| 1. |
- Löfberg, H, et al.
(author)
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Occurrence of gamma-trace in the calcitonin-producing C-cells of simian thyroid gland and human medullary thyroid carcinoma
- 1983
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In: Acta Endocrinologica. - : Oxford University Press (OUP). - 0001-5598 .- 0804-4643 .- 1479-683X. ; 104:1, s. 69-76
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Journal article (peer-reviewed)abstract
- gamma-Trace, a microprotein occurring in neuroendocrine cells, was demonstrated by immunohistochemical technique to be present in the calcitonin-producing C-cells of normal simian thyroid gland and of human medullary thyroid carcinoma. A comparatively high concentration of gamma-trace was demonstrated in tissue extract of neoplastic C-cells. The immunoreactive protein found in the extract had a molecular weight and electrophoretic mobility characteristic for gamma-trace.
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| 2. |
- Alm, P., et al.
(author)
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Immunoglobulin-A producing probably primary lymphoma of the breast
- 1983
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In: Virchows Archiv. - 1432-2307. ; 399:3, s. 355-360
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Journal article (peer-reviewed)abstract
- A breast tumour from a 65-year old woman was found to be a primary non-Hodgkin lymphoma, a very rare primary malignancy in this location. The lymphoma was of a diffuse histiocytic type according to the classification of Rappaport, or polymorphic immunocytoma according to the Kiel classification. Immunohistochemistry, not previously reported for breast lymphomas, revealed the production of IgA. In the serum this appeared as an IgA M-component which was greatly reduced after tumour removal. Immunological properties of primary breast lymphomas are reviewed, we suggest further extended studies with the immunohistochemical use of marker substances for the evaluation of prognosis. © 1983 Springer-Verlag.
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| 3. |
- Brandt, L., et al.
(author)
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Uptake of thymidine in lymphoma cells obtained through fine-needle aspiration biopsy. Relation to prognosis in non-hodgkin's lymphomas
- 1981
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In: European Journal of Cancer and Clinical Oncology. - 0277-5379. ; 17:11, s. 1229-1233
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Journal article (peer-reviewed)abstract
- In vitro uptake of tritiated thymidine was studied in autoradiographic preparations of lymphoma cell suspensions obtained through fine-needle aspiration biopsy from 28 patients with non-Hodgkin's lymphoma. The labelling indices (LI ) were highest in patients with histiocytic or poorly differentiated lymphocytic lymphoma. During a two-year period there was a significant correlation between LI and survival, i.e., high LI were associated with a poor prognosis. The results indicate that, in addition to morphology, estimation of the proliferative activity of lymphoma cells may be of clinical significance. © 1981, Pergamon Press Ltd.. All rights reserved.
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| 4. |
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| 5. |
- Grundevik, P, et al.
(author)
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Hyperfine structure in the 6p5d configuration and isotope shifts in transitions between the 6s5d and the 6p5d configurations in Ba I
- 1982
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In: Zeitschrift für Physik A Hadrons and Nuclei. - 0939-7922. ; 306:3, s. 195-209
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Journal article (peer-reviewed)abstract
- High-resolution laser fluorescence spectroscopy, using a single-mode dye laser acting on a collimated atomic beam, has been performed to determine the hyperfine-structure (hfs) constants in six states of the 6p 5d configuration of135Ba and137Ba. Isotope shifts (IS) for eleven transitions between the 6s 5d and the 6p 5d configurations have also been measured. From an analysis of the energy levels, intermediate angular wavefunctions have been deduced. The wavefunctions are used to evaluate experimental hyperfine parameters from the experimental hfs constants. The parameters are, for the magnetic-dipole interaction compared with theoretical values, and for the electricquadrupole interaction used to estimate the nuclear quadrupole moments for the odd isotopes.
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| 6. |
- Göransson, L., et al.
(author)
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Effects of different handling systems on pig feed quality
- 1982
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In: Animal Feed Science and Technology. - : Elsevier BV. - 0377-8401 .- 1873-2216. ; 7:1, s. 11-26
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Journal article (peer-reviewed)abstract
- Separation of feed mixtures and its effect on the production traits of growing-finishing pigs was studied in three experiments. In Experiments I and II the effects of different types of equipment to prevent separation in a silo were studied. Experiment III dealt with separation along a feed transport chain. Experiments I and II clearly demonstrated an increase in feed quality variation by filling a silo without any arrangement to reduce separation. The last feed to be extracted from a silo filled in this manner showed an increasing amount of small particles and contents of crude fibre and ash, a decrease in the bulk density and also in the digestibility of nutrients and in the performance of the pigs. Filling a silo equipped with chutes by an auger or pneumatically through a cyclone did not create separation problems, and consequently there were no differences between these treatments in the production experiments. Separation measured by particle size, bulk density or chemical composition was not noticeable along the feed transport chain (Experiment III). There was no effect on performance of the pigs of their location along the chain. © 1982.
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| 7. |
- Löfberg, H, et al.
(author)
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gamma-trace in human pituitary adenomas
- 1984
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In: The Journal of clinical endocrinology and metabolism. - : The Endocrine Society. - 0021-972X .- 1945-7197. ; 59:1, s. 8-113
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Journal article (peer-reviewed)abstract
- gamma-Trace, a small protein occurring in body fluids and in secretory and neuroendocrine cells, was demonstrated by immunohistochemical techniques in the cytoplasm of the tumor cells of 13 pituitary adenomas obtained at surgery and autopsy. Seven of the adenomas also contained LH immunoreactivity. FSH, TSH, and ACTH were each found in one gamma-trace-containing adenoma. gamma-Trace was also demonstrated in extracts of 1 pituitary adenoma and of 5 nontumorous adenohypophyses. The immunoreactive protein found in the extracts had a molecular weight and electrophoretic mobility characteristic of gamma-trace. Computerized amino acid sequence comparisons between the primary structure of gamma-trace and those of known hormonal peptides showed no significant similarities.
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| 8. |
- Monti, M., et al.
(author)
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Metabolic Activity of Lymphoma Cells and Clinical Course in Non‐Hodgkin Lymphoma (NHL)
- 1981
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In: Scandinavian Journal of Haematology. - : Wiley. - 1600-0609 .- 0036-553X. ; 27:5, s. 305-310
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Journal article (peer-reviewed)abstract
- By microcalorimetry the metabolic activity of malignant cells from 21 patients with non‐Hodgkin lymphoma was monitored. Heat production, a measure of the metabolic activity of cells, showed positive correlation with the clinical‐course of the disease. The heat produced by tumor cells from patients with progressive disease was 5.5 pW/cell, while that from patients responding to treatment was 3.1 pW/cell. The difference between the 2 groups is significant (P <0.05). A higher heat production was obtained in tumor cells from 7 out of 10 patients who were unresponsive to the therapy when compared with cells from 11 patients who had become asymptomatic as a result of the same therapy. Also heat production from blood lymphocytes was found to be higher (P <0.005) in the group of patients with progressive disease as compared to the group of patients who responded to therapy. The present results indicate an association between high heat production in lymphoma cells and blood lymphocytes and a poor prognosis. © Munksgaard 1981
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| 10. |
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