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Investigation of Fo...
Investigation of Four Clusters of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in Rwanda, 2020
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Nsekuye, O (author)
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Rwagasore, E (author)
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Muhimpundu, MA (author)
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- El-Khatib, Z (author)
- Karolinska Institutet
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Ntabanganyimana, D (author)
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Kamayirese, EN (author)
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Ruyange, L (author)
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Umutoni, A (author)
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Adeline, AK (author)
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Ntaganira, J (author)
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Nsazimana, S (author)
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Omolo, J (author)
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(creator_code:org_t)
- 2021-06-30
- 2021
- English.
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In: International journal of environmental research and public health. - : MDPI AG. - 1660-4601. ; 18:13
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https://www.mdpi.com...
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http://kipublication...
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https://doi.org/10.3...
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Abstract
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- We reported the findings of the first Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) four clusters identified in Rwanda. Case-investigations included contact elicitation, testing, and isolation/quarantine of confirmed cases. Socio-demographic and clinical data on cases and contacts were collected. A confirmed case was a person with laboratory confirmation of SARS-CoV-2 infection (PCR) while a contact was any person who had contact with a SARS-CoV-2 confirmed case within 72 h prior, to 14 days after symptom onset; or 14 days before collection of the laboratory-positive sample for asymptomatic cases. High risk contacts were those who had come into unprotected face-to-face contact or had been in a closed environment with a SARS-CoV-2 case for >15 min. Forty cases were reported from four clusters by 22 April 2020, accounting for 61% of locally transmitted cases within six weeks. Clusters A, B, C and D were associated with two nightclubs, one house party, and different families or households living in the same compound (multi-family dwelling). Thirty-six of the 1035 contacts tested were positive (secondary attack rate: 3.5%). Positivity rates were highest among the high-risk contacts compared to low-risk contacts (10% vs. 2.2%). Index cases in three of the clusters were imported through international travelling. Fifteen of the 40 cases (38%) were asymptomatic while 13/25 (52%) and 8/25 (32%) of symptomatic cases had a cough and fever respectively. Gatherings in closed spaces were the main early drivers of transmission. Systematic case-investigations contact tracing and testing likely contributed to the early containment of SARS-CoV-2 in Rwanda.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
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Nsekuye, O
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Rwagasore, E
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Muhimpundu, MA
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El-Khatib, Z
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Ntabanganyimana, ...
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Kamayirese, EN
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show more...
-
Ruyange, L
-
Umutoni, A
-
Adeline, AK
-
Ntaganira, J
-
Nsazimana, S
-
Omolo, J
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show less...
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MEDICAL AND HEAL ...
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Karolinska Institutet