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1.
  • Weinstein, John N., et al. (författare)
  • The cancer genome atlas pan-cancer analysis project
  • 2013
  • Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:10, s. 1113-1120
  • Forskningsöversikt (refereegranskat)abstract
    • The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. © 2013 Nature America, Inc. All rights reserved.
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2.
  • Moore, Jason W., 1971- (författare)
  • 'Amsterdam is Standing on Norway', Part I : The Alchemy of Capital, Empire and Nature in the Diaspora of Silver, 1545–1648
  • 2010
  • Ingår i: Journal of Agrarian Change. - 1471-0358 .- 1471-0366. ; 10:1, s. 33-68
  • Tidskriftsartikel (refereegranskat)abstract
    • In the first of two essays in this Journal, I seek to unify the historicalgeography of early modern ‘European expansion’ (Iberia and Latin America)with the environmental history of the ‘transition to capitalism’ (northwestern Europe). The expansion of Europe’s overseas empires and the transitions to capitalism within Europe were differentiated moments within the geographicalexpansion of commodity production and exchange – what I call the commodityfrontier. This essay is developed in two movements. Beginning with a conceptual and methodological recasting of the historical geography of the rise of capitalism,I offer an analytical narrative that follows the early modern diaspora of silver.This account follows the political ecology of silver production and trade from the Andes to Spain in Braudel’s ‘second’ sixteenth century (c. 1545–1648). In highlighting the Ibero-American moment of this process in the present essay, Icontend that the spectacular reorganization of Andean space and the progressive dilapidation of Spain’s real economy not only signified the rise and demise of a trans-Atlantic, Iberian ecological regime, but also generated the historicallynecessary conditions for the unprecedented concentration of accumulation andcommodity production in the capitalist North Atlantic in the centuries thatfollowed.
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4.
  • Moore, Jason W., 1971- (författare)
  • Ecology and the accumulation of capital : thinking capitalism through the web of life
  • 2011
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • Capitalism as world-ecology is an effort to move from the “environmental history of” capitalism, or modernity, or the world market, to capitalism AS environmental history. Financial crises, for instance, are not social or economic crises that make their footprint on the rest of nature; they are crises of a key moment of capitalism’s symbolic and material ordering of the relation between humans and the rest of nature. This dialectical alternative views the great movements of modern world history – industrial and agricultural revolutions, successive new imperialisms, the development of the world market – as socio-ecological projects and processes, aimed at reconfiguring nature-society relations. ‘Nature,’ no longer a passive substance upon which humanity leaves its footprint, becomes an active bundle of relations, formed and re-formed through the historically- and geographically-specific movements of humans, with the rest of nature. This entails more than a catalogue of capitalism’s biophysical depredations. It calls for new synthesis that locates the accumulation of capital, the production of nature, and pursuit of power in a singular and differentiated whole. This perspective begins from the premise that capitalism does not act upon nature so much as develop through nature-society relations. Capitalism does not have an ecological regime; it is an ecological regime.
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5.
  • Moore, Jason W., 1971- (författare)
  • Ecology, Capital, and the Nature of Our Times : Accumulation & Crisis in the Capitalist World-Ecology
  • 2011
  • Ingår i: Journal of World-Systems Research. - 1076-156X. ; 17:1, s. 108-147
  • Tidskriftsartikel (refereegranskat)abstract
    • In this essay, I elaborate the possibilities for a unified theory of historical capitalism – one that views the accumulation of capital and the production of nature (humans included!) as dialectically constituted. In this view, the modern world-system is a capitalist world-ecology, a world-historical matrix of human- and extra-human nature premised on endless commodification. The essay is organized in three movements. I begin by arguing for a reading of modernity’s “interdependent master processes” (Tilly) as irreducibly socio-ecological. Capitalism does not develop upon global nature so much as it emerges through the messy and contingent relations of humans with the rest of nature. Second, the paper engages Giovanni Arrighi’s handling of time, space, and accumulation in The Long Twentieth Century. I highlight Arrighi’s arguments for a “structurally variant” capitalism, and the theory of organizational revolutions, as fruitful ways to construct a theory of capitalism as world-ecology. I conclude with a theory of accumulation and its crises as world-ecological process, building out from Marx’s “general law” of underproduction. Historically, capitalism has been shaped by a dialectic of underproduction (too few inputs) and overproduction (too many commodities). Today, capitalism is poised for a re-emergence of underproduction crises, characterized by the insufficient flow of cheap food, fuel, labor, and energy to the productive circuit of capital. Far from the straightforward expression of “overshoot” and “peak everything,” the likely resurgence of underproduction crises is an expression of capitalism’s longue durée tendency to undermine its conditions of reproduction. The world-ecological limit of capital, in other words, is capital itself.
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6.
  • Moore, Jason W., 1971- (författare)
  • Introduction : The World-Historical Imagination
  • 2011
  • Ingår i: Journal of World-Systems Research. - Riverside, Calif. : Institute for Research on World-Systems. - 1076-156X. ; 17:1, s. 1-3
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • This article is the editor's introduction to the special issue of the Journal of World-Systems Research, entitled The World-Historical Imagination: Giovanni Arrighi's The Long Twentieth Century in Prospect and Retrospect.
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7.
