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| 2. |
- Reichenberg, Monica, et al.
(författare)
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The social practice of reading and writing instruction in schools for intellectually disabled pupils
- 2013
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Ingår i: Journal of Special Education and Rehabilitation. - Skopje : Faculty of Philosophy, Institute of Special Education and Rehabilitation. - 1857-663X .- 1409-6099. ; 14:3-4, s. 43-60
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Tidskriftsartikel (refereegranskat)abstract
- In Sweden, schooling for children who are regarded as intellectually disabled is organised in a special school, Särskolan. The overall aim of this article was to investigate the teachers’ attitudes towards the social practice of reading and writing instruction in Särskolan. Therefore, 40 teachers from Northern Sweden were sampled for the empirical study. The teachers were asked to fill out a questionnaire. One of the findings was that the teachers reported different attitudes towards the social practice of reading and writing instruction. Another finding was that the teachers reported they did not practice the documentation of reading and writing difficulties. Furthermore, the practice of documentation was associated with professional competence in reading and writing literacy. The study suggests that literacy education did have an effect on teachers’ attitudes towards their practice of documenting. However, the openness towards organizational learning was polarized, and consequently, it produced a threshold for change. Accordingly, more studies are necessary for further description and explanation of the complexities of the present findings.
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| 3. |
- Abghari, Shahrooz, et al.
(författare)
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District Heating Substation Behaviour Modelling for Annotating the Performance
- 2020
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Ingår i: Communications in Computer and Information Science. - Cham : Springer. - 9783030438869 ; , s. 3-11
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Konferensbidrag (refereegranskat)abstract
- In this ongoing study, we propose a higher order data mining approach for modelling district heating (DH) substations’ behaviour and linking operational behaviour representative profiles with different performance indicators. We initially create substation’s operational behaviour models by extracting weekly patterns and clustering them into groups of similar patterns. The built models are further analyzed and integrated into an overall substation model by applying consensus clustering. The different operational behaviour profiles represented by the exemplars of the consensus clustering model are then linked to performance indicators. The labelled behaviour profiles are deployed over the whole heating season to derive diverse insights about the substation’s performance. The results show that the proposed method can be used for modelling, analyzing and understanding the deviating and sub-optimal DH substation’s behaviours. © 2020, Springer Nature Switzerland AG.
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| 5. |
- Ball, William T., et al.
(författare)
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Reconciling differences in stratospheric ozone composites
- 2017
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Ingår i: Atmospheric Chemistry And Physics. - : Copernicus GmbH. - 1680-7316 .- 1680-7324. ; 17:20, s. 12269-12302
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Tidskriftsartikel (refereegranskat)abstract
- Observations of stratospheric ozone from multiple instruments now span three decades; combining these into composite datasets allows long-term ozone trends to be estimated. Recently, several ozone composites have been published, but trends disagree by latitude and altitude, even between composites built upon the same instrument data. We confirm that the main causes of differences in decadal trend estimates lie in (i) steps in the composite time series when the instrument source data changes and (ii) artificial sub-decadal trends in the underlying instrument data. These artefacts introduce features that can alias with regressors in multiple linear regression (MLR) analysis; both can lead to inaccurate trend estimates. Here, we aim to remove these artefacts using Bayesian methods to infer the underlying ozone time series from a set of composites by building a joint-likelihood function using a Gaussian-mixture density to model outliers introduced by data artefacts, together with a data-driven prior on ozone variability that incorporates knowledge of problems during instrument operation. We apply this Bayesian self-calibration approach to stratospheric ozone in 10 degrees bands from 60 degrees S to 60 degrees N and from 46 to 1 hPa (similar to 21-48 km) for 1985-2012. There are two main outcomes: (i) we independently identify and confirm many of the data problems previously identified, but which remain unaccounted for in existing composites; (ii) we construct an ozone composite, with uncertainties, that is free from most of these problems - we call this the BAyeSian Integrated and Consolidated (BASIC) composite. To analyse the new BASIC composite, we use dynamical linear modelling (DLM), which provides a more robust estimate of long-term changes through Bayesian inference than MLR. BASIC and DLM, together, provide a step forward in improving estimates of decadal trends. Our results indicate a significant recovery of ozone since 1998 in the upper stratosphere, of both northern and southern midlatitudes, in all four composites analysed, and particularly in the BASIC composite. The BASIC results also show no hemispheric difference in the recovery at midlatitudes, in contrast to an apparent feature that is present, but not consistent, in the four composites. Our overall conclusion is that it is possible to effectively combine different ozone composites and account for artefacts and drifts, and that this leads to a clear and significant result that upper stratospheric ozone levels have increased since 1998, following an earlier decline.
