| 1. |
- Dunham, I, et al.
(författare)
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The DNA sequence of human chromosome 22
- 1999
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 402:6761, s. 489-495
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Tidskriftsartikel (refereegranskat)
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| 2. |
- Hansen, G, et al.
(författare)
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Retningslinjer for utredning og behandling av kronisk obstruktiv lungesykdom
- 1995
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Ingår i: Tidsskrift for Den Norske Lægeforening. - 0029-2001. ; 115:6, s. 710-713
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Tidskriftsartikel (refereegranskat)abstract
- A group of chest physicians, general practitioners, clinical pharmacologist and pharmacists appointed by the Institute of Pharmacotherapy, University of Oslo has evaluated the present knowledge about treatment of chronic obstructive lung disease. The group discusses today's medical treatment of this rather numerous group of patients. It is stated that, to a high degree, the treatment of these patients lacks proper documentation, and that treatment needs to be tested out on an individual basis. The group proposes a flow chart for this purpose.
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| 3. |
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| 4. |
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| 5. |
- Johannesson, Magnus, et al.
(författare)
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Willingness to pay for reduced incontinence symptoms
- 1997
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Ingår i: British journal of urology. - : Blackwell. - 1464-410X .- 0007-1331. ; 80:4, s. 557-562
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Tidskriftsartikel (refereegranskat)abstract
- Objective. To measure the willingness to pay for a reduction in the number of micturitions and urinary leakages for patients with urge incontinence. Patients and methods. A self-administered questionnaire with a binary willingness-to-pay question was administered to 541 patients in Sweden with urge or mixed incontinence; 461 questionnaires were returned. The reduction in micturitions and urinary leakages valued in the willingness-to-pay question was varied randomly between 25% and 50% in two different subsamples. Information was also collected about the number of micturitions and urinary leakages, health-related quality of life and socio-economic characteristics of the patients in the study. Results. Quality of life was significantly related to the severity of the symptoms and was worse than that of the sex- and age-matched general Swedish population. The median (mean) willingness to pay per month was 240 (530) Swedish krona (SEK, £1 = SEK 11.50) for a 25% reduction in micturitions and leakages and SEK 470 (1030) for a 50% reduction in micturitions and leakages. As hypothesized, the willingness to pay was significantly related to the size of the reduction in micturitions and leakages, the initial number of micturitions and leakages, and income. Conclusions. Patients with incontinence problems are willing to pay substantial amounts for a reduction in the number of micturitions and leakages.
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| 7. |
- Nguyen, HN, et al.
(författare)
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Abnormal postprandial duodenal chyme transport in patients with long standing insulin dependent diabetes mellitus
- 1997
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Ingår i: Gut. - : BMJ. - 0017-5749 .- 1468-3288. ; 41:5, s. 624-631
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Tidskriftsartikel (refereegranskat)abstract
- AbstractBackground—Patients with long standing diabetes mellitus frequently have upper gut dysmotility. Gastroparesis has been well studied, whereas detailed data on duodenal motor function are limited.Aims—To characterise postprandial duodenal chyme transport in such patients.Methods—Intraluminal multiple impedance measurement, recently introduced as a novel technique for investigation of chyme transport, was used to study postprandial duodenal chyme flow in 10 patients with long standing insulin dependent diabetes mellitus with gastroparesis, and 10 healthy volunteers.Results—Four distinct transport patterns of chyme, termed bolus transport events (BTEs), were found in both groups and could be characterised as: short distance propulsive; simple long distance propulsive; retrograde; and complex long distance propulsive. Diabetic patients had significantly lower numbers of propulsive BTEs (p<0.01), and higher proportions of retrograde BTEs and complex long distance BTEs (p<0.05) than control subjects, whereas the proportion of simple long distance BTEs was significantly lower (p<0.05). The mean propagation velocities of the BTEs were similar in both groups.Conclusion—Abnormal postprandial duodenal chyme transport was found in patients with long standing insulin dependent diabetes mellitus. This is characterised by transport disorganisation and may result in disturbed chyme clearance.
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