  • Moore, Jason W., 1971- (författare)
  • The end of the road? : agricultural revolutions in the capitalist World-ecology, 1450-2010
  • 2010
  • Ingår i: Journal of Agrarian Change. - : Wiley - Blackwell. - 1471-0358 .- 1471-0366. ; 10:3, s. 389-413
  • Tidskriftsartikel (refereegranskat)abstract
    • Does the present socio-ecological impasse – captured in popular discussions of the ‘end’ of cheap food and cheap oil – represent the latest in a long history of limits and crises that have been transcended by capital, or have we arrived at an epochal turning point in the relation of capital, capitalism and agricultural revolution? For the better part of six centuries, the relation between world capitalism and agriculture has been a remarkable one. Every great wave of capitalist development has been paved with ‘cheap’ food. Beginning in the long sixteenth century, capitalist agencies pioneered successive agricultural revolutions, yielding a series of extraordinary expansions of the food surplus. This paper engages the crisis of neoliberalism today, and asks: Is another agricultural revolution, comparable to those we have known in the history of capitalism, possible? Does the present conjuncture represent a developmental crisis of capitalism that can be resolved by establishing new agro-ecological conditions for another long wave of accumulation, or are we now witnessing an epochal crisis of capitalism? These divergent possibilities are explored from a perspective that views capitalism as ‘world-ecology’, joining together the accumulation of capital and the production of nature in dialectical unity.
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8.
  • Moore, Jason W., 1971- (författare)
  • The Socio-Ecological Crises of Capitalism
  • 2011
  • Ingår i: Capital and its Discontents. - Oakland : PM Press. - 9781552663943 ; , s. 136-152
  • Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
    • I think the lesson is that Malthus was wrong because he took the problem of limits outside of history, outside the history that women and men make in the modern world. So the issue is not that there is no scarcity — of course, capitalism is a system that is premised on induced scarcity. That’s why markets in the capitalist era function the way that they do. So I think the mistake of the left has been in a certain reluctance to deal with the problems of scarcity, or in some cases back into an embrace of a neo-Malthusian scarcity mentality in which there are these “natural limits” that are outside of how capitalism functions historically as an ecological regime.
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9.
  • Moore, Jason W., 1971- (författare)
  • Transcending the Metabolic Rift : a theory of crises in the capitalist world-ecology
  • 2011
  • Ingår i: The Journal of Peasant Studies. - : Informa UK Limited. - 0306-6150 .- 1743-9361. ; 38:1, s. 1-46
  • Tidskriftsartikel (refereegranskat)abstract
    • The theory of metabolic rift is among the most dynamic perspectives in critical environmental studies today. This essay argues that the problem with the metabolic rift perspective is not that it goes too far, but that it does not go far enough. I take a 'use and transcend' approach that takes metabolic rift theory as an indispensable point of departure in building a unified theory of capitalist development - one that views the accumulation of capital, the pursuit of power, and the production of nature as differentiated moments within the singularity of historical capitalism. My response unfolds through two related arguments. First, the theory of metabolic rift, as elaborated by Foster, Clark, and York, is grounded in a Cartesian binary that locates biophysical crises in one box, and accumulation crises in another. This views biophysical problems as consequences of capitalist development, but not constitutive of capitalism as a historical system. The second part of this essay moves from critique to synthesis. Drawing out the value-theoretical implications of the metabolic rift - through which capitalism's greatest contradiction becomes the irremediable tension between the 'economic equivalence' and the 'natural distinctiveness' of the commodity (Marx) - I illuminate the possibilities for a unified theory of capitalist development and crisis over the longue dure. This is the theory of capitalism as world-ecology, a perspective that joins the accumulation of capital and the production of nature in dialectical unity. This perspective begins from the premise that capitalism does not act upon nature so much as develop through nature-society relations. Capitalism does not have an ecological regime; it is an ecological regime.
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10.
  • Moore, Jason W, 1971- (författare)
  • Wall Street is a way of organizing nature : an interview with Jason W. Moore
  • 2011
  • Ingår i: Upping the Anti: A Journal of Theory and Action. - Toronto : UTA Publications. ; 12
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • My alternative to the Cartesian binary is the world-ecological perspective. This perspective says that the great movements of modern world history – imperialism, transitions in family and gen-der relations, commodification, financial expansions and much more – are messy bundles of human- and extra-human relations. The theory of capitalism as world-ecology builds out from a simple proposition: Just as a farm is a way of organizing nature, so is a market, a financial center, a factory, an empire. The production of nature has been every bit as much about the factories as forests, stock exchanges, shopping centers, slum and suburban sprawls, as it has been about soil exhaustion and species extinction. Focusing on capitalism as world-ecology, I seek a dialectical synthesis of the accumulation of capital, the pursuit of power, and the production of nature. The capitalist world-ecology is a kind of gravitational field. At its vortex is the commodity. The com-modification of everything, capitalism‟s basic tendency, is often considered a social process; in fact it is powerfully ecological. The commodification of everything says that human nature, as labor productivity, is what really counts. Extra-human nature is literally devalued, mobilized in support of rising labor productivity. Capitalism is the gravitational field within which the vast array of “big picture” historical movements of the past five centuries unfolds. Financialization, shifts in family structure, the emergence of new racial orders, colonialism and imperialism, industrialization, social revolutions and workers‟ movements – these are all world-ecological processes and projects, all with powerful visions for re-ordering of human- and extra-human natures.
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