| 1. |
- Garkavij, Martin, et al.
(författare)
-
Extracorporeal whole-blood immunoadsorption enhances radioimmunotargeting of iodine-125-labeled BR96-biotin monoclonal antibody
- 1997
-
Ingår i: Journal of Nuclear Medicine. - 0161-5505. ; 38:6, s. 895-901
-
Tidskriftsartikel (refereegranskat)abstract
- This study investigates the efficacy of tumor radioimmunotargeting with 125I-labeled BR96-biotin monoclonal antibody using a new method, whole-blood immunoadsorption (WBIA), based on direct adsorption of unbound monoclonal antibody (MAb) from blood without preceding separation of plasma. METHODS: Highly tumor-reactive, internalizing, chimeric BR96 MAb of isotype IgG1 binds to a tumor-associated Lewis-type (Le(Y)) cell surface antigen. Forty-six Brown Norwegian male rats were inoculated intramuscularly and beneath the liver or kidney capsule with syngeneic rat colon carcinoma BN7005, expressing Lewis-type antigen, and investigated. The rats were injected intravenously with 3.5-4.5 MBq 125I-labeled BR96-biotin. Twenty of the rats underwent WBIA starting 5 or 12 hr after injection. About six blood volumes were passed through an avidin-gel adsorption column during 2 hr. RESULTS: By using WBIA, whole-body radioactivity was reduced by 50%, and plasma activity by 85%. Both directly after completion of WBIA and 33 hr later, the activity uptake in tumors manifested only a nonsignificant decrease as compared with corresponding controls (p > 0.05) and had approximately similar time-activity curves. Uptake ratios for tumor (T):bone marrow, T:liver, T:kidney and T:lung were enhanced 2.3- to 3.5-fold in all three tumor models, as compared with controls. The ratio of liver tumor to bone marrow was improved from 10:1 to 30:1. CONCLUSION: This new method of WBIA yields significantly improved radioimmunotargeting of highly tumor-reactive, internalizing MAb BR96.
|
|
| 2. |
|
|
| 3. |
|
|
| 4. |
- Adawi, Tom, 1970, et al.
(författare)
-
Goldstone tensor modes
- 1998
-
Ingår i: J. High Energy Phys. 9902:001,1999.
-
Tidskriftsartikel (refereegranskat)abstract
- In the context of brane solutions of supergravity, we discuss a general method to introduce collective modes of any spin by exploiting a particular way of breaking symmetries. The method is applied to the D3, M2 and M5 branes and we derive explicit expressions for how the zero-modes enter the target space fields, verify normalisability in the transverse directions and derive the corresponding field equations on the brane. In particular, the method provides a clear understanding of scalar, spinor, and rank r tensorial Goldstone modes, chiral as well as non-chiral, and how they arise from the gravity, Rarita-Schwinger, and rank r+1 Kalb-Ramond tensor gauge fields, respectively. Some additional observations concerning the chiral tensor modes on the M5 brane are discussed.
|
|
| 5. |
- Adawi, Tom, 1970, et al.
(författare)
-
Superembeddings, nonlinear supersymmetry and five-branes
- 1997
-
Ingår i: Int.J.Mod.Phys.A13:4691-4716,1998.
-
Tidskriftsartikel (refereegranskat)abstract
- We examine general properties of superembeddings, i.e., embeddings of supermanifolds into supermanifolds. The connection between an embedding procedure and the method of non-linearly realised supersymmetry is clarified, and we demonstrate how the latter arises as a special case of the former. As an illustration, the super-5-brane in 7 dimensions, containing a self-dual 3-form world-volume field strength, is formulated in both languages, and provides an example of a model where the embedding condition does not suffice to put the theory on-shell.
|
|
| 6. |
- Aleksandrov, D., et al.
