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Can We Use Metabolo...
Can We Use Metabolomics to Understand Changes to Gut Microbiota Populations and Function? A Nutritional Perspective
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- Moco, S. (författare)
- Nestle S.A.
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- Ross, Alastair, 1976 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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Nestle SA. Chalmers tekniska högskola (creator_code:org_t)
- 2014-09-19
- 2015
- Engelska.
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Ingår i: Molecular and Integrative Toxicology. - London : Springer London. ; , s. 83-108
- Relaterad länk:
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https://research.cha...
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visa fler...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Food is an integral part of human life, and the composition of our diet is an important determinant of our health and well-being. Food is also the main source of energy and nutrients for the gut microbiota, the 100 trillion cells that coexist inside us. The impact of macronutrients (protein, fat, carbohydrates, and fiber) and specific non-nutrient food components (polyphenols) will be reviewed in the context of gut microbial function and interaction with the host. Colonic microbiota provides diverse enzymatic activities differing from our own, which lead to the production of metabolites essential for key metabolic functions, including carbohydrate and amino acid metabolism. Certain gut metabolites are specific to microbial activity and confer functionalities beyond energy production, such as signalling cascades across cells, tissues, and organs. Metabolomics has proven to be a useful tool to measure the effects of food on the gut microbiota and its interaction with host metabolism.
Ämnesord
- NATURVETENSKAP -- Biologi -- Cellbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Cell Biology (hsv//eng)
- LANTBRUKSVETENSKAPER -- Lantbruksvetenskap, skogsbruk och fiske -- Livsmedelsvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Agriculture, Forestry and Fisheries -- Food Science (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Nyckelord
- Choline
- Fiber
- Phase II metabolism
- Pathways
- Digestion
- Metabolism
- Nutrition
- Metabolomics
- Whole-grain cereals
- p-Cresol sulfate
- Chocolate
- Carnitine
- Branched-chain fatty acids
- Hippurate
- Colon
- Trimethylamine oxide
- Microbiota
- Indole metabolites
- Food
- Butyrate
- Fat
- Short-chain fatty acids
- Protein
- Phenolic and phenyl metabolites
- Gut-liver
- Prebiotics
- Gut-brain
- Intestine
- Metabolomics
- One carbon metabolism
- Diet
- Polyphenols
- Gut
- Carbohydrate
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