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Efficacy, acceptabi...
Efficacy, acceptability and tolerability of the combined contraceptive ring, NuvaRing, compared with an oral contraceptive containing 30 mug of ethinyl estradiol and 3 mg of drospirenone
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Ahrendt, Hans-Joachim (författare)
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Nisand, Israel (författare)
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Bastianelli, C. (författare)
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Gomez, M. A. (författare)
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- Gemzell-Danielsson, K. (författare)
- Karolinska Institutet
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Urdl, W. (författare)
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Karskov, B. (författare)
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Oeyen, L. (författare)
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Bitzer, J. (författare)
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Page, G. (författare)
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- Milsom, Ian, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper,Institute of Clinical Sciences
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(creator_code:org_t)
- Elsevier BV, 2006
- 2006
- Engelska.
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Ingår i: Contraception. - : Elsevier BV. - 0010-7824. ; 74:6, s. 451-457
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
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- PURPOSE: This randomized multicenter, open-label, trial compared efficacy, acceptability, tolerability and compliance of NuvaRing with a combined oral contraceptive (COC), containing 30 mug of ethinyl estradiol (EE) and 3 mg of drospirenone. METHOD: In this 13-cycle study, 983 women were randomized and treated (intent-to-treat population) with NuvaRing or COC. RESULTS: One in-treatment pregnancy occurred with NuvaRing (Pearl Index=0.25) (95% confidence interval [CI]: 0.006, 1.363) and four with the COC (Pearl Index=0.99) (95% CI: 0.269, 2.530). For both groups, compliance (89.2% NuvaRing, 85.5% COC) and satisfaction (84% NuvaRing; 87% COC) were high; the vast majority of women found NuvaRing easy to insert (96%) and remove (97%). Tolerability was similar; the most frequent adverse events with NuvaRing were related to ring use, whereas estrogen-related events were more common with the COC. CONCLUSION: NuvaRing has comparable efficacy and tolerability to a COC containing 30 mug of EE and 3 mg drospirenone. User acceptability of both methods was high.
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Ahrendt, Hans-Jo ...
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Nisand, Israel
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Bastianelli, C.
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Gomez, M. A.
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Gemzell-Danielss ...
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Urdl, W.
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visa fler...
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Karskov, B.
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Oeyen, L.
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Bitzer, J.
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Page, G.
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Milsom, Ian, 195 ...
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visa färre...
- Artiklar i publikationen
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Contraception
- Av lärosätet
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Göteborgs universitet
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Karolinska Institutet