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Träfflista för sökning "WFRF:(Monti C.) srt2:(2010-2014)"

Sökning: WFRF:(Monti C.) > (2010-2014)

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  • Farias, Fabricio S., et al. (författare)
  • Green backhauling for heterogeneous mobile access networks : What are the challenges?
  • 2013
  • Ingår i: 2013 9th International Conference on Information, Communications and Signal Processing (ICICS). - : IEEE Computer Society. - 9781479904334 ; , s. 6782868-
  • Konferensbidrag (refereegranskat)abstract
    • Heterogeneous network (HetNet) deployment strategies have the potential to improve the energy efficiency of mobile access networks. One key aspect to consider in HetNets is the impact of the power consumption of the backhaul, i.e., the overall energy efficiency of a HetNet deployment is affected by the backhaul technology and architecture. This paper presents a preliminary assessment of the design challenges of a future green backhaul segment for a HetNet deployment. The study is based on the analysis of the medium term future outlook (i.e., between now and the year 2025) of the main technologies used in todays'* backhaul networks (i.e., fiber, microwave and copper). It can be concluded that, even if there arc no doubts that both microwave and fiber will be predominately used in the future, the possible migration paths leading to such fiber- and microwave-dominated scenarios might be different, depending on factors such as spectrum and license costs, time to deployment, availability of equipment, and required Quality of Service (QoS) levels.
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  • Monti, Paolo, et al. (författare)
  • Green mobile backhaul in heterogeneous wireless deployments
  • 2013
  • Ingår i: Asia Communications and Photonics Conference, ACP 2013. - Washington, D.C. : Optical Society of America.
  • Konferensbidrag (refereegranskat)abstract
    • This tutorial first introduces and describes different backhaul technological and architectural options (i.e., fiber-, microwave-, and copper-based), then it discusses their impact on the energy consumption of current and future heterogeneous mobile wireless access deployments.
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  • Natalino, C., et al. (författare)
  • A relocation-based heuristic for restoring optical cloud services
  • 2014
  • Ingår i: 2014 13th International Conference on Optical Communications and Networks. - 9781479972180
  • Konferensbidrag (refereegranskat)abstract
    • Optical clouds allow for an integrated management of optical transport and cloud resources (e.g., storage and computing resources running on datacenters). In this paradigm the concept of service relocation (i.e., the ability to re-allocate to a different datacenter node an already provisioned cloud service) offers a new way to restore the network upon failure. This paper presents a heuristic (called H-RELOCATION) based on the service relocation concept to be used for the dynamic restoration of optical cloud services. Upon the occurrence of a network failure, H-RELOCATION solves the routing and resource (i.e., transport plus cloud) allocation problem for each disrupted cloud service allowing, if necessary, to relocate some cloud services to different datacenter nodes. The proposed strategy is benchmarked against two optimal restoration strategies based on Integer Linear Programming (ILP) formulations, the first one without and the second one with the ability to use the service relocation idea. Simulation results show that H-RELOCATION offers performance (i.e., blocking probability, restorability levels and number of required relocations) very close to the optimum, offering on the other hand, a significant reduction in the processing time required for each successfully restored cloud service.
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  • Padmanabhan, Sandosh, et al. (författare)
  • Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension
  • 2010
  • Ingår i: PLoS Genetics. - : Public Library of Science (PLoS). - 1553-7404. ; 6:10
  • Tidskriftsartikel (refereegranskat)abstract
    • Hypertension is a heritable and major contributor to the global burden of disease. The sum of rare and common genetic variants robustly identified so far explain only 1%-2% of the population variation in BP and hypertension. This suggests the existence of more undiscovered common variants. We conducted a genome-wide association study in 1,621 hypertensive cases and 1,699 controls and follow-up validation analyses in 19,845 cases and 16,541 controls using an extreme case-control design. We identified a locus on chromosome 16 in the 59 region of Uromodulin (UMOD; rs13333226, combined P value of 3.6x10(-11)). The minor G allele is associated with a lower risk of hypertension (OR [95% CI]: 0.87 [0.84-0.91]), reduced urinary uromodulin excretion, better renal function; and each copy of the G allele is associated with a 7.7% reduction in risk of CVD events after adjusting for age, sex, BMI, and smoking status (H.R. = 0.923, 95% CI 0.860-0.991; p = 0.027). In a subset of 13,446 individuals with estimated glomerular filtration rate (eGFR) measurements, we show that rs13333226 is independently associated with hypertension (unadjusted for eGFR: 0.89 [0.83-0.96], p = 0.004; after eGFR adjustment: 0.89 [0.83-0.96], p = 0.003). In clinical functional studies, we also consistently show the minor G allele is associated with lower urinary uromodulin excretion. The exclusive expression of uromodulin in the thick portion of the ascending limb of Henle suggests a putative role of this variant in hypertension through an effect on sodium homeostasis. The newly discovered UMOD locus for hypertension has the potential to give new insights into the role of uromodulin in BP regulation and to identify novel drugable targets for reducing cardiovascular risk.
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