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Träfflista för sökning "WFRF:(McGregor P. J.) srt2:(2000-2004)"

Search: WFRF:(McGregor P. J.) > (2000-2004)

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1.	Lopez-Sendon, J., et al. (author) [Expert Consensus document on angiotensin converting enzyme inhibitors in cardiovascular disease] 2004 In: Revista espanola de cardiologia. - 0300-8932. ; 57:12, s. 1213-32 Research review (peer-reviewed)
2.	Giorgi, F., et al. (author) Chapter 10 of the IPCC TAR (Climate Change 2001: The Scientific Basis) 2001 In: Chapter 10-Regional Climate Information Evaluation and Projections, Cambridge University Press, Cambridge, UK. ; , s. 584-638 Book chapter (other academic/artistic)
3.	Kirby, A J, et al. (author) Gemini surfactants: New synthetic vectors for gene transfection 2003 In: Angewandte Chemie International Edition in English. - : Wiley. - 0570-0833 .- 1433-7851 .- 1521-3773. ; 42:13, s. 1448-1457 Research review (peer-reviewed)abstract The superior surfactant properties of cationic gemini surfactants are applied to the complex problem of introducing genes into cells. Of almost 250 new compounds tested, of some 20 different structural types, a majority showed very good transfection activity in vitro. The surfactant is shown to bind and compact DNA efficiently, and structural studies and calculations provide a working picture of the lipoplex formed. The lipoplex can penetrate the outer membranes of many cell types, to appear in the cytoplasm encapsulated within endosomes. Escape from the endosome - a key step for transfection - may be controlled by changes in the aggregation behavior of the lipoplex as the pH falls. The evidence suggests that DNA may be released from the lipoplex before entry into the nucleus, where the new gene can be expressed with high efficiency.

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Type of publication: research review (2); book chapter (1)

Type of content: peer-reviewed (2); other academic/artistic (1)

Author/Editor: Ferrari, R. (1); Werner, P. (1); Christensen, J (1); Kjekshus, J (1); Jones, R. (1); Swedberg, Karl, 1944 (1); show more...; Tognoni, G. (1); Maggioni, A. P. (1); Tendera, M (1); Kober, L. (1); Chen, Deliang, 1961 (1); Xue, Y. (1); Widmann, M (1); Morais, J (1); Walsh, K (1); Blomström-Lundqvist, ... (1); Lal, M. (1); Rinke, A. (1); Dethloff, K. (1); Laprise, R. (1); Wallentin, Lars (1); Lindahl, Bertil (1); Söderman, Olle (1); Klein, W. (1); Castro, M. (1); Crane, R (1); Wild, M. (1); Hanssen-Bauer, I (1); McMurray, J. (1); Kato, H (1); Cramer, W. (1); Giorgi, F. (1); Nieminen, M (1); Murphy, J (1); Lopez-Sendon, J (1); Simoons, M (1); Dean, V (1); Clement, D. (1); Fu, C. (1); Benestad, R. (1); Fox, K A (1); Thygesen, K (1); Budaj, A (1); Lekakis, J (1); May, W (1); Jack, C (1); Ardissino, D (1); Mancia, G (1); Torp-Pedersen, C (1); Blanc, J. J. (1); show less...

University: University of Gothenburg (2); Uppsala University (1); Lund University (1)

Language: English (3)

Research subject (UKÄ/SCB): Natural sciences (2); Medical and Health Sciences (1)

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