(författare)
-
Invariant mass spectrum and alpha-n correlation function studied in the fragmentation of He-6 on a carbon target
- 1998
-
Ingår i: Nuclear Physics A. - 0375-9474. ; 633:2, s. 234-246
-
Tidskriftsartikel (refereegranskat)abstract
- Momentum distributions and invariant mass spectra from the breakup of He-6 ions with an energy of 240 MeV/u interacting with a carbon target have been studied. The data were used to extract information about the reaction mechanism which is influenced by the structure of He-6. It is found that the dominant reaction mechanism is a two-step process: knock out of one neutron followed by the decay of the He-5 resonance. The shape of the (alpha+n) two-body invariant mass spectrum is interpreted as mainly reflecting the 5He ground state which is a J(pi) = 3/2(-) resonance. However, no evidence for correlations between cu particles and neutrons is observed in the momentum widths of the distributions. It is demonstrated that a combined analysis of the two-body invariant mass spectrum and an appropriate correlation function may be used to determine the properties of the intermediate resonance. (C) 1998 Elsevier Science B.V.
|
|
| 7. |
- Axelsson, L., et al.
(författare)
-
Beta decay of Ar-31
- 1998
-
Ingår i: Nuclear Physics A. - 0375-9474. ; 634:4, s. 475-496
-
Tidskriftsartikel (refereegranskat)abstract
- A complete study of Ar-31 beta decay has been made by high-resolution charged-particle and gamma-ray spectroscopy. Beta-delayed radiation was detected by an array of three charged-particle detectors and a large-volume germanium detector. Fifteen new energy levels were discovered in Cl-31. The beta-strength distribution, measured to 14.5 MeV, is compared with a shell-model calculation in the full sd space. The quenching of the Gamow-Teller strength and the isospin impurity of the IAS in Cl-31 are discussed. (C) 1998 Published by Elsevier Science B.V.
|
|
| 8. |
- Axelsson, L., et al.
(författare)
-
Two-proton emission in the decay of Ar-31
- 1998
-
Ingår i: Nuclear Physics A. - 0375-9474. ; 628:3, s. 345-362
-
Tidskriftsartikel (refereegranskat)abstract
- Several beta-delayed two-proton branches were observed in the decay of Ar-31, the most intense ones proceeding through the isobaric analogue state (IAS) in Cl-31. The mechanism of the two-proton emission is studied via the energy and angular distributions of the two protons, Simultaneous emission of the two protons fits the present data well, sequential decays might also describe them. Independent of the decay mechanism, a spin of 5/2 for the IAS is suggested, An improved limit on the direct two-proton emission fi om the ground state of Ar-31 is presented, (C) 1998 Elsevier Science B.V.
|
|
| 9. |
- Baumann, T., et al.
(författare)
-
Longitudinal momentum distributions of C-16,C-18 fragments after one-neutron removal from C-17,C-19
- 1998
-
Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - 0370-2693. ; 439:3-4, s. 256-261
-
Tidskriftsartikel (refereegranskat)abstract
- The fragment separator FRS at GSI was used as an energy-loss spectrometer to measure the longitudinal momentum distributions of C-16,C-18 fragments after one-neutron removal reactions in C-17,C-19 impinging on a carbon target at about 910 MeV/u. The distributions in the projectile frames are characterized by a FWHM of 141 +/- 6 MeV/c for C-16 and 69 +/- 3 MeV/c for C-18. Th, results are compared with experimental data obtained at lower energies and discussed within existing theoretical models. (C) 1998 Elsevier Science B.V. AU rights reserved.
|
|
| 10. |
- Beckman, Claes, 1962-
(författare)
-
Antenna-to-Antenna Isolation Measurements
- 1999
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- In this document we show results from measurements of the antenna-to-antenna isolation between different types of base station antenna configurations. The measurements are conducted on antennas for the GSM1800 band. However, since this band is relatively close to the IMT-2000 band it is reasonable to assume similar results for antennas to be used in this band.In this report we present measurement results from antennas with both vertical and slanted dual polarisation, and different horizontal beamwidths. The different antennas are shown in Table 1. The isolation is measured with the antennas positioned for some different configurations.
|
|
