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- Morin, Ruth T., et al.
(författare)
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Depression Severity, but Not Cognitive Impairment or Frailty, is Associated with Disability in Late-Life Depression
- 2020
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Ingår i: Clinical Gerontologist. - : Informa UK Limited. - 0731-7115 .- 1545-2301. ; 43:4, s. 411-419
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Assess the relationship of cognitive impairment to disability, accounting for depression severity and frailty, among older adults with late-life depression (LLD). Methods: Data were analyzed from 78 community-dwelling older adults with LLD and without dementia (age M = 71.9; SD = 6.1). Cognitive functioning was assessed using a comprehensive neuropsychological battery. Depression severity was measured using the 17-item Hamilton Depression Rating Scale (HDRS; cutoff ≥15). Frailty was assessed using several motor tests. The World Health Organization Disability Assessment Schedule (WHO-DAS) measured disability status. A linear regression analysis was performed to identify relationships of cognition, frailty and depression severity with disability. Results: The average number of impaired cognitive tests was 2.0 (SD = 1.9), with 28.2% of participants showing no impaired scores. On average participants reported depression severity of 17.3 (SD = 3.6), and disability total score of 15.1 (SD = 6.9). The regression model accounted for 25.1% of the variance in disability, with only depression severity significantly predicting disability status. Burden of cognitive impairment and frailty were not predictive of disability in this sample. Conclusions: In this sample, only depression severity was associated with increased disability. Clinical Implications: These findings have implications for intervention in LLD, as depression severity may represent a more modifiable risk factor for disability.
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| 2. |
- Morin, Ruth T., et al.
(författare)
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Somatic and anxiety symptoms of depression are associated with disability in late life depression
- 2020
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Ingår i: Aging and Mental Health. - : Informa UK Limited. - 1360-7863 .- 1364-6915. ; 24:8, s. 1225-1228
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To assess the relationships of somatic and anxiety symptoms of depression with functional disability in a sample of older adults with late life depression. Method: Data were analyzed from 78 older adults aged 65–88 with current major depression. Somatic and anxiety symptoms from the 24-item Hamilton Depression Rating Scale (HDRS) were summed to create variables measuring severity of these symptoms. Other symptoms of depression were also assessed using the remaining items of the HDRS. Current physical health burden was assessed using the Functional Comorbidity Index (FCI). Disability was measured with the Late Life Function and Disability Instrument (LLFDI) total limitation score. A linear regression analysis was performed to assess the association of somatic and anxiety symptoms with disability independent of other factors. Results: The model accounted for 26.6% of variance in disability, (F(6,51) = 3.1, p =.01). Somatic (B = −1.9, p =.004) and anxiety (B = −3.7, p =.04) symptoms of depression were significantly associated with disability. Other depressive symptoms and physical illness burden were not associated with disability. Discussion: In older adults with major depression, somatic and anxiety symptoms of depression are associated with disability. Identification and treatment to remission of these symptoms may improve functional outcomes among older depressed adults.
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