| 1. |
- Agardh, Emilie E, et al.
(author)
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Work stress and low sense of coherence is associated with type 2 diabetes in middle-aged Swedish women.
- 2003
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In: Diabetes Care. - : American Diabetes Association. - 0149-5992 .- 1935-5548. ; 26:3, s. 719-24
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Journal article (peer-reviewed)abstract
- OBJECTIVE: The risk of type 2 diabetes is suggested to be increased for individuals exposed to stress. We analyzed the association of work stress by high demands, low decision latitude, and job strain (combination of high demands and low decision latitude) with type 2 diabetes. We also studied low sense of coherence (SOC) (a factor for successful coping with stressors) in association with type 2 diabetes. Finally, we investigated the combination of SOC and demands or SOC and decision latitude in association with the disease. RESEARCH DESIGN AND METHODS: This cross-sectional study recruited 4821 healthy Swedish women (aged 35-56 years) residing in five municipalities in the Stockholm area. An oral glucose tolerance test identified 52 women with type 2 diabetes. Relative risks (RRs) with 95% CIs were estimated in a logistic multiple regression analysis. RESULTS: No association was found between high demands and type 2 diabetes (RR 1.1 [CI 0.5-2.2]). Low decision latitude was associated with type 2 diabetes with a RR of 2.2 (1.0-4.8). The RR of type 2 diabetes with low SOC was 3.7 (1.2-11.2). The combination of low SOC and low decision latitude was associated with type 2 diabetes with a RR of 2.6 (1.2-5.7). Homeostasis model assessment revealed an association of 4.2 (1.2-15.0) between low SOC and insulin resistance. CONCLUSIONS: This study provided new evidence that stress factors such as low decision latitude at work and low SOC were associated with type 2 diabetes in middle-aged Swedish women.
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| 2. |
- Schafer, Werner, et al.
(author)
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Good urodynamic practices: uroflowmetry, filling cystometry, and pressure-flow studies
- 2002
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In: Neurourology and Urodynamics. - : Wiley. - 0733-2467. ; 21:3, s. 261-274
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Journal article (peer-reviewed)abstract
- This is the first report of the International Continence Society (ICS) on the development of comprehensive guidelines for Good Urodynamic Practice for the measurement, quality control, and documentation of urodynamic investigations in both clinical and research environments. This report focuses on the most common urodynamics examinations; uroflowmetry, pressure recording during filling cystometry, and combined pressure-flow studies. The basic aspects of good urodynamic practice are discussed and a strategy for urodynamic measurement, equipment set-up and configuration, signal testing, plausibility controls, pattern recognition, and artifact correction are proposed. The problems of data analysis are mentioned only when they are relevant in the judgment of data quality. In general, recommendations are made for one specific technique. This does not imply that this technique is the only one possible. Rather, it means that this technique is well-established, and gives good results when used with the suggested standards of good urodynamic practice.
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| 4. |
- Green, Anders, et al.
(author)
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User centered design for intelligent service robots
- 2000
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In: IEEE RO-MAN 2000. - Piscataway : IEEE. - 078036273X ; , s. 161-166, s. 161-166
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Conference paper (peer-reviewed)abstract
- This paper describes the development of a fetch-and-carry robot to assist physically impaired people in an office environment. Different methods involving users are employed in the project, including the task analysis, Hi-Fi simulation trials and focus group sessions. Through an iterative design process, a prototype robot system has been developed, with an enhanced robot platform including a graphical user interface and natural language interface. The users' need for continuous feedback from the robot has led to the development of an animated character (CERO), which relates the two interface components and indicates the robot's current state by using simple gestures
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| 5. |
- Hüttenrauch, Helge, et al.
(author)
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Involving users in the design of a mobile office robot
- 2004
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In: IEEE transactions on systems, man and cybernetics. Part C, Applications and reviews. - : IEEE. - 1094-6977 .- 1558-2442. ; 34:2, s. 113-124
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Journal article (peer-reviewed)abstract
- This paper describes the experiences from the iterative design of a fetch-and-carry-robot, to be used by motion-impaired people in an office environment. A user-centered approach was chosen, involving several steps of information elicitation to inform the design. We describe the main elements of the design process, the communication and interaction components of the final prototype system, and an evaluation of the system in the form of a longitudinal study. Results from this study confirmed that continuous testing with users is extremely important in the design process for service robots. The trials have also revealed that interaction design for robots should not focus only on the individual user, but that other members in the environment can be seen "secondary users" or "bystanders" who tend to relate to the robot actively in various ways. We conclude that these social and collaborative issues should be studied in future research.
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| 8. |
- Sennström, Maria B., et al.
(author)
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Human cervical ripening, an inflammatory process mediated by cytokines
- 2000
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In: Molecular Human Reproduction. - : Oxford University Press (OUP). - 1360-9947 .- 1460-2407. ; 6:4, s. 81-375
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Journal article (peer-reviewed)abstract
- An extensive remodelling process, referred to as cervical ripening, takes place in the cervical tissue during pregnancy and labour. It is recognized as softening and dilation of the cervical canal, and starts as a slow process during pregnancy, becoming rapid close to partum. In this study we focus on cytokines as possible mediators of this final remodelling. mRNA levels for interleukin (IL)-8, IL-6 and granulocyte colony-stimulating factor (G-CSF) were upregulated in the ripe postpartum cervical tissue (n = 8) compared to the unripe state (n = 9). Likewise, released cytokine concentrations increased from non-pregnant (n = 11) to the term-pregnant group (n = 13) with a further increase at partum (n = 16). IL-8 concentrations increased 4-fold from non-pregnant to term-pregnant (P<0.01), and a further 10-fold to postpartum state (P<0.0001). Concentrations of IL-6 and G-CSF were similarly increased. Specific IL-8 immunostaining was identified in the epithelia of pregnant cervical tissue (n = 7) and was most pronounced in the epithelia and stroma of postpartum tissue (n = 4). In conclusion, IL-8, IL-6 and G-CSF increase in the human cervix during the ripening process, indicating their important role in the cervical remodelling. These data demonstrate that cervical ripening is similar to an inflammatory process.
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