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- Pérez-Penichet, Carlos, et al.
(författare)
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A Fast Carrier Scheduling Algorithm for Battery-free Sensor Tags in Commodity Wireless Networks
- 2020
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Ingår i: IEEE INFOCOM 2020 - IEEE Conference on Computer Communications. - : IEEE. - 9781728164120 ; , s. 994-1003
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Konferensbidrag (refereegranskat)abstract
- New battery-free sensor tags that interoperate with unmodified standard IoT devices and protocols can extend a sensor network’s capabilities in a scalable and cost-effective manner. The tags achieve battery-free operation through backscatter-related techniques, while the standard IoT devices avoid additional dedicated infrastructure by providing the unmodulated carrier that tags need to communicate. However, this approach requires coordination between devices transmitting, receiving and generating carrier, adds extra latency and energy consumption to already constrained devices, and increases interference and contention in the shared spectrum. We present a scheduling mechanism that optimizes the use of carrier generators, minimizing any disruptions to the regular nodes. We employ timeslots to coordinate the unmodulated carrier while minimizing latency, energy consumption and overhead radio emissions. We propose an efficient scheduling algorithm that parallelizes communications with battery-free tags when possible and shares carriers among multiple tags concurrently. In our evaluation we demonstrate the feasibility and reliability of our approach in testbed experiments. We find that we can significantly reduce the excess latency and energy consumption caused by the addition of sensor tags when compared to sequential interrogation. We show that the gains tend to improve with the network size and that our solution is close to optimal on average.
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| 8. |
- Alcantara, Ricardo, et al.
(författare)
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Metal-Ion Intercalation Mechanisms in Vanadium Pentoxide and Its New Perspectives
- 2023
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Ingår i: Nanomaterials. - : MDPI. - 2079-4991. ; 13:24
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Forskningsöversikt (refereegranskat)abstract
- The investigation into intercalation mechanisms in vanadium pentoxide has garnered significant attention within the realm of research, primarily propelled by its remarkable theoretical capacity for energy storage. This comprehensive review delves into the latest advancements that have enriched our understanding of these intricate mechanisms. Notwithstanding its exceptional storage capacity, the compound grapples with challenges arising from inherent structural instability. Researchers are actively exploring avenues for improving electrodes, with a focus on innovative structures and the meticulous fine-tuning of particle properties. Within the scope of this review, we engage in a detailed discussion on the mechanistic intricacies involved in ion intercalation within the framework of vanadium pentoxide. Additionally, we explore recent breakthroughs in understanding its intercalation properties, aiming to refine the material's structure and morphology. These refinements are anticipated to pave the way for significantly enhanced performance in various energy storage applications.
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| 9. |
- Giovannucci, Tatiana A., et al.
(författare)
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Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
- 2022
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Ingår i: Autophagy. - : Taylor & Francis. - 1554-8627 .- 1554-8635. ; 18:7, s. 1486-1502
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Tidskriftsartikel (refereegranskat)abstract
- The ubiquitin-proteasome system (UPS) and macroautophagy/autophagy are the main proteolytic systems in eukaryotic cells for preserving protein homeostasis, i.e., proteostasis. By facilitating the timely destruction of aberrant proteins, these complementary pathways keep the intracellular environment free of inherently toxic protein aggregates. Chemical interference with the UPS or autophagy has emerged as a viable strategy for therapeutically targeting malignant cells which, owing to their hyperactive state, heavily rely on the sanitizing activity of these proteolytic systems. Here, we report on the discovery of CBK79, a novel compound that impairs both protein degradation by the UPS and autophagy. While CBK79 was identified in a high-content screen for drug-like molecules that inhibit the UPS, subsequent analysis revealed that this compound also compromises autophagic degradation of long-lived proteins. We show that CBK79 induces non-canonical lipidation of MAP1LC3B/LC3B (microtubule-associated protein 1 light chain 3 beta) that requires ATG16L1 but is independent of the ULK1 (unc-51 like autophagy activating kinase 1) and class III phosphatidylinositol 3-kinase (PtdIns3K) complexes. Thermal preconditioning of cells prevented CBK79-induced UPS impairment but failed to restore autophagy, indicating that activation of stress responses does not allow cells to bypass the inhibitory effect of CBK79 on autophagy. The identification of a small molecule that simultaneously impairs the two main proteolytic systems for protein quality control provides a starting point for the development of a novel class of proteostasis-targeting drugs.
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