Sökning: WFRF:(Oreland Lars)
> Norska >
Transcription Facto...
Transcription Factor Activating Protein-2β (TFAP-2β) genotype and symptoms of attention deficit hyperactivity disorder in relation to symptoms of depression in two independent samples
-
- Nilsson, Kent W. (författare)
- Uppsala universitet,Centrum för klinisk forskning, Västerås,Uppsala Univ, Vastmanland Cty Hosp, Clin Res Ctr, S-72189 Vasteras, Sweden.,Centre for Clinical Research, Västmanland County Hospital, Uppsala University, 721 89, Västerås, Sweden
-
- Sonnby, Karin (författare)
- Uppsala universitet,Centrum för klinisk forskning, Västerås,Uppsala Univ, Vastmanland Cty Hosp, Clin Res Ctr, S-72189 Vasteras, Sweden.,Centre for Clinical Research, Västmanland County Hospital, Uppsala University, 721 89, Västerås, Sweden
-
- Nordquist, Niklas (författare)
- Uppsala universitet,Institutionen för neurovetenskap,Uppsala Univ, Dept Neurosci, S-75124 Uppsala, Sweden.,Department of Neuroscience, Uppsala University, POB 593, 751 24, Uppsala, Sweden
-
visa fler...
-
- Comasco, Erica (författare)
- Uppsala universitet,Neuropsykofarmakologi,Uppsala Univ, Dept Neurosci, S-75124 Uppsala, Sweden.,Department of Neuroscience, Uppsala University, POB 593, 751 24, Uppsala, Sweden
-
- Leppert, Jerzy (författare)
- Uppsala universitet,Centrum för klinisk forskning, Västerås,Uppsala Univ, Vastmanland Cty Hosp, Clin Res Ctr, S-72189 Vasteras, Sweden.,Centre for Clinical Research, Västmanland County Hospital, Uppsala University, 721 89, Västerås, Sweden
-
- Oreland, Lars (författare)
- Uppsala universitet,Neuropsykofarmakologi,Uppsala Univ, Dept Neurosci, S-75124 Uppsala, Sweden.,Department of Neuroscience, Uppsala University, POB 593, 751 24, Uppsala, Sweden
-
- Sjöberg, Rickard L. (författare)
- Umeå universitet,Klinisk neurovetenskap
-
visa färre...
-
(creator_code:org_t)
- 2013-07-04
- 2014
- Norska.
-
Ingår i: European Child and Adolescent Psychiatry. - Berlin Heidelberg : Springer Science and Business Media LLC. - 1018-8827 .- 1435-165X. ; 23:4, s. 207-217
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
https://urn.kb.se/re...
-
visa färre...
Abstract
Ämnesord
Stäng
- The Transcription Factor Activating Protein-2β (TFAP-2β) gene has been shown to influence monoaminergic neurotransmission, and several genes important for monoaminergic function have binding sites for TFAP-2β. Familial studies of attention deficit hyperactivity disorder (ADHD) suggest a hereditary-determined subtype of ADHD with comorbid depression. We examined a functional variation of the TFAP-2β gene in the context of co-occurring symptoms of ADHD and depression in two independent population-based samples of adolescents (Group A, n = 175 and Group B, n = 1,506) from Sweden. Results indicated 6.1 to 7.8 % of adolescents screened positively for ADHD and depression symptoms. Symptoms of depression were more common among girls who screened positively for ADHD and did not carry the nine-repeat allele of the TFAP-2β intron 1 Variable Number Tandem Repeat (VNTR) polymorphism. The presence of the nine-repeat variant of the TFAP-2β intron 1 VNTR appears to protect girls with ADHD symptoms from the co-expression of symptoms of depression.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Nyckelord
- attention deficit hyperactivity disorder
- depression
- adolescents
- comorbitidy
- transcription factor AP-2β
-
- Child and Youth Psychiatry
- Barn- och ungdomspsykiatri
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas