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- Neumann, A, et al.
(författare)
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A genome-wide association study of total child psychiatric problems scores
- 2022
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Ingår i: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 17:8, s. e0273116-
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Tidskriftsartikel (refereegranskat)abstract
- Substantial genetic correlations have been reported across psychiatric disorders and numerous cross-disorder genetic variants have been detected. To identify the genetic variants underlying general psychopathology in childhood, we performed a genome-wide association study using a total psychiatric problem score. We analyzed 6,844,199 common SNPs in 38,418 school-aged children from 20 population-based cohorts participating in the EAGLE consortium. The SNP heritability of total psychiatric problems was 5.4% (SE = 0.01) and two loci reached genome-wide significance: rs10767094 and rs202005905. We also observed an association of SBF2, a gene associated with neuroticism in previous GWAS, with total psychiatric problems. The genetic effects underlying the total score were shared with common psychiatric disorders only (attention-deficit/hyperactivity disorder, anxiety, depression, insomnia) (rG > 0.49), but not with autism or the less common adult disorders (schizophrenia, bipolar disorder, or eating disorders) (rG < 0.01). Importantly, the total psychiatric problem score also showed at least a moderate genetic correlation with intelligence, educational attainment, wellbeing, smoking, and body fat (rG > 0.29). The results suggest that many common genetic variants are associated with childhood psychiatric symptoms and related phenotypes in general instead of with specific symptoms. Further research is needed to establish causality and pleiotropic mechanisms between related traits.
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- Alves, Dimas I, et al.
(författare)
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A Statistical Analysis for Wavelength-Resolution SAR Image Stacks
- 2020
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Ingår i: IEEE Geoscience and Remote Sensing Letters. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 1545-598X .- 1558-0571. ; 17:2, s. 227-231
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Tidskriftsartikel (refereegranskat)abstract
- This letter presents a clutter statistical analysis for stacks of wavelength-resolution synthetic aperture radar (SAR) images. Each image stack consists of SAR images generated by the same sensor, using the same flight track illuminating the same scene but with a time separation between the illuminations. We test three candidate statistical distributions for time changes in the stack, namely, Rician, Rayleigh, and log-normal. The tests results reveal that the Rician distribution is a very good candidate for modeling stack of wavelength-resolution SAR images, where 98.59 & x0025; of the tested samples passed the Anderson-Darling (AD) goodness-of-fit test. Also, it is observed that the presence of changes in the ground scene is related to the tested samples that have failed in the AD test for the Rician distribution hypothesis.
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- Alves, Dimas, I, et al.
(författare)
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Incoherent Change Detection Methods for Wavelength-Resolution SAR Image Stacks Based on Masking Techniques
- 2020
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Ingår i: 2020 IEEE National Radar Conference - Proceedings. - : IEEE. - 9781728189420
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Konferensbidrag (refereegranskat)abstract
- This paper presents two incoherent change detection methods for wavelength-resolution synthetic aperture radars (SAR) image stacks based on masking techniques. The first technique proposed is the Simple Masking Detection (SMD). This method uses the statistical behavior of pixels-sets in the image stack to create a binary mask, which is used to remove pixels that are not related to changes in a surveillance image from the same interest region. The second technique is the Multiple Concatenated Masking Detection (MCMD), which produces a more selective mask than the SMD by concatenating multiple masks from different image stacks. The MCMD can be used in specific applications where multiple stacks share common patterns of target deployments. Both proposed techniques were evaluated using 24 incoherent SAR images obtained by the CARABAS II system. The experimental results revealed that the proposed detection methods have better performance in terms of probability of detection and false alarm rate when compared with other change detection techniques, especially for high detection probabilities scenarios.
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- Alves, Dimas I., et al.
(författare)
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Neyman-Pearson Criterion-Based Change Detection Methods for Wavelength-Resolution SAR Image Stacks
- 2022
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Ingår i: IEEE Geoscience and Remote Sensing Letters. - : Institute of Electrical and Electronics Engineers Inc.. - 1545-598X .- 1558-0571. ; 19
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Tidskriftsartikel (refereegranskat)abstract
- This letter presents two new change detection (CD) methods for synthetic aperture radar (SAR) image stacks based on the Neyman-Pearson criterion. The first proposed method uses the data from wavelength-resolution images stack to obtain background statistics, which are used in a hypothesis test to detect changes in a surveillance image. The second method considers a priori information about the targets to obtain the target statistics, which are used together with the previously obtained background statistics, to perform a hypothesis test to detect changes in a surveillance image. A straightforward processing scheme is presented to test the proposed CD methods. To assess the performance of both proposed methods, we considered the coherent all radio band sensing (CARABAS)-II SAR images. In particular, to obtain the temporal background statistics required by the derived methods, we used stacks with six images. The experimental results show that the proposed techniques provide a competitive performance in terms of probability of detection and false alarm rate compared with other CD methods. CCBY
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- Alves, Dimas I, et al.
(författare)
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Statistical Analysis for Wavelength-Resolution SARImage Stacks : New Case Studies
- 2020
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Ingår i: XXXVIII SIMPÓSIO BRASILEIRO DE TELECOMUNICAÇÕES E PROCESSAMENTO DE SINAIS.
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Konferensbidrag (refereegranskat)abstract
- This paper presents new case studies for thestatistical analysis for wavelength resolution SAR image stacks.The statistical analysis considers the Anderson-Darling goodnessof-fit test in a set of pixel samples from the same position obtainedfrom a SAR image stack. The test is applied in wavelengthresolution SAR image stacks. The present work consists of twocase studies based on the use of multiple-pass stacks and TypeI error using the False Discovery Rate controlling procedures.In addition, an application scenario is presented for the studiedscenarios.
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- Bagni, Tommaso, et al.
(författare)
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Modeling Results of the Quench Behavior of a Nb-Ti Canted-Cosine-Theta Corrector Magnet for LHC
- 2024
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Ingår i: IEEE transactions on applied superconductivity (Print). - : Institute of Electrical and Electronics Engineers (IEEE). - 1051-8223 .- 1558-2515. ; 34:5, s. 1-5
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Tidskriftsartikel (refereegranskat)abstract
- A newly designed superconducting magnet of the Canted-Cosine-Theta (CCT) type was developed as a result of a collaboration between Swedish universities (Uppsala and Linneaus) and Swedish industries. This magnet was designed to function as a replacement of the present LHC orbit corrector magnets, which are approaching their end of life due to the radiation load. As a result, the new CCT magnet was developed to be more radiation tolerant and to constitute a one-to-one replacement to the currently installed version, which is a 1 m long 70 mm double aperture dipole magnet. The final magnet, which is currently under construction, will be tested at FREIA laboratory at Uppsala University and generate a magnetic field of 3.3 T and an integrated field of 2.8 Tm at about 85 A. To examine the magnet quench behavior and to identify a suitable quench protection system, the 3D electro-magnetic and thermal behavior of the coil was modeled using the RAT-Raccoon software. Based on the simulation results, a Metrosil varistor was selected to protect the magnet during the test. In this article, we report the results of the numerical analysis. The magnet model is equipped with a spot heater to initialize the quench and the temperature and voltages are monitored during the avalanche effect. The simulated current decay and the hot-spot temperature are analyzed with a focus on the impact of quench-back on the magnet protection.
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