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Träfflista för sökning "WFRF:(Myrtennäs Kerstin) srt2:(2014)"

Sökning: WFRF:(Myrtennäs Kerstin) > (2014)

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1.
  • Birdsell, Dawn N, et al. (författare)
  • Francisella tularensis subsp. tularensis group A.I, United States
  • 2014
  • Ingår i: Emerging Infectious Diseases. - : Centers for Disease Control and Prevention (CDC). - 1080-6040 .- 1080-6059. ; 20:5, s. 861-865
  • Tidskriftsartikel (refereegranskat)abstract
    • We used whole-genome analysis and subsequent characterization of geographically diverse strains using new genetic signatures to identify distinct subgroups within Francisella tularensis subsp. tularensis group A.I: A.I.3, A.I.8, and A.I.12. These subgroups exhibit complex phylogeographic patterns within North America. The widest distribution was observed for A.I.12, which suggests an adaptive advantage.
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2.
  • Lärkeryd, Adrian, et al. (författare)
  • CanSNPer : a hierarchical genotype classifier of clonal pathogens
  • 2014
  • Ingår i: Bioinformatics. - : Oxford University Press. - 1367-4803 .- 1367-4811. ; 30:12, s. 1762-1764
  • Tidskriftsartikel (refereegranskat)abstract
    • Advances in typing methodologies have recently reformed the field of molecular epidemiology of pathogens. The falling cost of sequencing technologies is creating a deluge of whole genome sequencing data that burdens bioinformatics resources and tool development. In particular, single nucleotide polymorphisms in core genomes of pathogens are recognized as the most important markers for inferring genetic relationships because they are evolutionarily stable and amenable to high-throughput detection methods. Sequence data will provide an excellent opportunity to extend our understanding of infectious disease when the challenge of extracting knowledge from available sequence resources is met. Here, we present an efficient and user-friendly genotype classification pipeline, CanSNPer, based on an easily expandable database of predefined canonical single nucleotide polymorphisms.
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