SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Messmer M.) srt2:(2010-2014)"

Sökning: WFRF:(Messmer M.) > (2010-2014)

  • Resultat 1-10 av 13
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Aad, G., et al. (författare)
  • 2010
  • swepub:Mat__t
  •  
2.
  • Aad, G., et al. (författare)
  • 2010
  • swepub:Mat__t
  •  
3.
  • Aad, G., et al. (författare)
  • 2011
  • swepub:Mat__t
  •  
4.
  • Aad, G., et al. (författare)
  • 2010
  • swepub:Mat__t
  •  
5.
  • 2011
  • swepub:Mat__t
  •  
6.
  • Aad, G., et al. (författare)
  • 2010
  • swepub:Mat__t
  •  
7.
  •  
8.
  •  
9.
  • Aliev, M., et al. (författare)
  • A forward silicon strip system for the ATLAS HL-LHC upgrade
  • 2013
  • Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 730, s. 210-214
  • Tidskriftsartikel (refereegranskat)abstract
    • In the year 2022 an upgrade of the Large Hadron Collider (LHC) is planned to increase the luminosity such that an integrated luminosity of L-int similar to 3000 fb(-1) can be accumulated by 2030 [1]. The radiation damage of the present inner tracker at this date and the high track density of the High Luminosity LHC (HL-LHC) require an upgrade of the inner tracker of the ATLAS (A Toroidal LHC ApparatuS) experiment. A new integration concept will be used: the readout electronics is directly glued on the strip surface of the silicon sensors and the sensors are glued to a support structure. For the barrel region this structure is referred to as a Stave and for the end-cap region it is referred to as a Petal. For tests a smaller version, the Petalet, will be build with two design concepts. In this article the construction method is explained and first hybrid test results for one Petalet sensor are presented.
  •  
10.
  • Saenz, R., et al. (författare)
  • Activity of the HMGB1-derived immunostimulatory peptide Hp91 resides in the helical C-terminal portion and is enhanced by dimerization
  • 2014
  • Ingår i: Molecular Immunology. - : Elsevier. - 0161-5890 .- 1872-9142. ; 57:2, s. 191-199
  • Tidskriftsartikel (refereegranskat)abstract
    • We have previously shown that an 18 amino acid long peptide, named Hp91, whose sequence corresponds to a region within the endogenous protein HMGB1, activates dendritic cells (DCs) and acts as adjuvant in vivo by potentiating Thl -type antigen-specific immune responses. We analyzed the structure-function relationship of the Hp91 peptide to investigate the amino acids and structure responsible for immune responses. We found that the cysteine at position 16 of Hp91 enabled formation of reversible peptide dimmers, monomer and dimmer were compared for DC binding and activation. Stable monomers and dimers were generated using a maleimide conjugation reaction. The dimer showed enhanced ability to bind to and activate DCs. Furthermore, the C-terminal 9 amino acids of Hp91, named UC1018 were sufficient for DC binding and Circular dichroism showed that UC1018 assumes an alpha-helical structure. The ninemer peptide UC1018 induced more potent antigen-specific CTL responses in vivo as compared to Hp91 and it protected mice from tumor development when used in a prophylactic vaccine setting. We have identified a short alpha helical peptide that acts as potent adjuvant inducing protective immune responses in vivo.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 13

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy