SwePub
Tyck till om SwePub Sök här!
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Olsson S.) srt2:(1990-1999)"

Sökning: WFRF:(Olsson S.) > (1990-1999)

  • Resultat 1-10 av 225
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  •  
2.
  •  
3.
  •  
4.
  •  
5.
  •  
6.
  •  
7.
  • Narod, S A, et al. (författare)
  • Oral contraceptives and the risk of hereditary ovarian cancer. Hereditary Ovarian Cancer Clinical Study Group
  • 1998
  • Ingår i: New England Journal of Medicine. - 0028-4793. ; 339:7, s. 8-424
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Women with mutations in either the BRCA1 or the BRCA2 gene have a high lifetime risk of ovarian cancer. Oral contraceptives protect against ovarian cancer in general, but it is not known whether they also protect against hereditary forms of ovarian cancer.METHODS: We enrolled 207 women with hereditary ovarian cancer and 161 of their sisters as controls in a case-control study. All the patients carried a pathogenic mutation in either BRCA1 (179 women) or BRCA2 (28 women). The control women were enrolled regardless of whether or not they had either mutation. Lifetime histories of oral-contraceptive use were obtained by interview or by written questionnaire and were compared between patients and control women, after adjustment for year of birth and parity.RESULTS: The adjusted odds ratio for ovarian cancer associated with any past use of oral contraceptives was 0.5 (95 percent confidence interval, 0.3 to 0.8). The risk decreased with increasing duration of use (P for trend, <0.001); use for six or more years was associated with a 60 percent reduction in risk. Oral-contraceptive use protected against ovarian cancer both for carriers of the BRCA1 mutation (odds ratio, 0.5; 95 percent confidence interval, 0.3 to 0.9) and for carriers of the BRCA2 mutation (odds ratio, 0.4; 95 percent confidence interval, 0.2 to 1.1).CONCLUSIONS: Oral-contraceptive use may reduce the risk of ovarian cancer in women with pathogenic mutations in the BRCA1 or BRCA2 gene.
  •  
8.
  •  
9.
  • Yuan, S, et al. (författare)
  • Effect of dofetilide on cardiac repolarization in patients with ventricular tachycardia. A study using simultaneous monophasic action potential recordings from two sites in the right ventricle
  • 1994
  • Ingår i: European Heart Journal. - 0195-668X. ; 15:4, s. 22-514
  • Tidskriftsartikel (refereegranskat)abstract
    • Monophasic action potentials (MAP) were simultaneously recorded from the right ventricular (RV) apex (RVA) and the outflow tract (RVOT) before and after an infusion of dofetilide in 10 patients with documented ventricular tachycardia. After the drug infusion, the MAP duration (MAPd), repolarization time, and corrected QT interval were significantly prolonged during sinus rhythm, RV pacing, and RV extra stimulation. The prolongation of MAPd at 90% repolarization during RV pacing at a cycle length of 500 ms was 31 +/- 6 ms (13%) and 26 +/- 7 ms (11%) at RVA and RVOT, respectively. The ventricular effective refractory period was significantly prolonged by 33 +/- 9 ms (13%) and 22 +/- 7 ms (9%) at driving cycle lengths 600 and 500 ms, respectively. The MAPd shortening with decreasing diastolic time intervals was significantly diminished by dofetilide in early extra beats during RV extra stimulation, suggesting a relatively more pronounced effect of this drug at the early diastolic phase. The dispersion of repolarization, defined as the difference in MAPd between RVA and RVOT, and the activation time were not significantly changed. In conclusion, acute administration of dofetilide in patients with ventricular tachycardia significantly prolonged the time intervals of ventricular repolarization and refractoriness in a parallel fashion, without affecting intraventricular conduction. The effect of dofetilide on MAPd prolongation appeared not to be reverse use-dependent in this study in humans. These results verify the selective class III antiarrhythmic property of dofetilide and warrant further studies in patients.
  •  
10.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-10 av 225
Typ av publikation
tidskriftsartikel (182)
konferensbidrag (31)
bokkapitel (6)
rapport (2)
annan publikation (2)
bok (1)
visa fler...
recension (1)
visa färre...
Typ av innehåll
refereegranskat (189)
övrigt vetenskapligt/konstnärligt (33)
populärvet., debatt m.m. (3)
Författare/redaktör
Blomgren, J (31)
Olsson, N (31)
Nilsson, L. (27)
Olsson, T (23)
Renberg, P-U (20)
Jonsson, O. (17)
visa fler...
Olsson, S (17)
Tibell, G. (17)
Conde, H (17)
Zorro, R. (14)
Olsson, Y (12)
Yuan, S (12)
Olsson, Håkan (11)
Olsson, H. (11)
Olsson, M. (11)
Elmgren, K (11)
Ringbom, A. (11)
Olsson, Bertil (10)
Olsson, P. (9)
Sharma, H S (9)
Håkansson, A. (8)
Carlsson, J (8)
Dangtip, S (8)
Olsson, R (7)
Holm, M. (7)
Pehrson, S. (7)
Brandenburg, S (7)
Nilsson, J. (6)
Odlind, V (6)
Nilsson, S. (6)
Olsson, L E (6)
Mattsson, S. (6)
Prytz, H. (6)
Blomström-Lundqvist, ... (6)
Sjöberg, S (6)
Rahm, J (6)
Österlund, M. (6)
Chmielewska, D (6)
van der Woude, A (6)
Olsson, S B (6)
Johansson, Rolf (5)
Olsson, Jörgen (5)
Landin-Olsson, M (5)
Loof, L (5)
van Hage-Hamsten, M (5)
Stalberg, E (5)
Fransson, A. (5)
Tydén, Tanja, 1949- (5)
Hultqvist, S (5)
Blomström, P (5)
visa färre...
Lärosäte
Uppsala universitet (98)
Karolinska Institutet (64)
Lunds universitet (50)
Linköpings universitet (7)
Umeå universitet (5)
Kungliga Tekniska Högskolan (5)
visa fler...
Luleå tekniska universitet (4)
Göteborgs universitet (2)
Linnéuniversitetet (2)
Högskolan i Halmstad (1)
Jönköping University (1)
Mittuniversitetet (1)
Södertörns högskola (1)
visa färre...
Språk
Engelska (218)
Svenska (6)
Kinesiska (1)
Forskningsämne (UKÄ/SCB)
Medicin och hälsovetenskap (48)
Naturvetenskap (9)
Teknik (9)
Samhällsvetenskap (3)

År

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy