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Operative treatment...
Operative treatment of cervical radiculopathy : anterior cervical decompression and fusion compared with posterior foraminotomy
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- Holy, Marek, 1981- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Orthopedic Surgery
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- MacDowall, Anna (författare)
- Department of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden
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- Sigmundsson, Freyr Gauti, 1972- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Orthopedic Surgery
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- Olerud, Class (författare)
- Department of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden
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(creator_code:org_t)
- 2021-09-08
- 2021
- Engelska.
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Ingår i: Trials. - : BioMed Central. - 1745-6215. ; 22:1
- Relaterad länk:
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https://doi.org/10.1...
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https://trialsjourna...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Cervical radiculopathy is the most common disease in the cervical spine, affecting patients around 50-55 year of age. An operative treatment is common clinical praxis when non-operative treatment fails. The controversy is in the choice of operative treatment, conducting either anterior cervical decompression and fusion or posterior foraminotomy. The study objective is to evaluate short- and long-term outcome of anterior cervical decompression and fusion (ACDF) and posterior foraminotomy (PF)METHODS: A multicenter prospective randomized controlled trial with 1:1 randomization, ACDF vs. PF including 110 patients. The primary aim is to evaluate if PF is non-inferior to ACDF using a non-inferiority design with ACDF as "active control." The neck disability index (NDI) is the primary outcome measure, and duration of follow-up is 2 years.DISCUSSION: Due to absence of high level of evidence, the authors believe that a RCT will improve the evidence for using the different surgical treatments for cervical radiculopathy and strengthen current surgical treatment recommendation.TRIAL REGISTRATION: ClinicalTrials.gov NCT04177849. Registered on November 26, 2019.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
Nyckelord
- Anterior cervical decompression
- Anterior cervical discectomy
- Posterior foraminotomy
- Randomized control trial
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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