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Course of disease i...
Course of disease in patients with microscopic colitis : a European prospective incident cohort study
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- Verhaegh, Bas P. M. (författare)
- Division of Gastroenterology-Hepatology, Maastricht University Medical Center, Maastricht, the Netherlands,Maastricht Univ, Netherlands
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- Münch, Andreas (författare)
- Linköpings universitet,Avdelningen för molekylär medicin och virologi,Medicinska fakulteten,Region Östergötland, Mag- tarmmedicinska kliniken
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- Guagnozzi, Danila (författare)
- Neuro-Immuno-Gastroenterology Group, Digestive Physiology and Pathophysiology Unit, Vall d'Hebron Research Institute; Digestive System Department, Vall d'Hebron University Hostpital, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain,Vall d'Hebron Univ Hosp, Spain; Vall d'Hebron Univ Hosp, Spain; Ctr Invest Biomed Red Enfermedades Hepat & Digest, Spain
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- Wildt, Signe (författare)
- Department of Gastroenterology, Zealand University Hospital, Køge, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark,Zealand Univ Hosp, Denmark; Univ Copenhagen, Denmark
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- Cebula, W. (författare)
- Division of Gastroenterology, Department of Medicine, Nykoebing Falster Hospital, Nykoebing Falster, Denmark,Nykoebing Falster Hosp, Denmark
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- Diac, A. R. (författare)
- Division of Gastroenterology, Department of Medicine, Nykoebing Falster Hospital, Nykoebing Falster, Denmark,Nykoebing Falster Hosp, Denmark
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- Fernández-Bañares, Fernando (författare)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain; Department of Gastroenterology, Hospital Universitari Mutua Terrassa, Terrassa, Spain,Ctr Invest Biomed Red Enfermedades Hepat & Digest, Spain; Hosp Univ Mutua Terrassa, Spain
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- Al-Khalaf, M. A. R. (författare)
- Division of Gastroenterology, Department of Medicine, Holbaek Hospital, Holbaek, Denmark,Holbaek Cent Hosp, Denmark
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- Pedersen, N. (författare)
- Department of Gastroenterology, Slagelse Hospital, Slagelse, Denmark,Slagelse Hosp, Denmark
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- Kupcinskas, Juozas (författare)
- Department of Gastroenterology and Institute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania,Lithuanian Univ Health Sci, Lithuania; Lithuanian Univ Health Sci, Lithuania
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- Bohr, Johan, 1957- (författare)
- Örebro universitet,Institutionen för hälsovetenskaper,Region Örebro län,Division of Gastroenterology,Örebro Univ, Sweden
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- Macaigne, Gilles (författare)
- Hepatogastroenterology Unit, Centre Hospitalier de Marne-la-Vallee, France,Ctr Hosp Marne Vallee, France
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- Lucendo, Alfredo J. (författare)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain; Department of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Spain; Instituto de Investigación Sanitaria La Princesa, Madrid, Spain,Ctr Invest Biomed Red Enfermedades Hepat & Digest, Spain; Hosp Gen Tomelloso, Spain; Inst Invest Sanitaria La Princesa, Spain
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- Lyutakov, Ivan (författare)
- Department of Gastroenterology, Medical University of Sofia, University Hospital Tsaritsa Yoanna- ISUL, Sofia, Bulgaria,Med Univ Sofia, Bulgaria
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- Tontini, Gian-Eugenio (författare)
- Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Gastroenterology and Endoscopy Unit, Department of Pathophysiology and Transplantation, University of Milan, Italy
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- Pigò, Flavia (författare)
- Gastroenterologia ed Endoscopia Digestiva, Ospedale Civile di Baggiovara, Modena, Italy,Osped Civile Baggiovara, Italy
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- Russo, E. (författare)
- Department of Gastroenterology, Imperial College Healthcare NHS Trust, London, United Kingdom,Imperial Coll Healthcare NHS Trust, England
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- Hjortswang, Henrik (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Mag- tarmmedicinska kliniken
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- Miehlke, Stephan (författare)
- Center for Digestive Diseases, Internal Medicine Center Eppendorf, Hamburg, Germany; Center for Esophageal Disorders, University Hospital Eppendorf, Hamburg, Germany,Internal Med Ctr Eppendorf, Germany; Univ Hosp Eppendorf, Germany
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- Munck, Lars K. (författare)
- Department of Gastroenterology, Zealand University Hospital, Køge, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark,Zealand Univ Hosp, Denmark; Univ Copenhagen, Denmark
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(creator_code:org_t)
- 2021-01-12
- 2021
- Engelska.
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Ingår i: Journal of Crohn's & Colitis. - : Oxford University Press. - 1873-9946 .- 1876-4479. ; 15:7, s. 1174-1183
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- BACKGROUND AND AIMS: The disease course of microscopic colitis (MC) is considered chronic but benign. However, this assumption is based on mainly retrospective studies, reporting on incomplete follow-up of selective cohorts. Systematic, prospective and unbiased data to inform patients and health care professionals on the expected course of the disease and real-life response to therapy are warranted.METHODS: A prospective, pan-European, multi-center, web-based registry was established. Incident cases of MC were included. Data on patient characteristics, symptoms, treatment and quality of life were systematically registered at baseline and during real-time follow-up. Four disease course phenotypes were discriminated and described.RESULTS: Among 381 cases with complete 1-year follow-up, 49% had a chronic active or relapsing disease course, 40% achieved sustained remission after treatment and 11% had a quiescent course. In general, symptoms and quality of life improved after 3 months of follow-up. A relapsing or chronic active disease course was associated with significantly more symptoms and impaired quality of life after 1 year.CONCLUSIONS: A minority of MC patients follow a quiescent disease course with spontaneous clinical improvement, whereas the majority suffers a chronic active or relapsing disease course during the first year after diagnosis, with persisting symptoms accompanied by a significantly impaired quality of life.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Nyckelord
- Microscopic colitis
- disease activity
- disease course
- prognosis
- prospective cohort study
- treatment
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Verhaegh, Bas P. ...
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Münch, Andreas
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Guagnozzi, Danil ...
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Wildt, Signe
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Cebula, W.
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Diac, A. R.
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visa fler...
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Fernández-Bañare ...
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Al-Khalaf, M. A. ...
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Pedersen, N.
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Kupcinskas, Juoz ...
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Bohr, Johan, 195 ...
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Macaigne, Gilles
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Lucendo, Alfredo ...
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Lyutakov, Ivan
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Tontini, Gian-Eu ...
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Pigò, Flavia
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Russo, E.
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Hjortswang, Henr ...
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Miehlke, Stephan
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Munck, Lars K.
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Gastroenterologi
- Artiklar i publikationen
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Journal of Crohn ...
- Av lärosätet
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Örebro universitet
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Linköpings universitet