| 1. |
- Arbiser, JL, et al.
(författare)
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Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways
- 1997
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424. ; 94:3, s. 861-866
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Tidskriftsartikel (refereegranskat)abstract
- The switch from a quiescent tumor to an invasive tumor is accompanied by the acquisition of angiogenic properties. This phenotypic change likely requires a change in the balance of angiogenic stimulators and angiogenic inhibitors. The nature of the angiogenic switch is not known. Here, we show that introduction of activated H-ras into immortalized endothelial cells is capable of activating the angiogenic switch. Angiogenic switching is accompanied by up-regulation of vascular endothelial growth factor and matrix metalloproteinase (MMP) bioactivity and down-regulation of tissue inhibitor of MMP. Furthermore, we show that inhibition of phosphatidylinositol-3-kinase leads to partial inhibition of tumor angiogenesis, thus demonstrating that activated H-ras activates tumor angiogenesis through two distinct pathways. Finally, we show evidence for two forms of tumor dormancy.
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| 2. |
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| 3. |
- Cedervall, M, et al.
(författare)
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Efficient maximum likelihood DOA estimation for signals with known waveforms in the presence of multipath
- 1997
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Ingår i: IEEE TRANSACTIONS ON SIGNAL PROCESSING. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. ; 45:3
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- We present a large-sample maximum likelihood (ML) algorithm for estimating the directions of arrival (DOA's) and signal amplitudes of known, possibly coherent signals impinging on an array of sensors, The algorithm is an extension of the DEML method of Li
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| 4. |
- Cedervall, M, et al.
(författare)
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Mode-type algorithm for estimating damped, undamped, or explosive modes
- 1997
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Ingår i: CIRCUITS SYSTEMS AND SIGNAL PROCESSING. - : BIRKHAUSER BOSTON INC. - 0278-081X. ; 16:3, s. 349-362
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- We propose a new algorithm for estimating the parameters of damped, undamped, or explosive sinusoidal signals. The algorithm resembles the MODE algorithm, which is commonly used for direction of arrival estimation in the array signal processing held. It i
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| 5. |
- Stoica, P, et al.
(författare)
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Maximum likelihood array processing for stochastic coherent sources
- 1996
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Ingår i: IEEE TRANSACTIONS ON SIGNAL PROCESSING. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 1053-587X. ; 44:1, s. 96-105
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Maximum likelihood (ML) estimation in array signal processing for the stochastic noncoherent signal case is well documented in the literature, Herein, we focus on the equally relevant case of stochastic coherent signals, Explicit large-sample realizations
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