
Engelska (95)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (57)
Naturvetenskap (15)
Teknik (5)
Samhällsvetenskap (5)
Humaniora (2)
Lantbruksvetenskap (1)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy