| 1. |
- Enders, J, et al.
(författare)
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Spectral statistics and the fine structure of the electric pygmy dipole resonance in N=82 nuclei
- 2004
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Ingår i: Nuclear Physics, Section A. - : Elsevier BV. - 0375-9474. ; 741, s. 3-28
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Tidskriftsartikel (refereegranskat)abstract
- We study the statistical properties of the electric pygmy dipole resonance in four different isotones with neutron number N = 82. These nuclei are Ba-138(56), Ce-140(58), Nd-142(60), (144)(62)sm. The data set comprises levels with spin and parity J(pi) = 1(-) and their ground state B(E1) transition strengths. The statistics are found to be "mixed", i.e., in between the predictions of random matrix theory for correlated and uncorrelated spectra. Moreover, we calculate spectra and transition strengths in the quasiparticle phonon model (QPM). We compare experimental and theoretical findings. The incompleteness of the data sets and its impact on the results is discussed. A consistent picture emerges which yields an improved understanding of the statistical properties of the pygmy resonance. (
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| 2. |
- Montalescot, G, et al.
(författare)
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Recommendations on percutaneous coronary intervention for the reperfusion of acute ST elevation myocardial infarction.
- 2004
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Ingår i: Heart (British Cardiac Society). - 1468-201X. ; 90:6
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Forskningsöversikt (refereegranskat)abstract
- Little information is currently available from the various societies of cardiology on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI). Since primary PCI is the main method of reperfusion in AMI in many centres, and since of all cardiac emergencies AMI represents the most urgent situation for PCI, recommendations based on scientific evidence and expert experience would be useful for centres practising primary PCI, or those looking to establish a primary PCI programme. To this aim, a task force for primary PCI in AMI was formed to develop a set of recommendations to complement and assist clinical judgment. This paper represents the product of their recommendations.
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| 3. |
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| 4. |
- Berg, Ingrid, et al.
(författare)
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Two modes of germline instability at human minisatellite MS1 (locus D1S7) : complex rearrangements and paradoxical hyperdeletion.
- 2003
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Ingår i: Am J Hum Genet. - 0002-9297. ; 72:6, s. 1436-47
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Tidskriftsartikel (refereegranskat)abstract
- Minisatellite MS1 (locus D1S7) is one of the most unstable minisatellites identified in humans. It is unusual in having a short repeat unit of 9 bp and in showing somatic instability in colorectal carcinomas, suggesting that mitotic replication or repair errors may contribute to repeat-DNA mutation. We have therefore used single-molecule polymerase chain reaction to characterize mutation events in sperm and somatic DNA. As with other minisatellites, high levels of instability are seen only in the germline and generate two distinct classes of structural change. The first involves large and frequently complex rearrangements that most likely arise by recombinational processes, as is seen at other minisatellites. The second pathway generates primarily, if not exclusively, single-repeat changes restricted to sequence-homogeneous regions of alleles. Their frequency is dependent on the length of uninterrupted repeats, with evidence of a hyperinstability threshold similar in length to that observed at triplet-repeat loci showing expansions driven by dynamic mutation. In contrast to triplet loci, however, the single-repeat changes at MS1 exclusively involve repeat deletion, and can be so frequent--as many as 0.7-1.3 mutation events per sperm cell for the longest homogeneous arrays--that alleles harboring these long arrays must be extremely ephemeral in human populations. The apparently impossible existence of alleles with deletion-prone uninterrupted repeats therefore presents a paradox with no obvious explanation.
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| 5. |
- Fritzell, Peter, et al.
(författare)
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Cost-effectiveness of lumbar fusion and nonsurgical treatment for chronic low back pain in the Swedish lumbar spine study : A multicenter, randomized, controlled trial from the Swedish Lumbar Spine Study Group
- 2004
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Ingår i: Spine. - : Lippincott Williams & Wilkins. - 0362-2436 .- 1528-1159. ; 29:4, s. 421-434
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Tidskriftsartikel (refereegranskat)abstract
- Study Design. A cost-effectiveness study was performed from the societal and health care perspectives. Objective. To evaluate the costs-effectiveness of lumbar fusion for chronic low back pain (CLBP) during a 2-year follow-up. Summary of Background Data. A full economic evaluation comparing costs related to treatment effects in patients with CLBP is lacking. Patients and Methods. A total of 284 of 294 patients with CLBP for at least 2 years were randomized to either lumbar fusion or a nonsurgical control group. Costs for the health care sector ( direct costs), and costs associated with production losses ( indirect costs) were calculated. Societal total costs were identified as the sum of direct and indirect costs. Treatment effects were measured using patient global assessment of improvement, back pain ( VAS), functional disability (Owestry), and return to work. Results. The societal total cost per patient ( standard deviations) in the surgical group was significantly higher than in the nonsurgical group: Swedish kroner (SEK) 704,000 ( 254,000) vs. SEK 636,000 ( 208,000). The cost per patient for the health care sector was significantly higher for the surgical group, SEK 123,000 ( 60,100) vs. 65,200 ( 38,400) for the control group. All treatment effects were significantly better after surgery. The incremental cost-effectiveness ratio ( ICER), illustrating the extra cost per extra effect unit gained by using fusion instead of nonsurgical treatment, were for improvement: SEK 2,600 ( 600 - 5,900), for back pain: SEK 5,200 ( 1,100 - 11,500), for Oswestry: SEK 11,300 ( 1,200 - 48,000), and for return to work: SEK 4,100 ( 100 21,400). Conclusion. For both the society and the health care sectors, the 2-year costs for lumbar fusion was significantly higher compared with nonsurgical treatment but all treatment effects were significantly in favor of surgery. The probability of lumbar fusion being cost-effective increased with the value put on extra effect units gained by using surgery.
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| 6. |
- Galakhov, AV, et al.
(författare)
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Influence of the Coulomb parameter U on partial densities of states of CuGeO3: Comparison with X-ray spectral data
- 2004
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Ingår i: European Physical Journal B. Condensed Matter and Complex Systems. - : Springer Science and Business Media LLC. - 1434-6028. ; 41:3, s. 295-300
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Tidskriftsartikel (refereegranskat)abstract
- The electronic structure of the strongly Coulomb correlated cuprate CuGeO3 has been calculated by the local-density-approximation method (LDA+U). The parameter U was varied from 0 to 8 eV. The results of the band-structure calculations are compared with experimental data obtained by means of X-ray photoelectron and resonant X-ray emission spectroscopy methods (Cu Lalpha and O Kalpha X-ray emission spectra). It is established that a LDA+U calculation with U = 4 eV reproduces well the X-ray photoelectron and X-ray resonant emission spectral data.
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| 7. |
- Galakhov, VR, et al.
(författare)
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Co 3d-level position in ZnS : Co semiconductors
- 2003
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Ingår i: Physical Review B (Condensed Matter and Materials Physics). - 1098-0121. ; 68:3: 033204
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Tidskriftsartikel (refereegranskat)abstract
- Experimental studies of x-ray photoelectron and Co Lalpha x-ray emission spectra of the ZnS:Co semiconductor were carried out. It was established that Co ions are present in isovalent Co2+ configuration and that the Co 3d impurity states are localized above the top of the valence band by 1.0 +/- 0.2 eV.
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| 8. |
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| 9. |
- Magnuson, Martin, 1965-, et al.
(författare)
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Magnetic circular dichroism in X-ray fluorescence of Heuseler alloys at threshold excitation
- 2001
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Ingår i: Solid State Communications. - 0038-1098 .- 1879-2766. ; 117:2, s. 79-82
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Tidskriftsartikel (refereegranskat)abstract
- The results of fluorescence measurements of magnetic circular dichroism (MCD) in Mn L2,3 X-ray emission and absorption for Heusler alloys NiMnSb and Co2MnSb are presented. Very intense resonance Mn L3 emission is found at the Mn 2p3/2 threshold and attributed to a peculiarity of the threshold excitation in materials with a half-metallic character of the electronic structure. The excitation energy dependence of Mn L2,3 X-ray emission spectra (XES) was measured at beamline ID12B at the European Synchrotron Radiation Facility (ESRF, Grenoble) using 83% circularly polarized X-rays. A very large MCD effect found in XES is attributed to strong exchange splitting of spin-up and spin-down Mn 3d states. The anomalously high ratio of L2 emission intensity to L3 emission intensity is found.
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| 10. |
- Neumann Andersen, Grethe, et al.
(författare)
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MC(1) receptors are constitutively expressed on leucocyte subpopulations with antigen presenting and cytotoxic functions.
- 2001
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Ingår i: Clinical and Experimental Immunology. - 0009-9104 .- 1365-2249. ; 126:3, s. 441-6
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Tidskriftsartikel (refereegranskat)abstract
- The expression of melanocortin MC(1) receptors on human peripheral lymphocyte subsets was analysed by flow cytometry using rabbit antibodies selective for the human MC(1) receptor and a panel of monoclonal antibodies against lymphocyte differentiation markers. The MC(1) receptor was found to be constitutively expressed on monocytes/macrophages, B-lymphocytes, natural killer (NK) cells and a subset of cytotoxic T-cells. Interestingly T-helper cells appeared to be essentially devoid of MC(1) receptors. The results were confirmed by RT-PCR which indicated strong expression of MC(1) receptor mRNA in CD14(+), CD19(+) and CD56(+) cells. However, only a faint RT-PCR signal was seen in CD3(+) cells, in line with the immuno-staining results that indicated that only part of the CD3(+) cells (i.e. some of the CD8(+) cells) expressed the MC(1) receptor. The MC(1) receptors' constitutive expression on immune cells with antigen-presenting and cytotoxic functions implies important roles for the melanocortic system in the modulation of immune responses.
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