| 1. |
- Katayama, S, et al.
(författare)
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Antisense transcription in the mammalian transcriptome
- 2005
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Ingår i: Science (New York, N.Y.). - : American Association for the Advancement of Science (AAAS). - 1095-9203 .- 0036-8075. ; 309:5740, s. 1564-1566
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Tidskriftsartikel (refereegranskat)abstract
- Antisense transcription (transcription from the opposite strand to a protein-coding or sense strand) has been ascribed roles in gene regulation involving degradation of the corresponding sense transcripts (RNA interference), as well as gene silencing at the chromatin level. Global transcriptome analysis provides evidence that a large proportion of the genome can produce transcripts from both strands, and that antisense transcripts commonly link neighboring “genes” in complex loci into chains of linked transcriptional units. Expression profiling reveals frequent concordant regulation of sense/antisense pairs. We present experimental evidence that perturbation of an antisense RNA can alter the expression of sense messenger RNAs, suggesting that antisense transcription contributes to control of transcriptional outputs in mammals.
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| 2. |
- Nishida, Masahiro, et al.
(författare)
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Evaluation of dynamic compressive properties of PLA polymer blends using split Hopkinson pressure bar
- 2009
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Ingår i: DYMAT 2009, 9th International conferense on the mechanical and physical behaviour of materials under dynamic loading. - Les Ulis : EDP Sciences. - 9782759804726 ; , s. 909-915
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Konferensbidrag (refereegranskat)abstract
- Poly(lactic acid) (PLA) has been used as a biomaterial for bone fixation devices in oral and orthopedic surgery because of good biocompatibility and bioabsorbability. Because Poly(e-Caprolactone) (PCL) is a ductile, bioabsorbable and biodegradable polymer, many types of PLA/ PCL polymer blends have been developed to improve its material strength and impact resistance. The stress-strain curves of PLA and PLA/PCL polymer blends were measured using a split Hopkinson pressure bar (Kolsky bar) method and a universal testing machine. The effect of PCL content on Young's modulus and yield stress was examined. The values of constants in Cowper-Symonds equation with respect to yield stress were determined for PLA and PLA/PCL polymer blend specimens. PLA/PCL specimens were observed using a scanning electron microscope.
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| 3. |
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| 4. |
- Nishida, T., et al.
(författare)
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Optical sum-frequency emission from Langmuir-Blodgett films of variable thickness : Effects of the substrate and polar orientation of fatty acids in the films
- 2006
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 96:7
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Tidskriftsartikel (refereegranskat)abstract
- The nonlinear optical response arising from a model multilayer structure, i.e., Langmuir-Blodgett (LB) films comprised of different numbers of per-protonated (H) and per-deuterated (D) fatty acid layers on solid substrates, has been evaluated by sum-frequency generation (SFG) spectroscopy. The SFG signals depend significantly on the absolute polar orientation of the fatty acids in the individual layers and on the nonlinear optical response of the substrate. The SFG spectra on gold and fused quartz substrates demonstrate a totally different dependence on the number of the contributing H layers, which it is possible to analyze quantitatively. The results provide important information for understanding the origin of the nonlinear optical responses from ordered systems composed of multiple interfaces and therefore for extracting exact structural information about each interface from the observed SFG signals.
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