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Sökning: WFRF:(Patel Vyoma K.) > (2023) > Tackling the cytoki...

Tackling the cytokine storm using advanced drug delivery in allergic airway disease

Patel, Vyoma K. (författare)
Univ Technol Sydney, Grad Sch Hlth, Discipline Pharm, POB 123 Broadway, Ultimo, NSW 2007, Australia.;Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia.;Univ New South Wales, Fac Med & Hlth, Sch Clin Med, Sydney, NSW 2052, Australia.
Vishwas, Sukriti (författare)
Lovely Profess Univ, Sch Pharmaceut Sci, Phagwara, Punjab, India.
Kumar, Rajan (författare)
Lovely Profess Univ, Sch Pharmaceut Sci, Phagwara, Punjab, India.
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De Rubis, Gabriele (författare)
Univ Technol Sydney, Grad Sch Hlth, Discipline Pharm, POB 123 Broadway, Ultimo, NSW 2007, Australia.;Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia.
Shukla, Shakti D. (författare)
Univ Technol Sydney, Grad Sch Hlth, Discipline Pharm, POB 123 Broadway, Ultimo, NSW 2007, Australia.;Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia.
Paudel, Keshav Raj (författare)
Centenary Inst, Ctr Inflammat, Sydney, NSW 2007, Australia.;Univ Technol Sydney, Fac Sci, Sch Life Sci, Sydney, NSW 2007, Australia.
Manandhar, Bikash (författare)
Univ Technol Sydney, Grad Sch Hlth, Discipline Pharm, POB 123 Broadway, Ultimo, NSW 2007, Australia.;Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia.
Singh, Thakur Gurjeet (författare)
Chitkara Univ, Chitkara Coll Pharm, Rajpura 140401, Punjab, India.
Chellappan, Dinesh Kumar (författare)
Int Med Univ, Sch Pharm, Dept Life Sci, Kuala Lumpur 57000, Malaysia.
Gulati, Monica (författare)
Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia.;Lovely Profess Univ, Sch Pharmaceut Sci, Phagwara, Punjab, India.
Kaur, Indu Pal (författare)
Panjab Univ, Univ Inst Pharmaceut Sci, Chandigarh 160014, India.
Allam, Venkata Sita Rama Raju (författare)
Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
Hansbro, Philip M. (författare)
Centenary Inst, Ctr Inflammat, Sydney, NSW 2007, Australia.;Univ Technol Sydney, Fac Sci, Sch Life Sci, Sydney, NSW 2007, Australia.
Oliver, Brian G. (författare)
Univ Technol Sydney, Fac Sci, Sch Life Sci, Ultimo, NSW, Australia.;Univ Sydney, Woolcock Inst Med Res, Sydney, NSW, Australia.
MacLoughlin, Ronan (författare)
Aerogen Ltd, IDA Business Pk, Galway H91 HE94, Ireland.;Royal Coll Surgeons Ireland, Sch Pharm & Biomol Sci, Dublin D02 YN77, Ireland.;Trinity Coll Dublin, Sch Pharm & Pharmaceut Sci, Dublin D02 PN40, Ireland.
Singh, Sachin Kumar (författare)
Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia.;Lovely Profess Univ, Sch Pharmaceut Sci, Phagwara, Punjab, India.
Dua, Kamal (författare)
Univ Technol Sydney, Grad Sch Hlth, Discipline Pharm, POB 123 Broadway, Ultimo, NSW 2007, Australia.;Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia.;Uttaranchal Univ, Uttaranchal Inst Pharmaceut Sci, Dehra Dun 248007, Uttarakhand, India.
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Univ Technol Sydney, Grad Sch Hlth, Discipline Pharm, POB 123 Broadway, Ultimo, NSW 2007, Australia;Univ Technol Sydney, Fac Hlth, Australian Res Ctr Complementary & Integrat Med, Ultimo, NSW 2007, Australia.;Univ New South Wales, Fac Med & Hlth, Sch Clin Med, Sydney, NSW 2052, Australia. Lovely Profess Univ, Sch Pharmaceut Sci, Phagwara, Punjab, India. (creator_code:org_t)
Elsevier, 2023
2023
Engelska.
Ingår i: Journal of Drug Delivery Science and Technology. - : Elsevier. - 1773-2247. ; 82
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.1...
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  • Forskningsöversikt (refereegranskat)
Abstract Ämnesord
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  • Asthma is one of the leading causes of mortality worldwide presenting a huge socio-economic burden with rising morbidity and mortality rates. It is a chronic inflammatory airway disease that is eminent with multiple epidemiological and pathophysiological features such as over production of pro-inflammatory cytokines that triggers an uncontrolled aberrant inflammatory response known as 'cytokine storm'. This phenomenon interferes with the signalling and production of cytokines over time leading to the progression of disease and the development of complications that lead to fatal consequences in many individuals. Targeting this overproduction and signalling of cytokines may prove a promising approach to develop novel cytokine specific therapies in the treatment of asthma. This review discusses on the various pharmacological strategies, recent advancements in drug delivery systems and significant findings from clinical trials that may have a potential to outweigh the limitations of the current therapies in the treatment of asthma.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)

Nyckelord

Asthma
Cytokines
Drug delivery systems
Clinical trials

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