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- Falk-Brynhildsen, Karin, 1959-, et al.
(författare)
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Bacterial colonization of the skin following aseptic preoperative preparation and impact of the use of plastic adhesive drapes
- 2013
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Ingår i: Biological Research for Nursing. - : SAGE Publications. - 1099-8004 .- 1552-4175. ; 15:2, s. 242-248
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Tidskriftsartikel (refereegranskat)abstract
- Surgical site contamination, for example, with coagulase-negative staphylococci, probably derives from both the patient’s own skin flora and those of the surgical team. Despite preoperative antiseptic preparation with chlorhexidine solution, complete sterilization of the skin is not possible and gradual recolonization will occur. Plastic adhesive drape is an established method used to prevent direct wound contamination from adjacent skin. In this study, the time to skin recolonization after antiseptic preparation was measured and the impact of using plastic adhesive drape on this recolonization was evaluated. Repeated bacterial sampling using three different methods over 6 hr was conducted after antiseptic preparation in 10 volunteers. Recolonization of skin was observed after 30 min with plastic drape and after 60 min without plastic drape; there were significantly more positive cultures with the plastic drape than without (31% vs. 7.5%, respectively, p < .001). Sampling with a rayon swab was the most sensitive sampling method. In conclusion, covering the skin with a plastic adhesive drape seems to hasten recolonization of the skin after antiseptic preparation. However, clinical trials to confirm this finding are warranted.
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| 3. |
- Falk-Brynhildsen, Karin, 1959-, et al.
(författare)
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Bacterial growth and wound infection following saphenous vein harvesting in cardiac surgery : a randomized controlled trial of the impact of microbial sealant
- 2014
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Ingår i: European Journal of Clinical Microbiology and Infectious Diseases. - : Springer. - 0934-9723 .- 1435-4373. ; 33:11, s. 1981-1987
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Tidskriftsartikel (refereegranskat)abstract
- The aim of the present study was to compare microbial skin sealant versus bare skin on the leg regarding intraoperative bacterial presence in the surgical wound and time to recolonization of the adjacent skin at the saphenous vein harvesting site. A second aim was to evaluate the incidence of leg wound infection 2 months after surgery. In this randomized controlled trial, 140 patients undergoing coronary artery bypass grafting (CABG) between May 2010 and October 2011 were enrolled. Bacterial samples were taken preoperatively and intraoperatively at multiple time points and locations. OF the patients, 125 (92.6 %) were followed up 2 months postoperatively regarding wound infection. Intraoperative bacterial growth did not differ between the bare skin (n = 68) and the microbial skin sealant group (n = 67) at any time point. At 2 months postoperatively, 7/61 patients (11.5 %) in the skin sealant versus 14/64 (21.9 %) in the bare skin group (p = 0.120) had been treated with antibiotics for a verified or suspected surgical site infection (SSI) at the harvest site. We found almost no intraoperative bacterial presence on the skin or in the subcutaneous tissue, irrespective of microbial skin sealant use. In contrast, we observed a relatively high incidence of late wound infection, indicating that wound contamination occurred postoperatively. Further research is necessary to determine whether the use of microbial skin sealant reduces the incidence of leg wound infection at the saphenous vein harvest site.
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| 4. |
- Falk-Brynhildsen, Karin, 1959-, et al.
(författare)
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Bacterial recolonization of the skin and wound contamination during cardiac surgery : a randomized controlled trial of the use of plastic adhesive drape compared with bare skin
- 2013
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Ingår i: Journal of Hospital Infection. - London, United Kingdom : Saunders Elsevier. - 0195-6701 .- 1532-2939. ; 84:2, s. 151-158
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Tidskriftsartikel (refereegranskat)abstract
- Background: Sternal wound infection after cardiac surgery is a serious complication. Various perioperative strategies, including plastic adhesive drapes, are used to reduce bacterial contamination of surgical wounds.Aim: To compare plastic adhesive drape to bare skin regarding bacterial growth in wound and time to recolonization of the adjacent skin intraoperatively, in cardiac surgery patients.Methods: This single-blinded randomized controlled trial (May 2010 to May 2011) included 140 patients scheduled for cardiac surgery via median sternotomy. The patients were randomly allocated to the adhesive drape (chest covered with plastic adhesive drape) or bare skin group. Bacterial samples were taken preoperatively and intraoperatively every hour during surgery until skin closure.Results: Disinfection with 0.5% chlorhexidine solution in 70% alcohol decreased coagulase-negative staphylococci (CoNS), while the proportion colonized with Propionibacterium acnes was not significantly reduced and was still present in more than 50% of skin samples. P. acnes was significantly more common in men than in women. Progressive bacterial recolonization of the skin occurred within 2-3 h. At 120 min there were significantly more positive cultures in the adhesive drape group versus bare skin group for P. acnes (63% vs 44%; P = 0.034) and for CoNS (45% vs 24%; P = 0.013). The only statistically significant difference in bacterial growth in the surgical wound was higher proportion of CoNS at the end of surgery in the adhesive drape group (14.7% vs 4.4%; P = 0.044).Conclusion: Plastic adhesive drape does not reduce bacterial recolonization. P. acnes colonized men more frequently, and was not decreased by disinfection with chlorhexidine solution in alcohol.
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| 6. |
- Falk-Brynhildsen, Karin, 1959-
(författare)
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The effect of peroperative skin preparation on bacterial growth during cardiac surgery
- 2013
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Routine products are used and procedures are followed in order to prevent and minimize the bacterial contamination of the surgical wound, and thus reduce the risk of postoperative wound infections. The overall aim of this thesis was to investigate the effect of different preoperative skin preparation before cardiac surgery.In study I, 10 healthy volunteers were compared in time to recolonization of the skin and bacterial growth with or without plastic adhesive drape. Bacterial samples were taken as paired samples on both side of the sternum. Plastic drape on disinfected skin seems to hasten recolonization compared with bare skin.In study II, 135 cardiac surgery patients were comparing plastic adhesive drape versus bare skin on the chest regarding intra-operative bacterial growth. Plastic adhesive drape did not reduce the bacterial recolonization or wound contamination, P. acnes colonizes males more often than females and P. acnes is not affected by disinfection with 0.5% chlorhexidine in ethanol.Study III, compared the leg harvesting site with or without microbal skin sealant in 135 CABG patients regarding intraoperative bacterial growth and postoperative wound infection. Almost no bacterial growth was found during surgery regardless of the use of microbial skin sealant and bare skin. A high incidence of postoperative wound infections (16.8%) in 2 month follow up was present and SSI was largely caused by S. aureus, i.e. other bacterial species than observed intraoperative.Study IV, a descriptive study using phenotypic and genotypic methods investigate susceptibility to chlorhexidine among S. epidermidis indicating that S. epidermidis isolates following preoperative skin disinfection are sensitive tochlorhexidine.
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Fint språk = Good Language : festskrift till Lars-Gunnar Andersson
- 2014. - 1
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Samlingsverk (redaktörskap) (refereegranskat)abstract
- Festskrift till Lars-Gunnar Andersson med anledning av hans 65-årsdag. Boken innehåller 20 artiklar om språk av följande författare: Karin Aijmer, Sture Allén, Gunnar Bergh & Sölve Ohlander, Elisabet Engdahl, Catharina Grünbaum, Olle Josephson, Fred Karlsson, Lars Lindvall & Mårten Ramnäs, Per Linell & Kerstin Norén, Magnus Ljung, Sven-Göran Malmgren, Bengt Nordberg, Christer Platzack, Bo Ralph, Lena Rogström, Eva Sundgren, Ulf Teleman, Mats Thelander & Björn Melander, Peter Trudgill samt Jan-Ola Östman.
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| 8. |
- Lundgren, Anna Sofia, 1972-, et al.
(författare)
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Inledning
- 2012
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Ingår i: Mitt i metoden. - Umeå : Institutionen för kultur- och medievetenskaper, Umeå universitet. - 9789174595093 ; , s. 7-16
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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