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- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 3. |
- Khatri, C, et al.
(författare)
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Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study
- 2021
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Ingår i: BMJ open. - : BMJ. - 2044-6055. ; 11:11, s. e050830-
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Tidskriftsartikel (refereegranskat)abstract
- Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis.SettingProspective, international, multicentre, observational cohort study.ParticipantsPatients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative).Primary outcome30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality.ResultsThis study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p<0.001), age >80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787).ConclusionsPatients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups.Trial registration numberNCT04323644
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| 5. |
- Quino Lima, Israel, Doctoral student, 1980-, et al.
(författare)
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Hydrogeochemical contrasts in the shallow aquifer systems of the Lower Katari Basin and Southern Poopó Basin, Bolivian Altiplano
- 2021
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Ingår i: Journal of South American Earth Sciences. - : Elsevier BV. - 0895-9811 .- 1873-0647. ; 105
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Tidskriftsartikel (refereegranskat)abstract
- Drinking water sources in the southeastern part of Lake Titicaca (Lower Katari Basin: LKB) and the southern part of Lake Poopó (Southern Poopó Basin: SPB) have high concentrations of arsenic (As), >10 μg/L compared to the WHO and NB-512 guideline value. These regions belong to the Bolivian Altiplano and are characterized by a semiarid climate, slow hydrological flow, with geological formations of volcanic origin, in addition to brines and other mineral deposits. The present study is focused on comparing the geochemical processes of As in relation to the sources and mobilization in groundwater (GW) in LKB and SPB. Groundwater (GW), surface water (SW) and sediment samples were collected from both basins. The As (LKB: 0.8–288 μg/L and SPB: 2.6–207 μg/L), boron (B) (LKB: 96–2473 μg/L and SPB: 507–4359 μg/L), manganese (Mn) (LKB: 0.6–7259 μg/L) and salinity (LKB: 125–11740 μS/cm) were found to be higher than the WHO guideline values, which is a serious concern about the GW quality for human consumption. The dissolution and exchange of bases are the processes that govern the mineralization of GW. Load of solids and liquids of anthropogenic origin in surface water (LKB) represents an environmental problem for communities on river banks. The spatial distribution of As was attributed to the geology of both the basins and the heterogeneously distributed evaporites in the sediments. The highest As concentrations are found in alluvial sediments of the northern region of LKB and “PACK belt” (an approximately 25 km long belt stretching along the southern shores of the Lake Poopó, between the villages of Pampa Aullagas and Condo K) in SPB. Sequential extraction of sediment and mineral saturation indices indicate that iron (Fe) and aluminum (Al) oxides as well as hydroxides are the most predominant mineral phases as potential sorbents of As.
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